Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hamida Saba"'
Publikováno v:
Free Radical Biology and Medicine. 56:54-63
Mitochondria are at the heart of all cellular processes as they provide the majority of the energy needed for various metabolic processes. Nitric oxide has been shown to have numerous roles in the regulation of mitochondrial function. Mitochondria ha
Autor:
Takuji Shirasawa, Takahiko Shimizu, Tanecia Mitchell, Akira Marine, Hamida Saba, Lee Ann MacMillan-Crow, Sloane Simmons, Nirmala Parajuli
Publikováno v:
Free Radical Biology and Medicine. 51:406-416
Inactivation of manganese superoxide dismutase (MnSOD), a mitochondrial antioxidant, has been associated with renal disorders and often results in detrimental downstream events that are mechanistically not clear. Development of an animal model that e
Autor:
Michael P. Murphy, Robin A.J. Smith, Dumitru Rotaru, Tanecia Mitchell, Lee Ann MacMillan-Crow, Hamida Saba
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 336:682-692
The majority of kidneys used for transplantation are obtained from deceased donors. These kidneys must undergo cold preservation/storage before transplantation to preserve tissue quality and allow time for recipient selection and transport. However,
Autor:
Shankar Munusamy, Hamida Saba, Lee Ann MacMillan-Crow, Ines Batinic-Haberle, Judit Megyesi, Cheryl F. Lichti, Tanecia Mitchell
Publikováno v:
Free Radical Biology and Medicine. 42:1571-1578
Renal ischemia/reperfusion (I/R) injury often occurs as a result of vascular surgery, organ procurement, or transplantation. We previously showed that renal I/R results in ATP depletion, oxidant production, and manganese superoxide dismutase (MnSOD)
Publikováno v:
The Journal of the Arkansas Medical Society. 111(6)
Tuberculosis (TB) is one of the leading causes of morbidity and mortality in the world. Its classic forms include cavitary and miliary TB. The non-specific clinical presentation of TB and similarity of its signs and symptoms with other pulmonary dise
Publikováno v:
Archives of Biochemistry and Biophysics. 437:96-105
We have previously shown that in vivo renal ischemia/reperfusion results in ATP depletion, oxidant production, and manganese superoxide dismutase (MnSOD) inactivation. Current studies were designed to compare the effect of ATP depletion (Antimycin A
Publikováno v:
Australasian Medical Journal. 7
Mycobacterium tuberculosis remains one of the most significant causes of death from an infectious agent. Rapid and accurate diagnosis of pulmonary and extra-pulmonary tuberculosis (TB) is still a great challenge. The GeneXpert MTB/RIF assay is a nove
Autor:
Laura P. James, Tonya M. Rafferty, E. Kim Fifer, Jack A. Hinson, Lee Ann MacMillan-Crow, Rakhee Agarwal, Hamida Saba, Dean W. Roberts
In overdose the analgesic/antipyretic acetaminophen (APAP) is hepatotoxic. Toxicity is mediated by initial hepatic metabolism to N-acetyl-p-benzoquinone imine (NAPQI). After low doses NAPQI is efficiently detoxified by GSH. However, in overdose GSH i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c836ea9e2f7bb3526fa2e49ea1f6915
https://europepmc.org/articles/PMC3063736/
https://europepmc.org/articles/PMC3063736/
Publikováno v:
Free radical biologymedicine. 49(8)
Cold storage (CS) is regarded as a necessary procedure during donation of a deceased donor kidney that helps to optimize organ viability. Increased oxidant generation during both CS as well as during the reperfusion (or rewarming/CS.RW) phase have be
Publikováno v:
The FASEB Journal. 24