S1PR1 inhibition induces proapoptotic signaling in T cells and limits humoral responses within lymph nodes.

Autor: Dixit D; Departments of Cell Biology and Pathology, New York University Grossman School of Medicine, New York, New York, USA., Hallisey VM; Departments of Cell Biology and Pathology, New York University Grossman School of Medicine, New York, New York, USA., Zhu EY; Departments of Cell Biology and Pathology, New York University Grossman School of Medicine, New York, New York, USA., Okuniewska M; Departments of Cell Biology and Pathology, New York University Grossman School of Medicine, New York, New York, USA., Cadwell K; Department of Medicine and Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Chipuk JE; Department of Oncological Sciences, Department of Dermatology, and Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Axelrad JE; Division of Gastroenterology, Department of Medicine, New York University Grossman School of Medicine, New York, New York, USA., Schwab SR; Departments of Cell Biology and Pathology, New York University Grossman School of Medicine, New York, New York, USA.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2024 Jan 09; Vol. 134 (4). Date of Electronic Publication: 2024 Jan 09.

Sphingosine 1-phosphate receptor 1 inhibition induces a pro-apoptotic signaling cascade in T cells.

Autor: Dixit D, Hallisey VM, Zhu EYS, Okuniewska M, Cadwell K, Chipuk JE, Axelrad JE, Schwab SR

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Aug 22. Date of Electronic Publication: 2023 Aug 22.

Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression.

Autor: Fishbein A; Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215., Wang W; Department of Entomology and Nematology, University of California, Davis, CA 95616.; University of California, Davis Comprehensive Cancer Center, University of California, Davis, CA 95616., Yang H; Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215., Yang J; Department of Entomology and Nematology, University of California, Davis, CA 95616.; University of California, Davis Comprehensive Cancer Center, University of California, Davis, CA 95616., Hallisey VM; Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215., Deng J; Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215., Verheul SML; Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215., Hwang SH; Department of Entomology and Nematology, University of California, Davis, CA 95616.; University of California, Davis Comprehensive Cancer Center, University of California, Davis, CA 95616., Gartung A; Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215., Wang Y; Department of Entomology and Nematology, University of California, Davis, CA 95616.; University of California, Davis Comprehensive Cancer Center, University of California, Davis, CA 95616., Bielenberg DR; Vascular Biology Program, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115., Huang S; Institute for Systems Biology, Seattle, WA 98109., Kieran MW; Division of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215.; Department of Pediatric Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115., Hammock BD; Department of Entomology and Nematology, University of California, Davis, CA 95616; bdhammock@ucdavis.edu dpanigra@bidmc.harvard.edu.; University of California, Davis Comprehensive Cancer Center, University of California, Davis, CA 95616., Panigrahy D; Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215; bdhammock@ucdavis.edu dpanigra@bidmc.harvard.edu.; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Sep 01; Vol. 117 (35), pp. 21576-21587. Date of Electronic Publication: 2020 Aug 14.

Lipid mediators in the regulation of innate and adaptive immunity.

Autor: Torres, Raul M.¹ (AUTHOR) raul.torres@cuanschutz.edu, Cyster, Jason² (AUTHOR)

Publikováno v: Immunological Reviews. Aug2023, Vol. 317 Issue 1, p4-7. 4p.

Insights into phenotypic and functional CD8⁺ TRM heterogeneity.

Autor: Heeg, Maximilian¹ (AUTHOR), Goldrath, Ananda W.¹ (AUTHOR) agoldrath@ucsd.edu

Publikováno v: Immunological Reviews. Jul2023, Vol. 316 Issue 1, p8-22. 15p.