Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Hallie S. Wald"'
Autor:
Tito Borner, Hallie S. Wald, Misgana Y. Ghidewon, Bei Zhang, Zhidan Wu, Bart C. De Jonghe, Danna Breen, Harvey J. Grill
Publikováno v:
Cell Reports, Vol 31, Iss 3, Pp - (2020)
Summary: The anorectic and weight-suppressive effects of growth differentiation factor-15 (GDF15) are attracting considerable attention for treating obesity. Current experiments in rats investigate whether GDF15 induces an aversive visceral malaise-b
Externí odkaz:
https://doaj.org/article/771280ea69e14f68a0c7997a5e3f4500
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 324:R547-R555
Hindbrain growth hormone secretagogue receptor (GHSR) agonism increases food intake, yet the underlying neural mechanisms remain unclear. The functional effects of hindbrain GHSR antagonism by its endogenous antagonist liver-expressed antimicrobial p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f25b14af612c13d3bbf2e779af0381e3
https://doi.org/10.1152/ajpregu.00232.2022
https://doi.org/10.1152/ajpregu.00232.2022
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
Oxytocin (OT) is a neuropeptide whose central receptor-mediated actions include reducing food intake. One mechanism of its behavioral action is the amplification of the feeding inhibitory effects of gastrointestinal (GI) satiation signals processed b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd59737c7b3286dc8ccc954344cd2c2d
https://pubmed.ncbi.nlm.nih.gov/33026822
https://pubmed.ncbi.nlm.nih.gov/33026822
Autor:
Hallie S. Wald, Misgana Y. Ghidewon, Tito Borner, Bei Zhang, Harvey J. Grill, Bart C. De Jonghe, Zhidan Wu, Danna M. Breen
Publikováno v:
Cell Reports, Vol 31, Iss 3, Pp-(2020)
Cell Rep
Cell Rep
Summary: The anorectic and weight-suppressive effects of growth differentiation factor-15 (GDF15) are attracting considerable attention for treating obesity. Current experiments in rats investigate whether GDF15 induces an aversive visceral malaise-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::835e6296973fd53e3aa3d891a6087dcb
http://www.sciencedirect.com/science/article/pii/S2211124720304435
http://www.sciencedirect.com/science/article/pii/S2211124720304435
Autor:
Zhi Yi Ong, Harvey J. Grill, Amber L. Alhadeff, Sineadh M. Conway, Mitchell F. Roitman, Hallie S. Wald
Publikováno v:
Brain Res
Hunger resulting from food deprivation is associated with negative affect. This is supported by recent evidence showing that hunger-sensitive neurons drive feeding through a negative valence teaching signal. However, the complementary hypothesis that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4dd5b895e5bf14ee77cbb957bc8c0ed
https://pubmed.ncbi.nlm.nih.gov/31513793
https://pubmed.ncbi.nlm.nih.gov/31513793
Autor:
Harvey J. Grill, Hallie S. Wald
Publikováno v:
Obesity (Silver Spring, Md.)
OBJECTIVE This study investigated whether individual differences in behavioral responses to palatable food and to the satiation signal cholecystokinin (CCK) in outbred chow-maintained Sprague-Dawley rats enabled prediction of individual differences i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d82debe59369c79c5326c0480936b5a6
https://pubmed.ncbi.nlm.nih.gov/30998842
https://pubmed.ncbi.nlm.nih.gov/30998842
Autor:
Anna Kamitakahara, Scott E. Kanoski, Myrtha Arnold, Hallie S. Wald, Elizabeth A. Davis, Andrea N. Suarez, Jaimie W. Polson, Guillaume de Lartigue, Jasenka Zubcevic, Clarissa M. Liu, Alyssa M. Cortella, Harvey J. Grill
Publikováno v:
Curr Biol
Vagal afferent neuron (VAN) signaling sends information from the gut to the brain and is fundamental in the control of feeding behavior and metabolism [1]. Recent findings reveal that VAN signaling also plays a critical role in cognitive processes, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3101d1f80293eeedf8ee15f66f1cb348
https://doi.org/10.1016/j.cub.2020.08.069
https://doi.org/10.1016/j.cub.2020.08.069
Autor:
Nahor Haddish-Berhane, Sylvia Musto, Frank Barletta, Judy Lucas, Tracey Clark, Frank Loganzo, Steven Hansel, Dhaval K. Shah, Alison Betts, Hallie S. Wald
Publikováno v:
Journal of pharmacokinetics and pharmacodynamics. 45(2)
The objective of this manuscript was to establish in vitro–in vivo correlation (IVIVC) between the in vitro efficacy and in vivo efficacy of antibody drug conjugates (ADCs), using a PK/PD modeling approach. Nineteen different ADCs were used to deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc81152264b9a2f8c46699718915e82
https://pubmed.ncbi.nlm.nih.gov/29423862
https://pubmed.ncbi.nlm.nih.gov/29423862
Autor:
Kevin P. Myers, Hallie S. Wald
Publikováno v:
Physiologybehavior. 151
Through flavor–nutrient conditioning rats learn to prefer and increase their intake of flavors paired with rewarding, postingestive nutritional consequences. Since obesity is linked to altered experience of food reward and to perturbations of nutri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8c42c4b2da542294bf7099b6b5eca3b
https://pubmed.ncbi.nlm.nih.gov/26150317
https://pubmed.ncbi.nlm.nih.gov/26150317
Autor:
Jeremy S. Myers, Sylvia Musto, Hallie S. Wald, Frank Loganzo, Manoj Charati, Judy Lucas, Hans-Peter Gerber, Fang Wang, Russell Dushin, Bryan Peano, Xingzhi Tan, Megan Wojciechowicz, Andreas Maderna, My-Hanh Lam
Publikováno v:
Cancer Research. 74:4837-4837
Antibody drug conjugates (ADCs) are designed to deliver cytotoxics to tumor cells via binding to surface antigen followed by internalization and intracellular drug release. ADC linkers are typically categorized as non-cleavable or cleavable; a cleava
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::229ca6ad7ae28f086d4ba6cd6eede109
https://doi.org/10.1158/1538-7445.am2014-4837
https://doi.org/10.1158/1538-7445.am2014-4837