Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Halima, Amhaoul"'
Autor:
Daniele Bertoglio, Halima Amhaoul, Joery Goossens, Idrish Ali, Elisabeth Jonckers, Tom Bijnens, Matteo Siano, Leonie wyffels, Jeroen Verhaeghe, Annemie Van der Linden, Steven Staelens, Stefanie Dedeurwaerdere
Publikováno v:
NeuroImage: Clinical, Vol 31, Iss , Pp 102701- (2021)
Neuroinflammation is a key component of epileptogenesis, the process leading to acquired epilepsy. In recent years, with the development of non-invasive in vivo positron emission tomography (PET) imaging of translocator protein 18 kDa (TSPO), a marke
Externí odkaz:
https://doaj.org/article/a00c894885164fe5bc81f163bc88c743
Autor:
Daniele Bertoglio, Halima Amhaoul, Annemie Van Eetveldt, Ruben Houbrechts, Sebastiaan Van De Vijver, Idrish Ali, Stefanie Dedeurwaerdere
Publikováno v:
Frontiers in Neurology, Vol 8 (2017)
The aim of epilepsy models is to investigate disease ontogenesis and therapeutic interventions in a consistent and prospective manner. The kainic acid-induced status epilepticus (KASE) rat model is a widely used, well-validated model for temporal lob
Externí odkaz:
https://doaj.org/article/06e2af08c66346ceb477c4b4003f3559
Autor:
Halima Amhaoul, Julie Hamaide, Daniele Bertoglio, Stephanie Nadine Reichel, Jeroen Verhaeghe, Elly Geerts, Debby Van Dam, Peter Paul De Deyn, Samir Kumar-Singh, Andrew Katsifis, Annemie Van Der Linden, Steven Staelens, Stefanie Dedeurwaerdere
Publikováno v:
Neurobiology of Disease, Vol 82, Iss , Pp 526-539 (2015)
Aims: A hallmark in the neuropathology of temporal lobe epilepsy is brain inflammation which has been suggested as both a biomarker and a new mechanistic target for treatments. The translocator protein (TSPO), due to its high upregulation under neuro
Externí odkaz:
https://doaj.org/article/981ebce37ad744c397322f5425b5fff6
Autor:
Annemie Van der Linden, Daniele Bertoglio, Matteo Siano, Joery Goossens, Leonie Wyffels, Halima Amhaoul, Tom Bijnens, Idrish Ali, Stefanie Dedeurwaerdere, Steven Staelens, Elisabeth Jonckers, Jeroen Verhaeghe
Publikováno v:
NeuroImage: Clinical, Vol 31, Iss, Pp 102701-(2021)
NeuroImage: Clinical
NeuroImage : Clinical
NeuroImage: Clinical
NeuroImage : Clinical
Graphical abstract
Highlights • Translocator protein (TSPO) PET imaging identifies different epileptic categories. • TSPO levels at disease onset and chronic disease are unrelated in KASE rats. • TSPO expression changes dynamically during
Highlights • Translocator protein (TSPO) PET imaging identifies different epileptic categories. • TSPO levels at disease onset and chronic disease are unrelated in KASE rats. • TSPO expression changes dynamically during
Autor:
Stefanie Dedeurwaerdere, Halima Amhaoul, Ruben Houbrechts, Idrish Ali, Annemie Van Eetveldt, Sebastiaan Van De Vijver, Daniele Bertoglio
Publikováno v:
Frontiers in Neurology, Vol 8 (2017)
Frontiers in Neurology
Frontiers in neurology
Frontiers in Neurology
Frontiers in neurology
The aim of epilepsy models is to investigate disease ontogenesis and therapeutic interventions in a consistent and prospective manner. The kainic acid-induced status epilepticus (KASE) rat model is a widely used, well-validated model for temporal lob
Autor:
Stephan, Missault, Lore, Peeters, Halima, Amhaoul, David, Thomae, Annemie, Van Eetveldt, Barbara, Favier, Anagha, Thakur, Jeroen, Van Soom, Asla, Pitkänen, Koen, Augustyns, Jurgen, Joossens, Steven, Staelens, Stefanie, Dedeurwaerdere
Publikováno v:
Epilepsia. 58(9)
Urokinase-type plasminogen activator (uPA) and kallikrein-related peptidase 8 (KLK8) are serine proteases that contribute to extracellular matrix (ECM) remodeling after brain injury. They can be labelled with the novel radiotracer [In the KASE model,
Autor:
Stefanie Dedeurwaerdere, Leonie Wyffels, Annemie Van der Linden, Jeroen Verhaeghe, Daniele Bertoglio, Eva Santermans, Niel Hens, Elisabeth Jonckers, Steven Staelens, Halima Amhaoul
Publikováno v:
Brain, behavior, and immunity
ResearcherID
ResearcherID
Brain inflammation is an important factor in the conversion of a healthy brain into an epileptic one, a phenomenon known as epileptogenesis, offering a new entry point for prognostic tools. The development of anti-epileptogenic therapies to treat bef
Autor:
Anagha Thakur, Barbara Favier, Stefanie Dedeurwaerdere, Koen Augustyns, Jeroen Van Soom, Annemie Van Eetveldt, Lore M. Peeters, Jurgen Joossens, Stephan Missault, Halima Amhaoul, Asla Pitkänen, Steven Staelens, David Thomae
Publikováno v:
Epilepsia
Objective: Urokinase-type plasminogen activator (uPA) and kallikrein-related peptidase 8 (KLK8) are serine proteases that contribute to extracellular matrix (ECM) remodeling after brain injury. They can be labelled with the novel radiotracer [In-111]
Autor:
Ceusters Marc Andre, Krystyna Szewczyk, Halima Amhaoul, Stefanie Dedeurwaerdere, Samir Kumar-Singh, Idrish Ali, Marco Mola, Stephan Missault, Annemie Van Eetveldt, Kenny Bielen, Anindya Bhattacharya, Brian Lord, Jason C. Rech
Publikováno v:
Neuropharmacology
Background The available pharmacotherapy for patients with epilepsy primarily address the symptoms and are ineffective in about 40% of patients. Brain inflammation gained support as potential target for developing new therapies, especially the P2X7 r
Autor:
Steven Deleye, Jeroen Verhaeghe, Halima Amhaoul, Sigrid Stroobants, Steven Staelens, Stefanie Dedeurwaerdere
Publikováno v:
2013 IEEE Nuclear Science Symposium and Medical Imaging Conference (2013 NSS/MIC).
Translocator protein (TSPO) PET ligands such as [18F]PBR111 with high specificity for TSPO or formerly the peripheral benzodiazepine (PBR) receptor, are frequently used as a brain inflammation biomarker. In this study a population derived model for t