Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Halley Shukla"'
Autor:
John P. Dowling, Pavel A. Nikitin, Fang Shen, Halley Shukla, James P. Finn, Nirja Patel, Cezary Swider, Jamie L. Bingaman-Steele, Chris Nicolescu, Eden L Sikorski, Evan J. Greenawalt, Michael J. Morin, Matthew K. Robinson, Karen Lundgren, Benjamin C. Harman
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTImmune checkpoint inhibitors that overcome T cell suppressive mechanisms in tumors have revolutionized the treatment of cancer but are only efficacious in a small subset of patients. Targeting suppressive mechanisms acting on innate immune ce
Externí odkaz:
https://doaj.org/article/687ffc074dce4fcdb4a25e4af9665e76
Autor:
John Dowling, Pavel Nikitin, Cezary Swider, Chris Nicolescu, Halley Shukla, Jamie Bingaman-Steele, Nirja Patel, Eden Sikorski, Benjamin Harman, Jillian DiMuzio, Karen Lundgren, Yumi Ohtani, Michael Morin, Matthew Robinson, Fang Shen
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fea737a0bf0bd9419649e65c36ecccf
https://doi.org/10.1136/jitc-2022-sitc2022.0823
https://doi.org/10.1136/jitc-2022-sitc2022.0823
Autor:
Pavel A. Nikitin, Jillian M. DiMuzio, John P. Dowling, Nirja B. Patel, Jamie L. Bingaman-Steele, Baron C. Heimbach, Noeleya Henriquez, Chris Nicolescu, Antonio Polley, Eden L. Sikorski, Raymond J. Howanski, Mitchell Nath, Halley Shukla, Suzanne M. Scheaffer, James P. Finn, Li-Fang Liang, Todd Smith, Nadia Storm, Lindsay G. A. McKay, Rebecca I. Johnson, Lauren E. Malsick, Anna N. Honko, Anthony Griffiths, Michael S. Diamond, Purnanand Sarma, Dennis H. Geising, Michael J. Morin, Matthew K. Robinson
Publikováno v:
Science Immunology. 7
Monoclonal antibodies are an efficacious therapy against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, rapid viral mutagenesis led to escape from most of these therapies, outlining the need for an antibody cocktail with a bro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba9c0fe6a471aff9ca68ce2d284df07
https://doi.org/10.1126/sciimmunol.abl9943
https://doi.org/10.1126/sciimmunol.abl9943
Autor:
Zhenquan Jia, Hong Zhu, Xiaolun Sun, Y. Robert Li, Ho Young Lee, Gabriella Gaje, Ashkon Koucheki, Halley Shukla, Humaira A. Bibi
Publikováno v:
Molecular and Cellular Biochemistry. 474:27-39
Epidemiological studies have exhibited a strong correlation between exposure to air pollution and deaths due to vascular diseases such as atherosclerosis. Benzo-a-pyrene-1,6-quinone (BP-1,6-Q) is one of the components of air pollution. This study was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eceec8cece9a706712621d58fcc3c549
https://doi.org/10.1007/s11010-020-03831-6
https://doi.org/10.1007/s11010-020-03831-6
Autor:
Zhenquan Jia, Gabriella Gaje, Michael A. Trush, Rojin Chitrakar, Halley Shukla, Humaira A. Bibi, Y. Robert Li, Hong Zhu, Ashkon Koucheki
Publikováno v:
Toxicology Letters. 322:120-130
Strong epidemiological evidence supports the association between increased air pollution and the risk of developing atherosclerotic cardiovascular diseases (CVDs). However, the mechanism remains unclear. As an environmental air pollutant and benzo-a-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39b9dd86222244229d5b06df5e8e6fbd
https://doi.org/10.1016/j.toxlet.2020.01.011
https://doi.org/10.1016/j.toxlet.2020.01.011
Autor:
Pavel A. Nikitin, Jillian M. DiMuzio, John P. Dowling, Nirja B. Patel, Jamie L. Bingaman-Steele, Baron C. Heimbach, Noeleya Henriquez, Chris Nicolescu, Antonio Polley, Eden L. Sikorski, Raymond J. Howanski, Mitchell Nath, Halley Shukla, Suzanne M. Scheaffer, James P. Finn, Li-Fang Liang, Todd Smith, Nadia Storm, Lindsay G. A. McKay, Rebecca I. Johnson, Lauren E. Malsick, Anna N. Honko, Anthony Griffiths, Michael S. Diamond, Purnanand Sarma, Dennis H. Geising, Michael J. Morin, Matthew K. Robinson
Using an unbiased interrogation of the anti-viral memory B cell repertoire of convalescent COVID-19 patients, we identified three human antibodies that when combined demonstrated both robust viral suppressive properties against all tested SARS-CoV-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fca46853486ce71107671127e851ce01
https://doi.org/10.1101/2021.10.18.464900
https://doi.org/10.1101/2021.10.18.464900
Autor:
John P Dowling, Pavel A Nikitin, Fang Shen, James P Finn, Nirja Patel, Cezary Swider, Jamie Steele, Halley Shukla, Matthew K Robinson, Karen Lundgren, Benjamin C Harman
Publikováno v:
Molecular Cancer Therapeutics. 20:LBA022-LBA022
Immune checkpoint inhibitors that overcome T cell suppressive mechanisms in tumors have revolutionized the treatment of cancer. However, therapies targeting innate immune cell subsets that orchestrate adaptive immune responses could significantly imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50521b0d8fffba8fe695268fd3568269
https://doi.org/10.1158/1535-7163.targ-21-lba022
https://doi.org/10.1158/1535-7163.targ-21-lba022
Autor:
Halley Shukla, Zhenquan Jia, Y. Robert Li, Ho Young Lee, Michael A. Trush, Xiaolun Sun, Hong Zhu, Gabriella Gaje, Ashkon Koucheki
Publikováno v:
Toxicology and applied pharmacology. 404
Numerous studies conducted in the past have reported deaths in the human population due to cardiovascular diseases (CVD) on exposure to air particulate matter (APM). BP-1,6-quinone (BP-1,6-Q) is one of the significant components of APM. However, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a0e0d7d29821e2e1610d3fae0c085f0
https://pubmed.ncbi.nlm.nih.gov/32739527
https://pubmed.ncbi.nlm.nih.gov/32739527