Zobrazeno 1 - 4
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pro vyhledávání: '"Halina Nocon"'
Autor:
Halina Nocon, M Melzacka
Publikováno v:
Journal of Pharmacy and Pharmacology. 43:564-568
An ex-vivo and in-vitro study of the effects of imipramine on the membrane anisotropy and phospholipid methylation in the rat cortical membranes was carried out. A comparative study of the membrane fluidity in various brain regions indicated differen
Publikováno v:
Biochemical pharmacology. 46(3)
This study investigates the effect of imipramine (IMI) on the methylation of phosphatidylethanolamine (PE) in crude cortical membranes of rat brain in vitro and ex vivo. It was found that IMI enhanced the formation of phosphatidyl-N-monomethylethanol
Publikováno v:
The Journal of pharmacy and pharmacology. 43(1)
Regional distribution of imipramine, desipramine and specific [3H]desipramine binding sites in the rat brain after acute and chronic treatment of rats with imipramine has been investigated. Both substances were distributed unevenly within rat brain a
Publikováno v:
The Journal of pharmacy and pharmacology. 42(9)
Ipsapirone, a putative non-benzodiazepine anxiolytic, was extensively metabolized in rats to 1-(2-pyrimidinyl)piperazine (1-PP) which accumulated in the brain. Neither the route of administration (i.p. or p.o.), nor prolonged administration of ipsapi