Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Hamid R. Nasiri"'
Autor:
Jan Kägi, Willough Sloan, Johannes Schimpf, Hamid R. Nasiri, Dana Lashley, Thorsten Friedrich
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Bacterial energy metabolism has become a promising target for next-generation tuberculosis chemotherapy. One strategy to hamper ATP production is to inhibit the respiratory oxidases. The respiratory chain of Mycobacterium tuberculosis compri
Externí odkaz:
https://doaj.org/article/0872ca2c0d1947a59e82b4616c2abb39
Autor:
Iryna Makarchuk, Anton Nikolaev, Alexander Thesseling, Lisa Dejon, Daniel Lamberty, Laura Stief, Thorsten Friedrich, Petra Hellwig, Hamid R. Nasiri, Frederic Melin
Publikováno v:
The 1st International Electronic Conference on Chemical Sensors and Analytical Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db6ddbc40e91f8e078ba5166c421af80
https://doi.org/10.3390/csac2021-10555
https://doi.org/10.3390/csac2021-10555
Autor:
Hamid R. Nasiri, Harald Schwalbe, Hubert Serve, Santosh Lakshmi Gande, Julia Wirmer-Bartoschek, Islam Alshamleh, Marcel Seibert, Frank Schnütgen, Vijaykumar D. Nimbarte
Publikováno v:
Chemmedchem
Lead‐optimization strategies for compounds targeting c‐Myc G‐quadruplex (G4) DNA are being pursued to develop anticancer drugs. Here, we investigate the structure‐activity‐ relationship (SAR) of a newly synthesized series of molecules based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28122d085106508df0093ecc5de17fd2
https://pubmed.ncbi.nlm.nih.gov/33508167
https://pubmed.ncbi.nlm.nih.gov/33508167
Autor:
Zahra Hassanpour, Sofie Schaerlaekens, Hamid R. Nasiri, Samad Nejad-Ebrahimi, María A. Oliva, Morteza Bararjanian, Faezeh Nemati, Maryam Mohebbi, Yvonne Jung, Robert Fürst, Daniel Lucena-Agell, Nasim Hadian, Peyman Salehi, Iris Bischoff-Kont
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
53 p.-7 fig.-1 tab.-1 schem.-1 graph. abst.
Noscapine is a natural product first isolated from the opium poppy (Papaver somniferum L.) with anticancer properties. In this work, we report the synthesis and cellular screening of a noscapine-based
Noscapine is a natural product first isolated from the opium poppy (Papaver somniferum L.) with anticancer properties. In this work, we report the synthesis and cellular screening of a noscapine-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce2919b609c0a0107af13e3ddcc88eca
http://hdl.handle.net/10261/249104
http://hdl.handle.net/10261/249104
Autor:
Hamid R. Nasiri, Karina Tuz, Iris Bischoff, Robert Fürst, Zhenyu Han, Oscar Juárez, Yihan Qin, Günter Fritz, Heike Angerer, Dana Lashley, Dennis P. Stegmann
Publikováno v:
ChemMedChem. 15(24)
A short, efficient one-step synthesis of 2-methyl-5-(3-methyl-2-butenyl)-1,4-benzoquinone, a natural product from Pyrola media is described. The synthesis is based on a direct late C-H functionalization of the quinone scaffold. The formation of the n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::287bdf60b53137fe8c39b5f371632347
https://pubmed.ncbi.nlm.nih.gov/32730688
https://pubmed.ncbi.nlm.nih.gov/32730688
Autor:
Michael Bolte, Vijaykumar D. Nimbarte, Melanie Radloff, Hartmut Michel, Hamid R. Nasiri, Harald Schwalbe, Katharina F. Hohmann, Isam Elamri, Schara Safarian
Publikováno v:
Chemmedchem
The respiratory chain of Escherichia coli contains two different types of terminal oxidase that are differentially regulated as a response to changing environmental conditions. These oxidoreductases catalyze the reduction of molecular oxygen to water
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93889b8d23f17437774112f862e30f8f
http://publikationen.ub.uni-frankfurt.de/files/56501/container.zip
http://publikationen.ub.uni-frankfurt.de/files/56501/container.zip
Publikováno v:
Analytical Biochemistry. 537:56-59
We demonstrate the miniaturization of an enzymatic assay for the determination of NADH oxidation and quinone reduction by the Na+ -translocating NADH quinone oxidoreductase (NQR) in the 96-well plate format. The assay is based on the spectrophotometr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f50bea22017b605239fc6313c65a735c
https://doi.org/10.1016/j.ab.2017.08.025
https://doi.org/10.1016/j.ab.2017.08.025
Autor:
Hamid R. Nasiri, Katharina F. Hohmann, Harald Schwalbe, Melissa G. Hatemler, Franz Bracher, Alois Plodek
Publikováno v:
Medicinal Chemistry Research. 26:1170-1175
Sampangine is an azaoxoaporphine alkaloid with interesting biological activities. Elucidating the mode of action of sampangine is a topic of continuous research. Recently reported cell-based data have indicated heme-dysfunction and subsequent reactiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c75a1d804660dba6848b1caa9baf8bf
https://doi.org/10.1007/s00044-017-1835-8
https://doi.org/10.1007/s00044-017-1835-8
Publikováno v:
MedChemComm. 8:657-661
By probing the quinone substrate binding site of mitochondrial complex I with a focused set of quinazoline-based compounds, we identified substitution patterns as being critical for the observed inhibition. The structure activity relationship study a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::510be9453ed19223173b9c745fe0025b
https://doi.org/10.1039/c6md00655h
https://doi.org/10.1039/c6md00655h
Publikováno v:
MedChemComm. 7:1421-1428
Doramapimod (BIRB 796) is a potent inhibitor of p38α mitogen-activated protein kinase. It contains an aryl-pyrazole scaffold as a pharmacophore critical for binding. The aryl-pyrazole scaffold is not planar and adopts an out-of-plane conformation, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a639c2ee472ccd9df8f7b79feb3f4bb
https://doi.org/10.1039/c6md00262e
https://doi.org/10.1039/c6md00262e