Výsledky vyhledávání - "Halina Kusnierczyk"

Further development of local IL-2 therapy of cancer: multiple versus single IL-2 treatment of transplanted murine colon carcinoma

Autor: Willem Den Otter, Halina Kusnierczyk, Krzysztof Krawczyk, Caspaar Bijleveld, Elżbieta Pajtasz-Piasecka, J. W. Koten

Publikováno v: Cancer Immunology, Immunotherapy. 53:445-452

We have compared the effect of one and up to four local IL-2 treatments of transplanted MC38 colon carcinoma. A single IL-2 treatment prolonged the survival time ( p=0.015), but no cure was obtained. One local IL-2 treatment inhibited tumor growth fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d648ee67ef7552bf9c34d66e35049853
https://doi.org/10.1007/s00262-003-0490-8

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Synergistic antitumour effects of chemo-immunotherapy with an oxazaphosphorine drug and IL-2-secreting cells in a mouse colon cancer model

Autor: C Radzikowski, Elżbieta Pajtasz-Piasecka, Halina Kusnierczyk

Publikováno v: Medical Oncology. 16:267-278

The therapeutic efficacies of two chemical agents-cyclophosphamide (CY) and compound CBM-11-were compared in a chemo-immunotherapy protocol combining a single injection of a cytotoxic agent with a series of weekly peritumoural (p.t.) administrations

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0703223db46c06596d78159781476271
https://doi.org/10.1007/bf02785873

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Synthesis and antitumour activity of stereoisomers of 4-hydroperoxy derivatives of ifosfamide and its bromo analogue

Autor: Adam Opolski, Halina Kusnierczyk, Konrad Misiura, Daria Szymanowicz, Joanna Wietrzyk

Publikováno v: Farmaco (Societa chimica italiana : 1989). 57(4)

Racemic mixtures and laevorotatory enantiomers of cis- and trans-4-hydroperoxyifosfamide and 4-hydroperoxybromofosfamide possess high antitumour activity both in vitro and in vivo. However, no major differences in biological activity were observed am

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c73938f3620acd0cd7aac282ed197ea
https://pubmed.ncbi.nlm.nih.gov/11989810

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Synthesis, in vitro metabolic studies, and antitumour activity of methyl analogues of ifosfamide

Autor: Konrad Misiura, Halina Kusnierczyk, Karina Kardacka

Publikováno v: Archiv der Pharmazie. 334(8-9)

Synthesis of 2-chloro-1,1-dimethylethyl and 2-chloro-2,2-dimethylethyl analogues of ifosfamide was performed via aziridine intermediate. In vitro metabolic activation showed that both compounds are metabolised at a rate similar to the parent drug. Ho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1edca2499a20803bc1684adedc190f97
https://pubmed.ncbi.nlm.nih.gov/11688140

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