Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Hall IA"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Hall Ian P
Publikováno v:
Respiratory Research, Vol 1, Iss 1, Pp 6-8 (2000)
Abstract The interleukin-4 (IL-4) signalling cascade has been identified as a pathway potentially important in the development of asthma. Genetic variants within this signalling pathway might contribute to the risk of developing asthma in a given ind
Externí odkaz:
https://doaj.org/article/d22372c8f2024709bf4ceadd36bf9888
Autor:
Hall Ian P, Billington Charlotte K
Publikováno v:
Respiratory Research, Vol 12, Iss 1, p 89 (2011)
Abstract Background β2-adrenoceptor agonists elicit bronchodilator responses by binding to β2-adrenoceptors on airway smooth muscle (ASM). In vivo, the time between drug administration and clinically relevant bronchodilation varies significantly de
Externí odkaz:
https://doaj.org/article/9035eb00ecff4072b5a4c3d9a58c5db2
Publikováno v:
Respiratory Research, Vol 11, Iss 1, p 168 (2010)
Abstract Background Agonist stimulation of airway smooth muscle (ASM) results in IP3 mediated Ca2+ release from the sarcoplasmic reticulum followed by the activation of store operated and receptor operated non-selective cation channels. Activation of
Externí odkaz:
https://doaj.org/article/172270ca477044a3aec3a29da2d97126
Publikováno v:
BMC Infectious Diseases, Vol 10, Iss 1, p 25 (2010)
Abstract Background In the event of a release of a pathogen such as smallpox, which is human-to-human transmissible and has high associated mortality, a key question is how best to deploy containment and control strategies. Given the general uncertai
Externí odkaz:
https://doaj.org/article/d4d645abcfae4a3c981cfb60d89df7ad
Autor:
Connolly Martin J, Wardlaw Andrew J, Moffat Miriam F, Parker Stuart G, Hall Ian P, Stewart Ceri E, Ruse Charlotte, Sayers Ian
Publikováno v:
BMC Medical Genetics, Vol 10, Iss 1, p 112 (2009)
Abstract Background We have previously identified Urokinase Plasminogen Activator Receptor (PLAUR) as an asthma susceptibility gene. In the current study we tested the hypothesis that PLAUR single nucleotide polymorphisms (SNPs) determine baseline lu
Externí odkaz:
https://doaj.org/article/7853011ff0d64f3ea6506d0c25bcc527
Autor:
Ferreira Manuel A, Wjst Matthias, Blakey John, Koppelman Gerard H, Denham Samuel, Hall Ian P, Sayers Ian
Publikováno v:
Respiratory Research, Vol 9, Iss 1, p 38 (2008)
Abstract Background Asthma and allergy are complex multifactorial disorders, with both genetic and environmental components determining disease expression. The use of molecular genetics holds great promise for the identification of novel drug targets
Externí odkaz:
https://doaj.org/article/51ffd056fe914dbf9084ec15a33d7d12
Autor:
Swan Caroline, Peel Samantha, Stewart Ceri, Duroudier Nathalie, Browning Claudia A, Smith Natalie, Hall Ian P, Sayers Ian
Publikováno v:
Respiratory Research, Vol 8, Iss 1, p 68 (2007)
Abstract Background Airway hyper-responsiveness (AHR) is a key feature of asthma and a causal relationship between airway inflammation and AHR has been identified. The aim of the current study was to clarify the effect of proinflammatory cytokines an
Externí odkaz:
https://doaj.org/article/947651eb636044a4b5afa78db444cf79
Publikováno v:
Respiratory Research, Vol 7, Iss 1, p 119 (2006)
Abstract Background Control of cytosolic calcium plays a key role in airway myocyte function. Changes in intracellular Ca2+ stores can modulate contractile responses, modulate proliferation and regulate synthetic activity. Influx of Ca2+ in non excit
Externí odkaz:
https://doaj.org/article/15bb3bd59c724a5eb0705246d3eed056