Demyelinating polyneuropathy in goats lacking prion protein.

Autor: Skedsmo FS; Department of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Oslo, Norway., Malachin G; Department of Basic Sciences and Aquatic Medicine, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Oslo, Norway., Våge DI; Centre for Integrative Genetics (CIGENE), Department of Animal and Aquacultural Sciences, Faculty of Biosciences, Norwegian University of Life Sciences, Ås, Norway., Hammervold MM; Centre for Integrative Genetics (CIGENE), Department of Animal and Aquacultural Sciences, Faculty of Biosciences, Norwegian University of Life Sciences, Ås, Norway., Salvesen Ø; Department of Production Animal Clinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Oslo, Norway., Ersdal C; Department of Production Animal Clinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Oslo, Norway., Ranheim B; Department of Production Animal Clinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Oslo, Norway., Stafsnes MH; Department of Biotechnology and Food Science, Faculty of Natural Sciences, Norwegian University of Science and Technology, Trondheim, Norway., Bartosova Z; Department of Biotechnology and Food Science, Faculty of Natural Sciences, Norwegian University of Science and Technology, Trondheim, Norway., Bruheim P; Department of Biotechnology and Food Science, Faculty of Natural Sciences, Norwegian University of Science and Technology, Trondheim, Norway., Jäderlund KH; Department of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Oslo, Norway., Matiasek K; Section of Clinical & Comparative Neuropathology, Centre for Clinical Veterinary Medicine, Ludwig-Maximilians-Universität, Munich, Germany., Espenes A; Department of Basic Sciences and Aquatic Medicine, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Oslo, Norway., Tranulis MA; Department of Basic Sciences and Aquatic Medicine, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Oslo, Norway.

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2020 Feb; Vol. 34 (2), pp. 2359-2375. Date of Electronic Publication: 2019 Dec 13.

Investigating CRISPR/Cas9 gene drive for production of disease-preventing prion gene alleles.

Autor: Castle, Andrew R.^1,2 (AUTHOR), Wohlgemuth, Serene^1,2 (AUTHOR), Arce, Luis^1,3 (AUTHOR), Westaway, David^1,2,3 (AUTHOR) david.westaway@ualberta.ca

Publikováno v: PLoS ONE. 6/7/2022, Vol. 17 Issue 6, p1-21. 21p.

Soluble dimeric prion protein ligand activates Adgrg6 receptor but does not rescue early signs of demyelination in PrP-deficient mice.

Autor: Henzi, Anna¹ (AUTHOR), Senatore, Assunta¹ (AUTHOR), Lakkaraju, Asvin K. K.¹ (AUTHOR), Scheckel, Claudia¹ (AUTHOR), Mühle, Jonas² (AUTHOR), Reimann, Regina¹ (AUTHOR), Sorce, Silvia¹ (AUTHOR), Schertler, Gebhard² (AUTHOR), Toyka, Klaus V.³ (AUTHOR), Aguzzi, Adriano¹ (AUTHOR) adriano.aguzzi@usz.ch

Publikováno v: PLoS ONE. 11/12/2020, Vol. 15 Issue 11, p1-22. 22p.