Vaccination against Oncoproteins of HPV16 for Noninvasive Vulvar/Vaginal Lesions: Lesion Clearance Is Related to the Strength of the T-Cell Response.

Autor: van Poelgeest MI; Department of Gynaecology, Leiden University Medical Centre, Leiden, the Netherlands., Welters MJ; Department of Clinical Oncology, Leiden University Medical Centre, Leiden, the Netherlands., Vermeij R; Department of Gynaecology, University Medical Centre Groningen, Groningen, the Netherlands., Stynenbosch LF; Department of Clinical Oncology, Leiden University Medical Centre, Leiden, the Netherlands., Loof NM; Department of Clinical Oncology, Leiden University Medical Centre, Leiden, the Netherlands., Berends-van der Meer DM; Department of Gynaecology, Leiden University Medical Centre, Leiden, the Netherlands., Löwik MJ; Department of Gynaecology, Leiden University Medical Centre, Leiden, the Netherlands., Hamming IL; Department of Gynaecology, University Medical Centre Groningen, Groningen, the Netherlands., van Esch EM; Department of Gynaecology, Leiden University Medical Centre, Leiden, the Netherlands., Hellebrekers BW; Department of Obstetrics and Gynaecology, Haga Teaching Hospital, the Hague, the Netherlands., van Beurden M; Netherlands Cancer Institute, Amsterdam, the Netherlands., Schreuder HW; Department of Obstetrics and Gynaecology, University Medical Centre Utrecht, Utrecht, the Netherlands., Kagie MJ; Department of Obstetrics and Gynaecology, Medical Centre Haaglanden, the Hague, the Netherlands., Trimbos JB; Department of Gynaecology, Leiden University Medical Centre, Leiden, the Netherlands., Fathers LM; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Centre, Leiden, the Netherlands., Daemen T; Department of Medical Microbiology, University Medical Centre Groningen, Groningen, the Netherlands., Hollema H; Department of Pathology and Medical Biology, University Medical Centre Groningen, Groningen, the Netherlands., Valentijn AR; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Centre, Leiden, the Netherlands., Oostendorp J; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Centre, Leiden, the Netherlands., Oude Elberink JH; Department of Allergy, Internal Medicine, Groningen Research Institute for Asthma and COPD, University Medical Centre Groningen, Groningen, the Netherlands., Fleuren GJ; Department of Pathology, Leiden University Medical Centre, Leiden, the Netherlands., Bosse T; Department of Pathology, Leiden University Medical Centre, Leiden, the Netherlands., Kenter GG; Department of Gynaecology, Academic Medical Centre, Amsterdam, the Netherlands., Stijnen T; Department of Medical Statistics and Bioinformatics, Leiden University Medical Centre, Leiden, the Netherlands., Nijman HW; Department of Gynaecology, University Medical Centre Groningen, Groningen, the Netherlands., Melief CJ; ISA Pharmaceuticals, Leiden, the Netherlands. Immunohematology and Blood Transfusion, Leiden University Medical Centre, Leiden, the Netherlands., van der Burg SH; Department of Clinical Oncology, Leiden University Medical Centre, Leiden, the Netherlands. shvdburg@lumc.nl.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2016 May 15; Vol. 22 (10), pp. 2342-50. Date of Electronic Publication: 2016 Jan 26.