Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Hamanaka, Ernest S."'
Autor:
H. James Harwood, Hamanaka Ernest S
Publikováno v:
Emerging Drugs. 3:147-172
Coronary heart disease (CHD) is the leading cause of morbidity and mortality in most developed nations and atherosclerotic cardiovascular disease accounts for approximately one-half of all deaths due to CHD. Dyslipidaemias, which include various comb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df7cc76904756ec1544741997dd773bb
https://doi.org/10.1517/14728214.3.1.147
https://doi.org/10.1517/14728214.3.1.147
Autor:
B. J. Gaynor, C. L. Diaz, D. I. Goldberg, T. G. Lacour, M. J. Bamberger, M. E. Maloney, A. M. Freeman, Philip B. Inskeep, K. M. Davis, Walker Frederick J, D. A. Johnson, Carol A. Marzetta, J. T. Mayne, Yvette E. Savoy, Sarah E. Kelly, C A Long, Hamanaka Ernest S, T. A. Beyer, George Chang, Mccarthy Peter A
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77b790ec407c48419e9ed4af6da0c8ec
https://doi.org/10.1002/chin.199435170
https://doi.org/10.1002/chin.199435170
Autor:
John G. Stam, Paul R. Kelbaugh, John Jasys, Thomas Gootz, Dennis Girard, Thomas G. Tensfeldt, Benedict Campbell, William Schelkley, Robert A. Volkmann, George H Foulds, Michael S. Kellogg, Hamanaka Ernest S
Publikováno v:
The Journal of Antibiotics. 43:422-432
The pharmacokinetics of penem CP-65,207 diastereomeric mixture were studied following parenteral administration in mice, rats, beagle dogs and cynomolgus monkeys. As is characteristic for most penems, the serum elimination T1/2 of CP-65,207 in rodent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b51689077f658642c8b06e23e540c5f1
https://doi.org/10.7164/antibiotics.43.422
https://doi.org/10.7164/antibiotics.43.422
Autor:
W. Ross Tracey, Hamanaka Ernest S, Roger J. Hill, Ravi B. Marala, Delvin R. Knight, Jimmy Kong, Dexue Sun, Wester Ronald Thure, Janice A. Brown, Roger B. Ruggeri, Scott P. Kennedy
Publikováno v:
European journal of pharmacology. 451(1)
We evaluated the in vitro pharmacological profile of a novel, potent and highly selective Na(+)/H(+) exchanger-1 (NHE-1) inhibitor, [1-(Quinolin-5-yl)-5-cyclopropyl-1H-pyrazole-4-carbonyl]guanidine hydrochloride monohydrate (zoniporide or CP-597,396)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e152230e5a4603224b4e9140d07023c8
https://pubmed.ncbi.nlm.nih.gov/12223226
https://pubmed.ncbi.nlm.nih.gov/12223226
Autor:
Ravi B. Marala, Allan R. Buchholz, Delvin R. Knight, Scott P. Kennedy, Wester Ronald Thure, Paul J. Kowalczyk, Roger J. Hill, Roger B. Ruggeri, Angel Guzman-Perez, Ewell R. Cook, Mary C. Allen, Day Wesley Warren, Janice A. Brown, Mularski Christian J, William Albert Novomisle, W. Ross Tracey, Hamanaka Ernest S
Publikováno v:
Bioorganicmedicinal chemistry letters. 11(6)
Zoniporide (CP-597,396) is a potent and selective inhibitor of NHE-1, which exhibits high aqueous solubility and acceptable pharmacokinetics for intravenous administration. The discovery, synthesis, activities, and rat and dog pharmacokinetics of thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ab46b1bc912c815842109bc5bf21715
https://pubmed.ncbi.nlm.nih.gov/11277524
https://pubmed.ncbi.nlm.nih.gov/11277524
Autor:
Guzman-Perez, Angel, Wester, Ronald T., Allen, Mary C., Brown, Janice A., Buchholz, Allan R., Cook, Ewell R., Day, Wesley W., Hamanaka, Ernest S., Kennedy, Scott P., Knight, Delvin R., Kowalczyk, Paul J., Marala, Ravi B., Mularski, Christian J., Novomisle, William A., Ruggeri, Roger B., Tracey, W.Ross, Hill, Roger J.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 2001 11(6):803-807
Publikováno v:
Tetrahedron Letters. 15:1515-1518
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4167bf321a0db9ae326e9af406253d9
https://doi.org/10.1016/s0040-4039(01)93124-7
https://doi.org/10.1016/s0040-4039(01)93124-7
Publikováno v:
Tetrahedron Letters. 20:4631-4634
Reduction of 6-substituted-6-halopenicillanates with tri-n-butyltin hydride can produce stereoselectively 6β-substituted derivatives.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2592df1f359b7abaf1deeb776657ee2a
https://doi.org/10.1016/s0040-4039(01)86668-5
https://doi.org/10.1016/s0040-4039(01)86668-5
Autor:
Pandit, Jayvardhan, Danley, Dennis E., Schulte, Gayle K., Mazzalupo, Stacy, Pauly, Thomas A., Hayward, Cheryl M., Hamanaka, Ernest S., Thompson, John F., Harwood, H. James
Publikováno v:
Journal of Biological Chemistry; September 2000, Vol. 275 Issue: 39 p30610-30617, 8p
Publikováno v:
Expert Opinion on Emerging Drugs; June 1998, Vol. 3 Issue: 1 p147-172, 26p