Innovation of 6-sulfonamide-2 H -chromene derivatives as antidiabetic agents targeting α-amylase, α-glycosidase, and PPAR-γ inhibitors with in silico molecular docking simulation.

Autor: Thabet HK; Department of Chemistry, College of Sciences and Arts, Northern Border University Rafha 91911 Saudi Arabia Hamdy.salem@nbu.edu.sa., Ragab A; Department of Chemistry, Faculty of Science (Boys), Al-Azhar University Nasr City 11884 Cairo Egypt ahmed_ragab@azhar.edu.eg Ahmed_ragab7@ymail.com., Imran M; Department of Pharmaceutical Chemistry, College of Pharmacy, Northern Border University Rafha 91911 Saudi Arabia., Hamdy Helal M; Department of Chemistry, College of Sciences and Arts, Northern Border University Rafha 91911 Saudi Arabia Hamdy.salem@nbu.edu.sa., Ibrahim Alaqel S; Department of Pharmaceutical Chemistry, College of Pharmacy, Northern Border University Rafha 91911 Saudi Arabia., Alshehri A; Department of Pharmacology and Toxicology, College of Pharmacy, Northern Border University Rafha 91911 Saudi Arabia.; Department of Pharmacology, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University King Faisal Road Dammam 31441 Saudi Arabia., Ash Mohd A; Department of Pharmaceutical Chemistry, College of Pharmacy, Northern Border University Rafha 91911 Saudi Arabia., Alshammari SS; Department of Chemistry, College of Sciences and Arts, Northern Border University Rafha 91911 Saudi Arabia Hamdy.salem@nbu.edu.sa., Ammar YA; Department of Chemistry, Faculty of Science (Boys), Al-Azhar University Nasr City 11884 Cairo Egypt ahmed_ragab@azhar.edu.eg Ahmed_ragab7@ymail.com., Abusaif MS; Department of Chemistry, Faculty of Science (Boys), Al-Azhar University Nasr City 11884 Cairo Egypt ahmed_ragab@azhar.edu.eg Ahmed_ragab7@ymail.com.

Publikováno v: RSC advances [RSC Adv] 2024 May 14; Vol. 14 (22), pp. 15691-15705. Date of Electronic Publication: 2024 May 14 (Print Publication: 2024).