Zobrazeno 1 - 10
of 286
pro vyhledávání: '"Hamid Band"'
Autor:
Aaqib M. Bhat, Bhopal C. Mohapatra, Haitao Luan, Insha Mushtaq, Sukanya Chakraborty, Siddhartha Kumar, Wangbin Wu, Ben Nolan, Samikshan Dutta, Matthew D. Storck, Micah Schott, Jane L. Meza, Subodh M. Lele, Ming-Fong Lin, Leah M. Cook, Eva Corey, Colm Morrissey, Donald W. Coulter, M. Jordan Rowley, Amarnath Natarajan, Kaustubh Datta, Vimla Band, Hamid Band
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract While better management of loco-regional prostate cancer (PC) has greatly improved survival, advanced PC remains a major cause of cancer deaths. Identification of novel targetable pathways that contribute to tumor progression in PC could ope
Externí odkaz:
https://doaj.org/article/5e1271695c79456bb92777ad45c70f97
Autor:
Neha Zutshi, Bhopal C. Mohapatra, Pinaki Mondal, Wei An, Benjamin T. Goetz, Shuo Wang, Sicong Li, Matthew D. Storck, David F. Mercer, Adrian R. Black, Sarah P. Thayer, Jennifer D. Black, Chi Lin, Vimla Band, Hamid Band
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109912- (2024)
Summary: Receptor tyrosine kinases (RTKs) control stem cell maintenance vs. differentiation decisions. Casitas B-lineage lymphoma (CBL) family ubiquitin ligases are negative regulators of RTKs, but their stem cell regulatory roles remain unclear. Her
Externí odkaz:
https://doaj.org/article/768c3a8058a948e9abfe75334d310948
Autor:
Winnie G. Vos, Bram W. van Os, Myrthe den Toom, Linda Beckers, Cindy P.A.A. van Roomen, Claudia M. van Tiel, Bhopal C. Mohapatra, Hamid Band, Katrin Nitz, Christian Weber, Dorothee Atzler, Menno P.J. de Winther, Laura A. Bosmans, Esther Lutgens, Tom T.P. Seijkens
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAtherosclerosis is a lipid-driven inflammatory disease of the arterial wall, and the underlying cause of the majority of cardiovascular diseases. Recent advances in high-parametric immunophenotyping of immune cells indicate that T cells c
Externí odkaz:
https://doaj.org/article/17ccf05dbe754c14b60fa4b6e02d7e09
Autor:
Conor M. Henry, Carlos A. Castellanos, Michael D. Buck, Evangelos Giampazolias, Bruno Frederico, Ana Cardoso, Neil C. Rogers, Oliver Schulz, Sonia Lee, Johnathan Canton, Peter Faull, Ambrosius P. Snijders, Bhopal Mohapatra, Hamid Band, Caetano Reis e Sousa
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113506- (2023)
Summary: Cross-presentation of dead cell-associated antigens by conventional dendritic cells type 1 (cDC1s) is critical for CD8+ T cells response against many tumors and viral infections. It is facilitated by DNGR-1 (CLEC9A), an SYK-coupled cDC1 rece
Externí odkaz:
https://doaj.org/article/f17e0bebdccf4243bbe20ce69f73d27f
Autor:
Sukanya Chakraborty, Aaqib M. Bhat, Insha Mushtaq, Haitao Luan, Achyuth Kalluchi, Sameer Mirza, Matthew D. Storck, Nagendra Chaturvedi, Jose Antonio Lopez-Guerrero, Antonio Llombart-Bosch, Isidro Machado, Katia Scotlandi, Jane L. Meza, Gargi Ghosal, Donald W. Coulter, M. Jordan Rowley, Vimla Band, Bhopal C. Mohapatra, Hamid Band
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-21 (2023)
Abstract Overexpression of the EPS15 Homology Domain containing 1 (EHD1) protein has been linked to tumorigenesis but whether its core function as a regulator of intracellular traffic of cell surface receptors plays a role in oncogenesis remains unkn
Externí odkaz:
https://doaj.org/article/09e76c7a25c7457f98d7a6fdc6e884ba
Autor:
Haitao Luan, Timothy A Bielecki, Bhopal C Mohapatra, Namista Islam, Insha Mushtaq, Aaqib M Bhat, Sameer Mirza, Sukanya Chakraborty, Mohsin Raza, Matthew D Storck, Michael S Toss, Jane L Meza, Wallace B Thoreson, Donald W Coulter, Emad A Rakha, Vimla Band, Hamid Band
Publikováno v:
eLife, Vol 12 (2023)
With nearly all cancer deaths a result of metastasis, elucidating novel pro-metastatic cellular adaptations could provide new therapeutic targets. Here, we show that overexpression of the EPS15-Homology Domain-containing 2 (EHD2) protein in a large s
Externí odkaz:
https://doaj.org/article/eac71e4f84fb43cd93ba5835547b1360
Autor:
Haitao Luan, Tameka A. Bailey, Robert J. Clubb, Bhopal C. Mohapatra, Aaqib M. Bhat, Sukanya Chakraborty, Namista Islam, Insha Mushtaq, Matthew D. Storck, Srikumar M. Raja, Vimla Band, Hamid Band
Publikováno v:
Cancers, Vol 13, Iss 16, p 3936 (2021)
Overexpression of the epidermal growth factor receptor (EGFR) family member ErbB2 (HER2) drives oncogenesis in up to 25% of invasive breast cancers. ErbB2 expression at the cell surface is required for oncogenesis but mechanisms that ensure the optim
Externí odkaz:
https://doaj.org/article/c0f18ebf17a04c0aa1b85f09bcc9bdc7
Autor:
Nicholas P. Schafer, Riyaz A. Mir, Jeff Lovelace, Peter D. Simone, Admir Kellezi, Carol Kolar, Gaelle Spagnol, Paul L. Sorgen, Hamid Band, Vimla Band, Gloria E. O. Borgstahl
Publikováno v:
AIMS Biophysics, Vol 3, Iss 1, Pp 195-210 (2016)
The human homolog of Drosophila ecdysoneless protein (ECD) is a p53 binding protein that stabilizes and enhances p53 functions. Homozygous deletion of mouse Ecd is early embryonic lethal and Ecd deletion delays G1-S cell cycle progression. Importantl
Externí odkaz:
https://doaj.org/article/783855f100574a31999623b0380c8c6c
Autor:
Virginie Buggia-Prévot, Celia G. Fernandez, Vinod Udayar, Kulandaivelu S. Vetrivel, Aureliane Elie, Jelita Roseman, Verena A. Sasse, Margaret Lefkow, Xavier Meckler, Sohinee Bhattacharyya, Manju George, Satyabrata Kar, Vytautas P. Bindokas, Angèle T. Parent, Lawrence Rajendran, Hamid Band, Robert Vassar, Gopal Thinakaran
Publikováno v:
Cell Reports, Vol 5, Iss 6, Pp 1552-1563 (2013)
Abnormal accumulation of β-secretase (BACE1) in dystrophic neurites and presynaptic β-amyloid (Aβ) production contribute to Alzheimer's disease pathogenesis. Little, however, is known about BACE1 sorting and dynamic transport in neurons. We invest
Externí odkaz:
https://doaj.org/article/e70f233a87f94bd6a3bb327d19e60a61
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167064 (2016)
Breast cancer is characterized into different molecular subtypes, and each subtype is characterized by differential gene expression that are associated with distinct survival outcomes in patients. PIK3CA mutations are commonly associated with most br
Externí odkaz:
https://doaj.org/article/df6b699fced2408ab66e7c3eb631fc5c