Potential Involvement of Peroxisome in Multiple Sclerosis and Alzheimer's Disease : Peroxisome and Neurodegeneration

Autor: Amira, Zarrouk, Thomas, Nury, Hammam I, El Hajj, Catherine, Gondcaille, Pierre, Andreoletti, Thibault, Moreau, Mustapha, Cherkaoui-Malki, Johannes, Berger, Mohamed, Hammami, Gérard, Lizard, Anne, Vejux

Publikováno v: Advances in experimental medicine and biology. 1299

Peroxisomopathies are rare diseases due to dysfunctions of the peroxisome in which this organelle is either absent or with impaired activities. These diseases, at the exception of type I hyperoxaluria and acatalasaemia, affect the central and periphe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::07077f46129cc615e7c16222a6e40aff
https://pubmed.ncbi.nlm.nih.gov/33417210

Modulation of peroxisomes abundance by argan oil and lipopolysaccharides in acyl-CoA oxidase 1-deficient fibroblasts

Autor: Gérard Lizard, Pierre Andreoletti, Joseph Vamecq, Soufiane El Kamouni, Riad El Kebbaj, Joseph Gresti, Hammam I. El Hajj, Norbert Latruffe, Boubker Nasser, M'Hammed Saïd El Kebbaj, Mustapha Cherkaoui-Malki

Publikováno v: Health. :62-69

Pseudo-neonatal adrenoleukodystrophy (P-NALD) is a neurodegenerative disorder caused by acyl-CoA oxidase 1 (ACOX1) deficiency with subsequent impairment of peroxisomal fatty acid β-oxidation, accumulation of very long chain fatty acids (VLCFAs) and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c9d2a0d10b4a3822abb36080ea2fd05e
https://doi.org/10.4236/health.2013.51009

Argan oil prevents down-regulation induced by endotoxin on liver fatty acid oxidation and gluconeogenesis and on peroxisome proliferator-activated receptor gamma coactivator-1 alpha, (PGC-1alpha), peroxisome proliferator-activated receptor gamma (PPARgamma) and estrogen related receptor alpha (ERRalpha)

Autor: Gérard Lizard, Hammam I. El Hajj, Norbert Latruffe, Pierre Andreoletti, Mustapha Cherkaoui-Malki, Fatima-Ezzahra Saih, Joseph Vamecq, Riad El Kebbaj, Boubker Nasser, Youssef El Kharrassi, M'Hammed Saïd El Kebbaj, Stéphane Mandard

Publikováno v: Biochimie Open
Biochimie Open, Elsevier, 2015, 1, pp.51-59. ⟨10.1016/j.biopen.2015.10.002⟩
Biochimie Open, 2015, 1, pp.51-59. ⟨10.1016/j.biopen.2015.10.002⟩
Biochimie Open, Vol 1, Iss C, Pp 51-59 (2015)
Biochimie Open, [Amsterdam] : Published by Elsevier B.V. on behalf of Société Française de Biochimie et Biologie Moléculaire (SFBBM), [2015]-, 2015, 1, pp.51-59. 〈10.1016/j.biopen.2015.10.002〉

In patients with sepsis, liver metabolism and its capacity to provide other organs with energetic substrates are impaired. This and many other pathophysiological changes seen in human patients are reproduced in mice injected with purified endotoxin (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df3b3dce7a010d7619ed5b7b1e2f9f7e
https://www.hal.inserm.fr/inserm-01534672/file/BiochimieOpen2015ElKebbaj.pdf

Hepatic steatosis and peroxisomal fatty acid beta-oxidation

Autor: Sailesh Surapureddi, Mustapha Cherkaoui-Malki, Joseph Vamecq, Hammam I El-Hajj, Pierre Andreoletti

Publikováno v: Current drug metabolism. 13(10)

Three subhepatocellular compartments concur for fatty acids degradation including ω-oxidation in endoplasmic reticulum and β-oxidation in both mitochondria and peroxisomes. Deficits affecting the peroxisomal physiology may be associated with multip

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a0775591257b4686c6ba24869cfb4a
https://pubmed.ncbi.nlm.nih.gov/22978396