Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Halima Osman"'
Publikováno v:
Cells, Vol 9, Iss 1, p 69 (2019)
Myocardial stress and injury invariably promote remodeling of the cardiac tissue, which is associated with cardiomyocyte death and development of fibrosis. The fibrotic process is initially triggered by the differentiation of resident cardiac fibrobl
Externí odkaz:
https://doaj.org/article/234539c3b075457aaea52664e83de1bd
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 5, Iss 1, p 12 (2018)
Heart failure is a lethal disease that can develop after myocardial infarction, hypertension, or anticancer therapy. In the damaged heart, loss of function is mainly due to cardiomyocyte death and associated cardiac remodeling and fibrosis. In this c
Externí odkaz:
https://doaj.org/article/2541d8024888435dbd72b2ea5696fb31
Publikováno v:
Biochemical Society Transactions
Cardiac stress initiates a pathological remodeling process that is associated with cardiomyocyte loss and fibrosis that ultimately leads to heart failure. In the injured heart, a pathologically elevated synthesis of reactive oxygen species (ROS) is t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::713ad4fb3839460d2b6c0602ca306be5
http://europepmc.org/articles/PMC6824835
http://europepmc.org/articles/PMC6824835
Publikováno v:
Cells
Cells, Vol 9, Iss 1, p 69 (2019)
Cells, Vol 9, Iss 1, p 69 (2019)
Myocardial stress and injury invariably promote remodeling of the cardiac tissue, which is associated with cardiomyocyte death and development of fibrosis. The fibrotic process is initially triggered by the differentiation of resident cardiac fibrobl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8ecac8eee024d6908052edae95ff813
http://europepmc.org/articles/PMC7016856
http://europepmc.org/articles/PMC7016856
Publikováno v:
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease, Vol 5, Iss 1, p 12 (2018)
Journal of Cardiovascular Development and Disease, Vol 5, Iss 1, p 12 (2018)
Heart failure is a lethal disease that can develop after myocardial infarction, hypertension, or anticancer therapy. In the damaged heart, loss of function is mainly due to cardiomyocyte death and associated cardiac remodeling and fibrosis. In this c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b337a701b9414af6e3419480b1ae021
https://pubmed.ncbi.nlm.nih.gov/29419761
https://pubmed.ncbi.nlm.nih.gov/29419761
Autor:
Cynthia Gonano, Erica Reggi, Francesco Raimondi, Michael Overduin, Francesca Fanelli, Clare L. Box, Elisa Dreyer, Dario Diviani, Halima Osman, Lucia Ruggieri, Michele Seeber, Sabrina Cavin, Luca Bellucci, Cosmo D. del Vescovo, Marc Lenoir
Publikováno v:
Cell chemical biology. 23(9)
Uncontrolled activation of Rho signaling by RhoGEFs, in particular AKAP13 (Lbc) and its close homologs, isimplicated in a number of human tumors with poor prognosis and resistance to therapy. Structure predictions and alanine scanning mutagenesis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::549ff5674a5e257302c0deabc6014a26
https://pubmed.ncbi.nlm.nih.gov/27593112
https://pubmed.ncbi.nlm.nih.gov/27593112