Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Hamish B Pegg"'
Autor:
Matthew E Cockman, Kerstin Lippl, Ya-Min Tian, Hamish B Pegg, William D Figg Jnr, Martine I Abboud, Raphael Heilig, Roman Fischer, Johanna Myllyharju, Christopher J Schofield, Peter J Ratcliffe
Publikováno v:
eLife, Vol 8 (2019)
Human and other animal cells deploy three closely related dioxygenases (PHD 1, 2 and 3) to signal oxygen levels by catalysing oxygen regulated prolyl hydroxylation of the transcription factor HIF. The discovery of the HIF prolyl-hydroxylase (PHD) enz
Externí odkaz:
https://doaj.org/article/70d88ea4f82c4443ab41453328102032
Autor:
Matthew E. Cockman, Yoichiro Sugimoto, Hamish B. Pegg, Norma Masson, Eidarus Salah, Anthony Tumber, Helen R. Flynn, Joanna M. Kirkpatrick, Christopher J. Schofield, Peter J. Ratcliffe
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(32)
The Jumonji domain–containing protein JMJD6 is a 2-oxoglutarate–dependent dioxygenase associated with a broad range of biological functions. Cellular studies have implicated the enzyme in chromatin biology, transcription, DNA repair, mRNA splicin
Autor:
Michael J. Thomas, Wes Pawloski, George H. Lorimer, David Fushman, Victoria L. Linthwaite, Adrian P. Brown, Victor K. H. So, Martin J. Cann, Hamish B. Pegg, David R. W. Hodgson, Philip D. Townsend
Publikováno v:
Science Advances
Science advances, 2021, Vol.7(39), pp.eabi5507 [Peer Reviewed Journal]
Science advances, 2021, Vol.7(39), pp.eabi5507 [Peer Reviewed Journal]
Description
Altered ubiquitin conjugation is a mechanism by which mammalian cells can respond to fluctuating pCO2.
The identification of CO2-binding proteins is crucial to understanding CO2-regulated molecular processes. CO2 can form a reve
Altered ubiquitin conjugation is a mechanism by which mammalian cells can respond to fluctuating pCO2.
The identification of CO2-binding proteins is crucial to understanding CO2-regulated molecular processes. CO2 can form a reve
Autor:
Johanna Myllyharju, Roman Fischer, William D Figg Jnr, Kerstin Lippl, Raphael Heilig, Christopher J. Schofield, Matthew E. Cockman, Ya-Min Tian, Martine I. Abboud, Hamish B Pegg, Peter J. Ratcliffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ed9be5c54cd1c00ac767438b749412d
https://doi.org/10.7554/elife.46490.072
https://doi.org/10.7554/elife.46490.072