Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Hamid Irannejad"'
Autor:
Mehdi Valipour, Zahra Zakeri, Kaveh Kiadaliry, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Mohammad Shokati Sayyad, Mohammad Seyedabadi, Majid Ghasemian, Seyedeh Mahdieh Hashemi, Hamid Irannejad
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 12, Iss , Pp 100207- (2024)
Type 2 diabetes is a common condition that causes the level of glucose in the blood to become too high and α-glucosidase inhibitors are therapeutic agents in managing type 2 diabetes. In the present study, we report a new series of 3-aceto(benzo)hyd
Externí odkaz:
https://doaj.org/article/3a15142535f74b009bfc0fa2c9c502f6
Autor:
Esmaeil Roohparvar Basmenj, Mahshid Arastonejad, Mina Mamizadeh, Mahsa Alem, Mahdi KhalatbariLimaki, Shadan Ghiabi, Ali Khamesipour, Hamidreza Majidiani, Morteza Shams, Hamid Irannejad
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Cutaneous leishmaniasis (CL) is a very common parasitic infection in subtropical areas worldwide. Throughout decades, there have been challenges in vaccine design and vaccination against CL. The present study introduced novel T-cell-based va
Externí odkaz:
https://doaj.org/article/e0fbbfcc1fa843bc97ee15cc00c064fc
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2619 (2023)
Ongoing viral research, essential for public health due to evolving viruses, gains significance owing to emerging viral infections such as the SARS-CoV-2 pandemic. Marine and plant alkaloids show promise as novel potential pharmacological strategies.
Externí odkaz:
https://doaj.org/article/8f20a29974944b8b92f975d3654b8edb
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8789 (2023)
Previous studies indicated that natural-based chalcones have significant inhibitory effects on the coronavirus enzymes 3CLpro and PLpro as well as modulation of some host-based antiviral targets (HBATs). In this study, a comprehensive computational a
Externí odkaz:
https://doaj.org/article/b59aeb6a86644944bcf644a5026de0a1
Autor:
Mehdi Valipour, Hamid Irannejad
Publikováno v:
Journal of Mazandaran University of Medical Sciences, Vol 29, Iss 172, Pp 188-206 (2019)
Epilepsy is a neurological condition characterized by recurrent seizures influencing about 1% of the worldwide population. Despite much progress in understanding the pathogenesis of epilepsy, the molecular basis of human epilepsy still remains unclea
Externí odkaz:
https://doaj.org/article/df433be6273849faaddff7fa2ba1a75a
Autor:
Morteza Shams, Hassan Nourmohammadi, Ali Asghari, Gholam Basati, Hamidreza Majidiani, Razi Naserifar, Hamid Irannejad
Publikováno v:
Informatics in Medicine Unlocked, Vol 26, Iss , Pp 100732- (2021)
Toxocariasis is a global public health concern, particularly in children. Serological diagnosis of the infection is routinely applied to detect specific anti-Toxocara antibodies. Current in silico study was contrived to design a multi-epitope protein
Externí odkaz:
https://doaj.org/article/f76e4fab0e2046cd91511e7ac0d1b385
Publikováno v:
Data in Brief, Vol 31, Iss , Pp 105942- (2020)
The data have been obtained for tautomers and enantiomers of ATTAF-1 and ATTAF-2 that were developed based on antifungal standard drugs with triazole scaffold. These compounds were docked into the human and fungal lanosterol-14α-demethylase. In orde
Externí odkaz:
https://doaj.org/article/de53d00f2024482fa35deffd51e0b98f
Autor:
Hassan Nourmohammadi, Erfan Javanmardi, Morteza Shams, Sadegh Shamsinia, Mohammadreza Chaechi Nosrati, Ali Yousefi, Taher Nemati, Mohammad Fatollahzadeh, Ezatollah Ghasemi, Bahareh Kordi, Hamidreza Majidiani, Hamid Irannejad
Publikováno v:
Informatics in Medicine Unlocked, Vol 21, Iss , Pp 100464- (2020)
Cystic echinococcosis (CE) is a near-cosmopolitan public health concern, especially in developing countries. Parasite ova shed via definitive host feces are responsible for livestock and occasionally human infection, leading to hydatid cysts. Immuniz
Externí odkaz:
https://doaj.org/article/06cdd4c9bcc64855bdf90d4847abbf0f
Publikováno v:
Informatics in Medicine Unlocked, Vol 20, Iss , Pp 100366- (2020)
The emergence of resistance to azole drugs, presented significant problems for medicine that could be overcome by advances in antifungal design. We convinced that the crystal structures of fungal and host lanosterol-14α-demethylases in complex with
Externí odkaz:
https://doaj.org/article/3d01584eb57a4f03868293341d1055b7
Autor:
Antonella Di Sotto, Hamid Irannejad, Margherita Eufemi, Romina Mancinelli, Lorena Abete, Caterina Loredana Mammola, Fabio Altieri, Gabriela Mazzanti, Silvia Di Giacomo
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 2, p 633 (2020)
Doxorubicin represents a valuable choice for different cancers, although the severe side effects occurring at the high effective dose limits its clinical use. In the present study, potential strategies to potentiate low-dose doxorubicin efficacy, inc
Externí odkaz:
https://doaj.org/article/378dbeb9821e4036b5a64c729e59e274