Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hamdi Joda"'
Autor:
Angel E. Kaifer, Angeliki Moutsiopoulou, David Broyles, Emre Dikici, Hamdi Joda, Sylvia Daunert, Avinash Kaur, Sapna K. Deo
Publikováno v:
Anal Chem
Although bioluminescent molecular beacons designed around resonance quenchers have shown higher signal-to-noise ratios and increased sensitivity compared with fluorescent beacon systems, bioluminescence quenching is still comparatively inefficient. A
Publikováno v:
The Analyst. 143:3374-3381
Here we describe the design of a bioluminescent stem-loop probe for the sensitive detection of HIV-1 spliced RNA. In this study, we employed Gaussia luciferase (GLuc), a bioluminescent protein that has several advantages over other bioluminescent pro
Publikováno v:
Electrochimica Acta. 220:581-586
We report the development of a “sandwich-hybridization” electrochemical DNA-detection assay on gold electrodes using osmium tetroxide-labeled reporter strands, while avoiding chemical modification of analyte strands. Successful design of the olig
Publikováno v:
Electroanalysis. 29:51-59
Osmium tetroxide bipyridine ([OsO4(bpy)]) is a versatile label for DNA electrochemistry. Here we report our efforts to create an osmium tetroxide-labeled immobilized DNA probe for use in biosensing experiments. Our label is applied in-house, as oppos
Autor:
Josep Ll. Acero Sánchez, Guillaume Suarez, Ciara K. O'Sullivan, Hamdi Joda, Alex Fragoso, Calum J. McNeil
Publikováno v:
Analytical and Bioanalytical Chemistry. 408:5337-5346
The interface between the sample and the transducer surface is critical to the performance of a biosensor. In this work, we compared different strategies for covalent self-assembly of antibodies onto bare gold substrates by introducing disulfide grou
Autor:
Miriam Jauset-Rubio, Mayreli Ortiz, Ioanis Katakis, Hamdi Joda, Sallam Al-Madhagi, Ciara K. O'Sullivan
Publikováno v:
Analytical biochemistry. 556
DNA biosensors are attractive tools for genetic analysis as there is an increasing need for rapid and low-cost DNA analysis, primarily driven by applications in personalized pharmacogenomics, clinical diagnostics, rapid pathogen detection, food trace
Autor:
Julian Höth, Ciara K. O'Sullivan, Richard Klemm, Kristina Lind, Hamdi Joda, Alex Fragoso, Valerio Beni, Mayreli Ortiz, Ioanis Katakis
Publikováno v:
ELECTROPHORESIS. 36:1920-1926
Celiac disease is an auto-immune disorder induced by ingestion of gluten in genetically predisposed individuals. Its diagnostics is more accurate using a combination of immunologic and genetic tests to detect of high levels of certain auto-antibodies
Autor:
Ian Riley, Linda Kvastad, Carmen Schwind, Daniel Latta, Joakim Lundeberg, Nadja Laddach, Ciara K. O'Sullivan, Josep Ll. Acero Sánchez, Beata Werne Solnestam, Pelin Akan, Olivier Y.F. Henry, Hamdi Joda, Dheeraj Ramakrishnan
Publikováno v:
Analytical chemistry. 89(6)
Recent understandings in the development and spread of cancer have led to the realization of novel single cell analysis platforms focused on circulating tumor cells (CTCs). A simple, rapid, and inexpensive analytical platform capable of providing gen
Autor:
Jukka Partanen, Hamdi Joda, Daniel Latta, Ciara K. O'Sullivan, Noora Alakulppi, Valerio Beni, Kristina Lind, Ioanis Katakis, Linda Strömbom, Julian Höth
Publikováno v:
Analytical and Bioanalytical Chemistry. 406:2757-2769
Coeliac disease is a small intestinal disorder, induced by ingestion of gluten in genetically predisposed individuals. Coeliac disease has been strongly linked to human leukocyte antigens (HLA) located on chromosome 6, with almost 100 % of coeliac di
Publikováno v:
Analytical Biochemistry. 474:66-68
We report on a simple approach to enhance solid-phase hybridization-based single base mismatch discrimination at high ionic strength based on the deliberate insertion of a natural DNA base mismatch in the surface-tethered probe. A large drop in hybri