Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Halina Dobrzyn"'
Autor:
Zeyuan Yin, Eleonora Torre, Manon Marrot, Colin H. Peters, Amy Feather, William G. Nichols, Sunil Jit R. J. Logantha, Areej Arshad, Simran Agnes Martis, Nilay Tugba Ozturk, Weixuan Chen, Jiaxuan Liu, Jingmo Qu, Min Zi, Elizabeth J. Cartwright, Catherine Proenza, Angelo Torrente, Matteo E. Mangoni, Halina Dobrzynski, Andrew J. Atkinson
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundThe sinoatrial node (SN) generates the heart rate (HR). Its spontaneous activity is regulated by a complex interplay between the modulation by the autonomic nervous system (ANS) and intrinsic factors including ion channels in SN cells. Howe
Externí odkaz:
https://doaj.org/article/c4c21de8b7b44bc582fd73e768507905
Autor:
Weixuan Chen, Jingmo Qu, Daniel Rams, Maciej Zajac, Raghad Albalawi, Abimbola Aminu, Malgorzata Mazur, Mateusz K. Holda, Jerzy Walocha, Krzysztof Gil, Marcin Kuniewicz, Halina Dobrzynski, Andrew Atkinson
Publikováno v:
Translational Research in Anatomy, Vol 37, Iss , Pp 100351- (2024)
Research purpose: The sinoatrial node (SN) is the main pacemaker site, and it is located in the junctional area of the superior vena cava within the right atrium (RA). The precise micro-anatomy of the SN in males and females in ageing and obesity rem
Externí odkaz:
https://doaj.org/article/b1a0eeb5258d48b9b1f945a6bc6b226e
Publikováno v:
Translational Research in Anatomy, Vol 37, Iss , Pp 100330- (2024)
Background: The cardiac conduction system (CCS) initiates and propagates electrical impulses across the heart. Scientists of both sexes have played unprecedented roles in discovering the CCS and advancing our anatomical, electrophysiological, and mol
Externí odkaz:
https://doaj.org/article/bb3b8975802b43bfb3a68ce8d6da187d
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract The sinus node (SN) serves as the primary pacemaker of the heart and is the first component of the cardiac conduction system. Due to its anatomical properties and sample scarcity, the cellular composition of the human SN has been historicall
Externí odkaz:
https://doaj.org/article/ef26873119ee44129891b57221771124
Autor:
Danila Potyagaylo, Peter M. van Dam, Marcin Kuniewicz, Damian Dolega-Dolegowski, Agnieszka Pregowska, Andrew Atkinson, Halina Dobrzynski, Klaudia Proniewska
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
The most commonly applied way of teaching students to convey the foundations of human anatomy and physiology involves textbooks and lectures. This way of transmitting knowledge causes difficulties for students, especially in the context of three-dime
Externí odkaz:
https://doaj.org/article/147cb983c0044ec8895e0574980c0406
Autor:
Santiago Pined, David G. Allen, Dirk F. van Helden, Sreehari Kalvakuri, Halina Dobrzyn, Christiana Leimena, Renee Johnson, Andrew Atkinson, Richard P. Harvey, Diane Fatkin, Gunjan Trived, Ann-Kristin Altekoester, Karen Ocorr, Peter C. M. Molenaar, Arie Jacoby, Charles D. Cox, Dennis L. Kuchar, Rolf Bodmer, Monique Ohanian, Inken G. Huttner, Georg Vogler, Magdalena Soka, Vesna Nikolova-Krstevski, Yue-Kun Ju, Adam P. Hill
BackgroundKCNMA1 encodes the α-subunit of the large-conductance Ca2+-activated K+ channel, KCa1.1, and lies within a linkage interval for atrial fibrillation (AF). Insights into the cardiac functions of KCa1.1 are limited and KCNMA1 has not been inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47d38efcb107ad676586738e523b836b
https://doi.org/10.1101/2020.06.28.176495
https://doi.org/10.1101/2020.06.28.176495
Autor:
Weixuan Chen, Daniel Rams, Maciej Zając, Raghad Albalawi, Andrew J. Atkinson, Abimbola J. Aminu, Malgorzata Mazur, Mateusz K. Hołda, Jerzy Walocha, Krzysztof Gil, Marcin Kuniewicz, Halina Dobrzynski
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
IntroductionThe sinus node (SN) is the main pacemaker site of the heart, located in the upper right atrium at the junction of the superior vena cava and right atrium. The precise morphology of the SN in the human heart remains relatively unclear espe
Externí odkaz:
https://doaj.org/article/0fdd029f1516470292dd4af4196ee17e
Autor:
Claire Wilson, Min Zi, Matthew Smith, Munir Hussain, Alicia D’Souza, Halina Dobrzynski, Mark R. Boyett
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Heart failure is associated with atrioventricular (AV) node dysfunction, and AV node dysfunction in the setting of heart failure is associated with an increased risk of mortality and heart failure hospitalisation. This study aims to understand the ca
Externí odkaz:
https://doaj.org/article/a9cacd5076b54971b97dcd4a8af8d26b
Autor:
Ning Li, Esthela Artiga, Anuradha Kalyanasundaram, Brian J. Hansen, Amy Webb, Maciej Pietrzak, Brandon Biesiadecki, Bryan Whitson, Nahush A. Mokadam, Paul M. L. Janssen, John D. Hummel, Peter J. Mohler, Halina Dobrzynski, Vadim V. Fedorov
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Heart failure (HF) is frequently accompanied with the sinoatrial node (SAN) dysfunction, which causes tachy-brady arrhythmias and increased mortality. MicroRNA (miR) alterations are associated with HF progression. However, the transcriptome
Externí odkaz:
https://doaj.org/article/d1f3400a06c3430697951538c406b0ec
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract Physiological systems vary in a day-night manner anticipating increased demand at a particular time. Heart is no exception. Cardiac output is primarily determined by heart rate and unsurprisingly this varies in a day-night manner and is high
Externí odkaz:
https://doaj.org/article/c273968fb8c84a61a1ba8904335d6d83