Urate transport in health and disease.

Autor: Halperin Kuhns VL; Department of Physiology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA. Electronic address: vhalperin-kuhns@som.umaryland.edu., Woodward OM; Department of Physiology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA. Electronic address: OWoodward@som.umaryland.edu.

Publikováno v: Best practice & research. Clinical rheumatology [Best Pract Res Clin Rheumatol] 2021 Dec; Vol. 35 (4), pp. 101717. Date of Electronic Publication: 2021 Oct 21.

Sex Differences in Urate Handling.

Autor: Halperin Kuhns VL; Department of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Woodward OM; Department of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2020 Jun 16; Vol. 21 (12). Date of Electronic Publication: 2020 Jun 16.

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.

Autor: Tin A; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. atin1@jhu.edu.; Welch Centre for Prevention, Epidemiology and Clinical Research, Baltimore, MD, USA. atin1@jhu.edu., Marten J; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Halperin Kuhns VL; Department of Physiology, University of Maryland School of Medicine, Baltimore, MD, USA., Li Y; Institute of Genetic Epidemiology, Department of Biometry, Epidemiology and Medical Bioinformatics, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany., Wuttke M; Institute of Genetic Epidemiology, Department of Biometry, Epidemiology and Medical Bioinformatics, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany., Kirsten H; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE Research Centre for Civilization Diseases, University of Leipzig, Leipzig, Germany., Sieber KB; Target Sciences-Genetics, GlaxoSmithKline, Collegeville, PA, USA., Qiu C; Department of Medicine and Genetics, University of Pennsylvania, Philadelphia, PA, USA., Gorski M; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Yu Z; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Giri A; Division of Quantitative Sciences, Department of Obstetrics & Gynecology, Vanderbilt Genetics Institute, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt University Medical Center, Nashville, TN, USA.; Biomedical Laboratory Research and Development, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Sveinbjornsson G; deCODE Genetics, Amgen Inc., Reykjavik, Iceland., Li M; Department of Medicine, Division of Nephrology and Hypertension, University of Utah, Salt Lake City, UT, USA., Chu AY; Genetics, Merck & Co., Inc, Kenilworth, NJ, USA., Hoppmann A; Institute of Genetic Epidemiology, Department of Biometry, Epidemiology and Medical Bioinformatics, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany., O'Connor LJ; Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Prins B; Strangeways Research Laboratory, University of Cambridge, Cambridge, UK., Nutile T; Institute of Genetics and Biophysics Adriano Buzzati-Traverso-CNR, Naples, Italy., Noce D; Eurac Research, Institute for Biomedicine, Bolzano, Italy., Akiyama M; Laboratory for Statistical Analysis, RIKEN Centre for Integrative Medical Sciences, Yokohama (Kanagawa), Japan.; Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Cocca M; Institute for Maternal and Child Health-IRCCS Burlo Garofolo, Trieste, Italy., Ghasemi S; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Horn K; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE Research Centre for Civilization Diseases, University of Leipzig, Leipzig, Germany., Xu Y; Department of Medicine, Division of Nephrology and Hypertension, University of Utah, Salt Lake City, UT, USA., Fuchsberger C; Eurac Research, Institute for Biomedicine, Bolzano, Italy., Sedaghat S; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Afaq S; Department of Epidemiology and Biostatistics, Faculty of Medicine, School of Public Health, Imperial College London, London, UK.; Institute of Public Health & Social Sciences, Khyber Medical University, Peshawar, Pakistan., Amin N; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Ärnlöv J; Department of Neurobiology, Care Sciences and Society, Division of Family Medicine and Primary Care, Karolinska Institutet, Stockholm, Sweden.; School of Health and Social Studies, Dalarna University, Falun, Sweden., Bakker SJL; Department of Internal Medicine, Division of Nephrology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Bansal N; Division of Nephrology, University of Washington, Seattle, WA, USA.; Kidney Research Institute, University of Washington, Seattle, WA, USA., Baptista D; Cardiology, Geneva University Hospitals, Geneva, Switzerland., Bergmann S; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Department of Integrative Biomedical Sciences, University of Cape Town, Cape Town, South Africa., Biggs ML; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Biostatistics, University of Washington, Seattle, WA, USA., Biino G; Institute of Molecular Genetics, National Research Council of Italy, Pavia, Italy., Boerwinkle E; Human Genetics Centre, University of Texas Health Science Centre, Houston, TX, USA., Bottinger EP; Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Boutin TS; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Brumat M; University of Trieste, Department of Medicine, Surgery and Health Sciences, Trieste, Italy., Burkhardt R; LIFE Research Centre for Civilization Diseases, University of Leipzig, Leipzig, Germany.; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University of Leipzig, Leipzig, Germany.; Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Regensburg, Germany., Campana E; University of Trieste, Department of Medicine, Surgery and Health Sciences, Trieste, Italy., Campbell A; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Campbell H; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Carroll RJ; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA., Catamo E; Institute for Maternal and Child Health-IRCCS Burlo Garofolo, Trieste, Italy., Chambers JC; Department of Epidemiology and Biostatistics, Faculty of Medicine, School of Public Health, Imperial College London, London, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Department of Cardiology, Ealing Hospital, London, UK.; Imperial College Healthcare NHS Trust, Imperial College London, London, UK.; MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Ciullo M; Institute of Genetics and Biophysics Adriano Buzzati-Traverso-CNR, Naples, Italy.; IRCCS Neuromed, Pozzilli, Italy., Concas MP; Institute for Maternal and Child Health-IRCCS Burlo Garofolo, Trieste, Italy., Coresh J; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Corre T; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland., Cusi D; Institute of Biomedical Technologies, Italy National Research Council, Milano, Italy.; Bio4Dreams, Milano, Italy., Felicita SC; San Raffaele Research Institute, Milano, Italy., de Borst MH; Department of Internal Medicine, Division of Nephrology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., De Grandi A; Eurac Research, Institute for Biomedicine, Bolzano, Italy., de Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Centre, Leiden, the Netherlands., de Vries APJ; Section of Nephrology, Department of Internal Medicine, Leiden University Medical Centre, Leiden, the Netherlands., Delgado G; Fifth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Demirkan A; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Genetics, University Medical Center Groningen, Groningen, the Netherlands., Devuyst O; Institute of Physiology, University of Zurich, Zurich, Switzerland., Dittrich K; Department of Women and Child Health, Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany.; Centre for Pediatric Research, University of Leipzig, Leipzig, Germany., Eckardt KU; Department of Nephrology and Medical Intensive Care, Charité-Universitätsmedizin Berlin, Berlin, Germany.; Department of Nephrology and Hypertension, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany., Ehret G; Cardiology, Geneva University Hospitals, Geneva, Switzerland., Endlich K; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany.; Department of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald, Germany., Evans MK; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, National Institutes of Health, Baltimore, MD, USA., Gansevoort RT; Department of Internal Medicine, Division of Nephrology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Gasparini P; Institute for Maternal and Child Health-IRCCS Burlo Garofolo, Trieste, Italy.; University of Trieste, Department of Medicine, Surgery and Health Sciences, Trieste, Italy., Giedraitis V; Department of Public Health and Caring Sciences, Molecular Geriatrics, Uppsala University, Uppsala, Sweden., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Centre for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München-German Research Centre for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Girotto G; Institute for Maternal and Child Health-IRCCS Burlo Garofolo, Trieste, Italy.; University of Trieste, Department of Medicine, Surgery and Health Sciences, Trieste, Italy., Gögele M; Eurac Research, Institute for Biomedicine, Bolzano, Italy., Gordon SD; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Gudbjartsson DF; deCODE Genetics, Amgen Inc., Reykjavik, Iceland., Gudnason V; Icelandic Heart Association, Kópavogur, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland., Haller T; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Hamet P; Montreal University Hospital Research Centre, Centre Hospitalier de lUniversité de Montréal, Montreal, Quebec, Canada.; Medpharmgene, Montreal, Quebec, Canada., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, National Institutes of Health, Bethesda, MD, USA., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Hicks AA; Eurac Research, Institute for Biomedicine, Bolzano, Italy., Hofer E; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria.; Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria., Holm H; deCODE Genetics, Amgen Inc., Reykjavik, Iceland., Huang W; Department of Genetics, Shanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Centre, Shanghai, China.; Shanghai Industrial Technology Institute, Shanghai, China., Hutri-Kähönen N; Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Department of Pediatrics, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Hwang SJ; National Heart, Lung, and Blood Institute Framingham Heart Study, Framingham, MA, USA.; The Centre for Population Studies, National Heart, Lung, and Blood Institute, Framingham, MA, USA., Ikram MA; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Lewis RM; Department of Physiology, University of Maryland School of Medicine, Baltimore, MD, USA., Ingelsson E; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA.; Molecular Epidemiology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.; Stanford Diabetes Research Center, Stanford University, Stanford, CA, USA., Jakobsdottir J; Icelandic Heart Association, Kópavogur, Iceland.; The Centre of Public Health Sciences, University of Iceland, Reykjavik, Iceland., Jonsdottir I; deCODE Genetics, Amgen Inc., Reykjavik, Iceland., Jonsson H; Landspitalinn University Hospital, Reykjavík, Iceland.; University of Iceland, Reykjavík, Iceland., Joshi PK; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Josyula NS; Geisinger Research, Biomedical and Translational Informatics Institute, Rockville, MD, USA., Jung B; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, and Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Kamatani Y; Laboratory for Statistical Analysis, RIKEN Centre for Integrative Medical Sciences, Yokohama (Kanagawa), Japan.; Kyoto-McGill International Collaborative School in Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan., Kanai M; Laboratory for Statistical Analysis, RIKEN Centre for Integrative Medical Sciences, Yokohama (Kanagawa), Japan.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Kerr SM; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Kiess W; LIFE Research Centre for Civilization Diseases, University of Leipzig, Leipzig, Germany.; Department of Women and Child Health, Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany.; Centre for Pediatric Research, University of Leipzig, Leipzig, Germany., Kleber ME; Fifth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Koenig W; Deutsches Herzzentrum München, Technische Universität München, Munich, Germany.; German Centre for Cardiovascular Research, Partner Site Munich Heart Alliance, Munich, Germany.; Institute of Epidemiology and Biostatistics, University of Ulm, Ulm, Germany., Kooner JS; Department of Cardiology, Ealing Hospital, London, UK.; Imperial College Healthcare NHS Trust, Imperial College London, London, UK.; MRC-PHE Centre for Environment and Health, 323 School of Public Health, Imperial College London, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK., Körner A; LIFE Research Centre for Civilization Diseases, University of Leipzig, Leipzig, Germany.; Department of Women and Child Health, Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany.; Centre for Pediatric Research, University of Leipzig, Leipzig, Germany., Kovacs P; Integrated Research and Treatment Centre Adiposity Diseases, University of Leipzig, Leipzig, Germany., Krämer BK; Fifth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Kronenberg F; Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Medical University of Innsbruck, Innsbruck, Austria., Kubo M; RIKEN Centre for Integrative Medical Sciences, Yokohama (Kanagawa), Japan., Kühnel B; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Centre for Environmental Health, Neuherberg, Germany., La Bianca M; Institute for Maternal and Child Health-IRCCS Burlo Garofolo, Trieste, Italy., Lange LA; Division of Biomedical Informatics and Personalized Medicine, School of Medicine, University of Colorado Denver-Anschutz Medical Campus, Aurora, CO, USA., Lehne B; Department of Epidemiology and Biostatistics, Faculty of Medicine, School of Public Health, Imperial College London, London, UK., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Liu J; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Loeffler M; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE Research Centre for Civilization Diseases, University of Leipzig, Leipzig, Germany., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Magi R; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., März W; Fifth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.; Synlab Academy, Synlab Holding Deutschland GmbH, Mannheim, Germany.; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria., Mascalzoni D; Eurac Research, Institute for Biomedicine, Bolzano, Italy., Matsuda K; Laboratory of Clinical Genome Sequencing, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan., Meisinger C; Independent Research Group Clinical Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany.; Ludwig-Maximilians-Universität München at UNIKA-T Augsburg, Augsburg, Germany., Meitinger T; German Centre for Cardiovascular Research, Partner Site Munich Heart Alliance, Munich, Germany.; Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany.; Institute of Human Genetics, Technische Universität München, Munich, Germany., Metspalu A; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Milaneschi Y; Department of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, Amsterdam University Medical Centers, Amsterdam, the Netherlands., O'Donnell CJ; VA Boston Healthcare System, Boston, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Wilson OD; Vanderbilt University Medical Centre, Division of Nephrology & Hypertension, Nashville, TN, USA., Gaziano JM; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Massachusetts Veterans Epidemiology Research and Information Center, VA Cooperative Studies Program, VA Boston Healthcare System, Boston, MA, USA., Mishra PP; Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Mononen N; Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Montgomery GW; University of Queensland, St Lucia, Queensland, Australia., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Centre, Leiden, the Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Centre, Leiden, the Netherlands., Müller-Nurasyid M; German Centre for Cardiovascular Research, Partner Site Munich Heart Alliance, Munich, Germany.; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Centre for Environmental Health, Neuherberg, Germany.; Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU Munich, Munich, Germany.; Department of Internal Medicine I (Cardiology), Hospital of the Ludwig-Maximilians-University Munich, Munich, Germany., Nadkarni GN; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Nalls MA; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.; Data Tecnica International, Glen Echo, MD, USA., Nauck M; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany.; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany., Nikus K; Department of Cardiology, Heart Center, Tampere University Hospital, Tampere, Finland.; Department of Cardiology, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Ning B; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Noordam R; Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Centre, Leiden, the Netherlands., O'Connell JR; University of Maryland School of Medicine, Baltimore, MD, USA., Olafsson I; Department of Clinical Biochemistry, Landspitali University Hospital, Reykjavik, Iceland., Padmanabhan S; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK., Penninx BWJH; Department of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, Amsterdam University Medical Centers, Amsterdam, the Netherlands., Perls T; Department of Medicine, Geriatrics Section, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA., Peters A; Institute of Epidemiology, Helmholtz Zentrum München-German Research Centre for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research, Neuherberg, Germany.; German Centre for Cardiovascular Research, Partner Site Munich Heart Alliance, Munich, Germany., Pirastu M; Institute of Genetic and Biomedical Research, National Research Council of Italy, UOS of Sassari, Sassari, Italy., Pirastu N; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Pistis G; Department of Psychiatry, University Hospital of Lausanne, Lausanne, Switzerland., Polasek O; Faculty of Medicine, University of Split, Split, Croatia.; Gen-info Ltd, Zagreb, Croatia., Ponte B; Nephrology Service, Department of Specialties in Internal Medicine, University Hospitals of Geneva, Geneva, Switzerland., Porteous DJ; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Poulain T; LIFE Research Centre for Civilization Diseases, University of Leipzig, Leipzig, Germany., Preuss MH; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Rabelink TJ; Section of Nephrology, Department of Internal Medicine, Leiden University Medical Centre, Leiden, the Netherlands.; Einthoven Laboratory of Experimental Vascular Research, Leiden University Medical Centre, Leiden, the Netherlands., Raffield LM; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland., Rettig R; Institute of Physiology, University Medicine Greifswald, Karlsburg, Germany., Rheinberger M; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Rice KM; Department of Biostatistics, University of Washington, Seattle, WA, USA., Rizzi F; Department of Health Sciences, University of Milan, Milano, Italy.; ePhood Scientific Unit, ePhood SRL, Milano, Italy., Robino A; Institute for Maternal and Child Health-IRCCS Burlo Garofolo, Trieste, Italy., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Krajcoviechova A; Center for Cardiovascular Prevention, First Faculty of Medicine, Charles University and Thomayer Hospital, Prague, Czech Republic.; Thomayer Hospital, Prague, Czech Republic., Cifkova R; Center for Cardiovascular Prevention, First Faculty of Medicine, Charles University and Thomayer Hospital, Prague, Czech Republic.; Department of Medicine II, First Faculty of Medicine, Charles University, Prague, Czech Republic., Rueedi R; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Ruggiero D; Institute of Genetics and Biophysics Adriano Buzzati-Traverso-CNR, Naples, Italy.; IRCCS Neuromed, Pozzilli, Italy., Ryan KA; Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA., Saba Y; Molecular Biology and Biochemistry, Gottfried Schatz Research Centre for Cell Signaling, Metabolism and Aging, Medical University of Graz, Graz, Austria., Salvi E; Department of Health Sciences, University of Milan, Milano, Italy.; Neurology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Schmidt H; Institute of Molecular Biology and Biochemistry, Centre for Molecular Medicine, Medical University of Graz, Graz, Austria., Schmidt R; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria., Shaffer CM; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA., Smith AV; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland., Smith BH; Division of Population Health and Genomics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Spracklen CN; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Centre for Environmental Health, Neuherberg, Germany.; Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU Munich, Munich, Germany., Stumvoll M; Division of Endocrinology, Nephrology and Rheumatology, University of Leipzig, Leipzig, Germany., Sulem P; deCODE Genetics, Amgen Inc., Reykjavik, Iceland., Tajuddin SM; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, National Institutes of Health, Baltimore, MD, USA., Teren A; LIFE Research Centre for Civilization Diseases, University of Leipzig, Leipzig, Germany.; Heart Centre Leipzig, Leipzig, Germany., Thiery J; LIFE Research Centre for Civilization Diseases, University of Leipzig, Leipzig, Germany.; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University of Leipzig, Leipzig, Germany., Thio CHL; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Thorsteinsdottir U; deCODE Genetics, Amgen Inc., Reykjavik, Iceland., Toniolo D; San Raffaele Research Institute, Milano, Italy., Tönjes A; Department of Endocrinology and Nephrology, University of Leipzig, Leipzig, Germany., Tremblay J; Montreal University Hospital Research Centre, Centre Hospitalier de lUniversité de Montréal, Montreal, Quebec, Canada.; Centre de Recherche du CHUM, Montreal, Quebec, Canada., Uitterlinden AG; Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Vaccargiu S; Institute of Genetic and Biomedical Research, National Research Council of Italy, UOS of Sassari, Sassari, Italy., van der Harst P; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Durrer Centre for Cardiovascular Research, the Netherlands Heart Institute, Utrecht, the Netherlands., van Duijn CM; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands., Verweij N; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Genomics plc, Oxford, UK., Völker U; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany.; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Vollenweider P; Internal Medicine, Department of Medicine, Lausanne University Hospital, Lausanne, Switzerland., Waeber G; Internal Medicine, Department of Medicine, Lausanne University Hospital, Lausanne, Switzerland., Waldenberger M; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Centre for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München-German Research Centre for Environmental Health, Neuherberg, Germany.; German Centre for Cardiovascular Research, Partner Site Munich Heart Alliance, Munich, Germany., Whitfield JB; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Wild SH; Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Wilson JF; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Yang Q; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Zhang W; Department of Epidemiology and Biostatistics, Faculty of Medicine, School of Public Health, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, London, UK., Zonderman AB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, National Institutes of Health, Baltimore, MD, USA., Bochud M; Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland., Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Centre, Jackson, MS, USA., Pendergrass SA; Geisinger Research, Biomedical and Translational Informatics Institute, Danville, PA, USA., Ho K; Kidney Health Research Institute, Geisinger, Danville, PA, USA.; Department of Nephrology, Geisinger, Danville, PA, USA., Parsa A; Division of Kidney, Urologic and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Pramstaller PP; Eurac Research, Institute for Biomedicine, Bolzano, Italy., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, Department of Epidemiology, Department of Health Service, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA., Böger CA; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.; Department of Nephrology and Rheumatology, Kliniken Südostbayern AG, Traunstein, Germany., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Butterworth AS; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Okada Y; Laboratory for Statistical Analysis, RIKEN Centre for Integrative Medical Sciences, Osaka, Japan.; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Osaka, Japan., Edwards TL; Division of Epidemiology, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University Medical Centre, Nashville, TN, USA.; Department of Veterans Affairs, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Stefansson K; deCODE Genetics, Amgen Inc., Reykjavik, Iceland., Susztak K; Department of Medicine and Genetics, University of Pennsylvania, Philadelphia, PA, USA., Scholz M; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE Research Centre for Civilization Diseases, University of Leipzig, Leipzig, Germany., Heid IM; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Hung AM; Vanderbilt University Medical Centre, Division of Nephrology & Hypertension, Nashville, TN, USA.; Department of Veterans Affairs, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany., Pattaro C; Eurac Research, Institute for Biomedicine, Bolzano, Italy., Woodward OM; Department of Physiology, University of Maryland School of Medicine, Baltimore, MD, USA., Vitart V; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Köttgen A; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. anna.koettgen@uniklinik-freiburg.de.; Institute of Genetic Epidemiology, Department of Biometry, Epidemiology and Medical Bioinformatics, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany. anna.koettgen@uniklinik-freiburg.de.

Publikováno v: Nature genetics [Nat Genet] 2019 Oct; Vol. 51 (10), pp. 1459-1474. Date of Electronic Publication: 2019 Oct 02.

Novel differences in renal gene expression in a diet-induced obesity model.

Autor: Halperin Kuhns VL; Department of Physiology, Johns Hopkins University School of Medicine , Baltimore, Maryland., Pluznick JL; Department of Physiology, Johns Hopkins University School of Medicine , Baltimore, Maryland.

Publikováno v: American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2018 Apr 01; Vol. 314 (4), pp. F517-F530. Date of Electronic Publication: 2017 Nov 15.