Výsledky vyhledávání - "Hall, Wiley R."

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Dantrolene for the Prevention and Treatment of Cerebral Vasospasm after Subarachnoid Hemorrhage – a Randomized Placebo-Controlled Trial to assess Safety, Tolerability and Feasibility

Autor: Muehlschlegel, Susanne, Carandang, Raphael A., Hall, Wiley R., Kini, Nisha, Izzy, Saef, VanDerBom, I. Martijn, Flood, Thomas F., Gounis, Matthew J., Weaver, John P., Barton, Bruce A.

Introduction: Dantrolene is neuroprotective in animal models and may attenuate cerebral vasospasm (cVSP) after aneurysmal subarachnoid hemorrhage (aSAH) in humans. We evaluated safety/tolerability and feasibility of intravenous dantrolene (IV-D) afte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::906bce7822b236b022caa76d25bf7810

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Severity of Pre-existing Cerebral Small Vessel Disease is Associated with Outcome after Traumatic Brain Injury

Autor: Heninger, Nils, Izzy, Saef, Carandang, Raphael A., Hall, Wiley R., Muehlschlegel, Susanne

Background and purpose: It is now well accepted that traumatic white matter injury constitutes a critical determinant of post-traumatic functional impairment. However, the contribution of pre-existing white matter rarefaction on outcome following tra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ca407576c9771b2a8fa34fdaa87bc1b4

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BRAIN TOPiC Study: Assessing Variability in Traumatic Brain Injury (TBI) Outcome Prognostication – Do Self-Fulfilling Prophecies Exist in TBI, Too?

Autor: Izzy, Saef, Compton, Rebecca, Carandang, Raphael A., Hall, Wiley R., Muehlschlegel, Susanne

OBJECTIVE: In this study, we surveyed clinicians caring for patients with moderate-severe traumatic brain injury (msTBI) to assess (1) possible variability in outcome prognostication in TBI, varying by clinicians level of training and medical special

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e066247de78be0c2c30d80f17fdc3e88

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Genetic determinants of cerebral edema in severe traumatic brain injury: A pilot study of the role of CACNA1 and AQP4 gene mutations

Autor: Carandang, Raphael A., Muehlschlegel, Susanne, Hall, Wiley R., Ouillette, Cynthia, Brown Jr., Robert H.

Cerebral edema is the one of the most significant predictors of poor outcome after traumatic brain injury. It is still unclear what the pathophysiological and cellular mechanisms and predictors of post-traumatic edema are. The exponential growth in g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2074d1badbe3ce3792f28e5614038097

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Impact of medical and neurological ICU complications on moderate-severe traumatic brain injury (TBI)

Autor: Muehlschlegel, Susanne, Carandang, Raphael A., Ouillette, Cynthia, Hall, Wiley R., Anderson Jr., Frederick A., Goldberg, Robert J.

Certain admission characteristics are known predictors of adverse outcomes in patients with moderate-severe TBI, but explain only 1/3 of outcome variability. Intensive care unit (ICU) complications occur frequently in this population, but their impac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4ffdf1dbd9ac6ef701dd241cf7e7bc27

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Incidence rates of ICU complications in moderate-severe traumatic brain injury (TBI)

Autor: Muehlschlegel, Susanne, Carandang, Raphael A., Ouillette, Cynthia, Hall, Wiley R., Anderson Jr., Frederick A., Goldberg, Robert J.

Retrospective studies suggest that non-neurologic organ failure may contribute to 2/3 of all deaths after TBI, but the actual incidence rates of specific intensive care unit (ICU) complications in moderate-severe TBI are not known. In a prospective o

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Serum sodium values and their association with adverse outcomes in moderate-severe traumatic brain injury (TBI)

Autor: Rivera Lara, Lucia, Muehlschlegel, Susanne, Carandang, Raphael A., Ouillette, Cynthia, Hall, Wiley R., Anderson Jr., Frederick A., Goldberg, Robert J.

Hypernatremia in neurocritically ill patients has been associated with worse neurological outcomes. There may, however, be a treatment effect from osmotherapy combating herniation and hyponatremia, which in turn may exacerbate brain edema, resulting

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::612eccd17392f08009723d0045c367d3

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