Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Halima Ouadid-Ahidouch"'
Autor:
Riadh Hmaidi, Ayoub Ksouri, Rahma Benabderrazek, Viviane Antonietti, Pascal Sonnet, Mathieu Gautier, Balkiss Bouhaouala-Zahar, Halima Ouadid-Ahidouch
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Scorpion α-toxins are neurotoxins that target the fast inactivation mechanism of voltage-gated sodium (NaV) channels leading to several neuro- and cardiotoxic effects in mammals. The toxin AahII is the most active α-toxin from the North African sco
Externí odkaz:
https://doaj.org/article/0d8f29728d1e4b4f934f5581a64d3ad3
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10687 (2022)
In the fight against cancer, therapeutic strategies using cisplatin are severely limited by the appearance of a resistant phenotype. While cisplatin is usually efficient at the beginning of the treatment, several patients endure resistance to this ag
Externí odkaz:
https://doaj.org/article/f2ad9d49e33e4bb183cbac6d7fb27d04
Autor:
Julie Auwercx, Philippe Kischel, Thibaut Lefebvre, Nicolas Jonckheere, Alison Vanlaeys, Stéphanie Guénin, Silviya Radoslavova, Isabelle Van Seuningen, Halima Ouadid-Ahidouch, Hemant M. Kocher, Isabelle Dhennin-Duthille, Mathieu Gautier
Publikováno v:
Cells, Vol 11, Iss 14, p 2255 (2022)
Pancreatic diseases, such as pancreatitis or pancreatic ductal adenocarcinoma, are characterized by the presence of activated pancreatic stellate cells (PSCs). These cells represent key actors in the tumor stroma, as they actively participate in dise
Externí odkaz:
https://doaj.org/article/6009ff74f34a461ebc08a18f17f2ec93
Autor:
Julie Schnipper, Sana Kouba, Frédéric Hague, Alban Girault, Pierre Rybarczyk, Marie-Sophie Telliez, Stéphanie Guénin, Riad Tebbakha, Henri Sevestre, Ahmed Ahidouch, Stine Falsig Pedersen, Halima Ouadid-Ahidouch
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7923 (2022)
Dysregulation of the transient receptor canonical ion channel (TRPC1) has been found in several cancer types, yet the underlying molecular mechanisms through which TRPC1 impacts pancreatic ductal adenocarcinoma (PDAC) cell proliferation are incomplet
Externí odkaz:
https://doaj.org/article/51597b621c1c4cb897885542fed1f27c
Autor:
Arthur Foulon, Pierre Rybarczyk, Nicolas Jonckheere, Eva Brabencova, Henri Sevestre, Halima Ouadid-Ahidouch, Lise Rodat-Despoix
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 2962 (2022)
Breast cancer is the leading cause of cancer death among women in worldwide and France. The disease prognosis and treatment differ from one breast cancer subtype to another, and the disease outcome depends on many prognostic factors. Deregulation of
Externí odkaz:
https://doaj.org/article/a806417c02154db295c66b1d1feb01c0
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Pancreatic ductal adenocarcinoma (PDAC) is the fourth most common cause of cancer-related deaths in United States and Europe. It is predicted that PDAC will become the second leading cause of cancer-related deaths during the next decades. The develop
Externí odkaz:
https://doaj.org/article/ca68948745884790ac7fcacfce2d289b
Autor:
Thibaut Lefebvre, Pierre Rybarczyk, Clara Bretaudeau, Alison Vanlaeys, Rémi Cousin, Sylvie Brassart-Pasco, Denis Chatelain, Isabelle Dhennin-Duthille, Halima Ouadid-Ahidouch, Bertrand Brassart, Mathieu Gautier
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Pancreatic ductal adenocarcinoma (PDAC) is a malignancy with a very poor prognosis due to highly metastatic profile. Cell migration is an essential step of the metastatic cascade allowing cancer cells to spread toward target tissues. Recent studies s
Externí odkaz:
https://doaj.org/article/46b57d45beb145bea9ff6802d48d3e05
Autor:
Alexis Caulier, Nicolas Jankovsky, Yohann Demont, Hakim Ouled-Haddou, Julien Demagny, Corinne Guitton, Lavinia Merlusca, Delphine Lebon, Pascal Vong, Aurélien Aubry, Agnès Lahary, Christian Rose, Sandrine Gréaume, Emilie Cardon, Jessica Platon, Halima Ouadid-Ahidouch, Jacques Rochette, Jean-Pierre Marolleau, Véronique Picard, Loïc Garçon
Publikováno v:
Haematologica, Vol 105, Iss 3 (2020)
Hereditary xerocytosis is a dominantly inherited red cell membrane disorder caused in most cases by gain-of-function mutations in PIEZO1, encoding a mechanosensitive ion channel that translates a mechanic stimulus into calcium influx. We found that P
Externí odkaz:
https://doaj.org/article/6806504b74624d9894dc56b0db43c8b2
Autor:
Mohamed Chamlali, Sana Kouba, Lise Rodat-Despoix, Luca Matteo Todesca, Zoltán Pethö, Albrecht Schwab, Halima Ouadid-Ahidouch
Publikováno v:
Cells, Vol 10, Iss 12, p 3487 (2021)
Orai3 calcium (Ca2+) channels are implicated in multiple breast cancer processes, such as proliferation and survival as well as resistance to chemotherapy. However, their involvement in the breast cancer cell migration processes remains vague. In the
Externí odkaz:
https://doaj.org/article/fec36aba3a24467da4ce2e62499c770d
Autor:
Pierre Rybarczyk, Alison Vanlaeys, Bertrand Brassart, Isabelle Dhennin-Duthille, Denis Chatelain, Henri Sevestre, Halima Ouadid-Ahidouch, Mathieu Gautier
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 4, Pp 288-300 (2017)
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a very poor prognosis. There is an urgent need to better understand the molecular mechanisms that regulate PDAC cell aggressiveness. The transient receptor potential melastatin
Externí odkaz:
https://doaj.org/article/27c8b66a754840ef89bd4cd1e6748b65