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pro vyhledávání: '"Hammer Robert Paul"'
Autor:
Douglas A. Treco, Dhamnaskar Ketki Ashok, Kathleen Seyb, Demarco Steven James, Vaishnavi Rajagopal, Michelle Denise Arata, Masha Fridkis-Hareli, Guo-Qing Tang, Hammer Robert Paul, Alonso Ricardo, Sylvia Tobe
Publikováno v:
Blood. 126:939-939
Regulation of the terminal phase of the complement component pathway is a clinically validated approach for the therapeutic treatment of complement disorders. Inhibition of complement activation at the C5 level with the monoclonal antibody eculizumab
Autor:
Dhamnaskar Ketki Ashok, Hammer Robert Paul, Hong Zheng, Zhaolin Wang, Sylvia Tobe, Kristopher Josephson, Douglas A. Treco, Michelle Denise Arata, Alonso Ricardo, Demarco Steven James, Kathleen Seyb
Publikováno v:
Blood. 124:2936-2936
The involvement of complement in the pathogenesis of serious, life-threatening diseases underscores the importance in developing therapeutics to intervene in this cascade. Specifically, dysregulation of the complement system is central in multiple he