Could dysregulation of RASSF1 expression be a mechanism of tumorigenesis in CTVT?

Autor: Haline B. Fêo, Luis Mauricio M. Flórez, Ricardo S. Yamatogi, Anderson P. Duzanski, João P. Araújo Junior, Rogerio A. Oliveira, Noeme S. Rocha

Publikováno v: Pesquisa Veterinária Brasileira v.42 2022
Pesquisa Veterinária Brasileira
Colégio Brasileiro de Patologia Animal (CBPA)
instacron:EMBRAPA

Canine transmissible venereal tumor (CTVT) is the oldest known somatic cell lineage. It is a transmissible cancer that propagates naturally in dogs and reportedly contains gene mutations. RASSF1 participates in DNA damage repair, and its downregulati

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