Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Halil I, Ciftci"'
Autor:
Taha F. S. Ali, Halil I. Ciftci, Mohamed O. Radwan, Eslam Roshdy, Ahmed M. Shawky, Mohammed A. S. Abourehab, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita
Publikováno v:
Pharmaceuticals, Vol 15, Iss 4, p 426 (2022)
The inhibition of glycogen synthase kinase 3β (GSK3β) activity through pharmacological intervention represents a promising approach for treating challenging neurodegenerative disorders like Alzheimer’s disease. Similarly, abnormal tau aggregate a
Externí odkaz:
https://doaj.org/article/511fafb30bc245388d6afa3169bad638
Autor:
Halil I. Ciftci, Mohamed O. Radwan, Belgin Sever, Ahmed K. Hamdy, Safiye Emirdağ, N. Gokce Ulusoy, Ece Sozer, Mustafa Can, Nurettin Yayli, Norie Araki, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita, Mehlika Dilek Altintop
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 10945 (2021)
Glioma, particularly its most malignant form, glioblastoma multiforme (GBM), is the most common and aggressive malignant central nervous system tumor. The drawbacks of the current chemotherapy for GBM have aroused curiosity in the search for targeted
Externí odkaz:
https://doaj.org/article/fbd3afb7d11e41f88f745199e4706c4e
Autor:
Belgin Sever, Mehlika Dilek Altıntop, Ahmet Özdemir, Gülşen Akalın Çiftçi, Doha E. Ellakwa, Hiroshi Tateishi, Mohamed O. Radwan, Mahmoud A. A. Ibrahim, Masami Otsuka, Mikako Fujita, Halil I. Ciftci, Taha F. S. Ali
Publikováno v:
Molecules, Vol 25, Iss 21, p 5190 (2020)
Epidermal growth factor receptor (EGFR) and cyclooxygenase-2 (COX-2) are crucial targetable enzymes in cancer management. Therefore, herein, new 2-[(5-((1H-indol-3-yl)methyl)-1,3,4-oxadiazol-2-yl)thio]-N-(thiazol/benzothiazol-2-yl)acetamides (2a–i)
Externí odkaz:
https://doaj.org/article/f78d9db9d09542498cb068d22fd46ed0
Autor:
Wataru Shida, Hiroshi Tateishi, Yurika Tahara, Mikako Fujita, Doaa Husham Majeed Alsaadi, Masato Watanabe, Ryoko Koga, Mohamed O. Radwan, Halil I. Ciftci, Sevgi Gezici, Yuki Kurauchi, Hiroshi Katsuki, Masami Otsuka, Koji Sugimura, Mikiyo Wada, Nazim Sekeroglu, Takashi Watanabe
Publikováno v:
Molecules, Vol 24, Iss 21, p 3850 (2019)
Despite the development of a range of anti-cancer agents, cancer diagnoses are still increasing in number, remaining a leading cause of death. Anticancer drug treatment is particularly important for leukemia. We screened Turkish plants and found the
Externí odkaz:
https://doaj.org/article/d8a674ffa5ed4eb590077b83ce20ef71
Autor:
Hasan, DeMirci, Yashas, Rao, Gabriele M, Stoffel, Bastian, Vögeli, Kristina, Schell, Aharon, Gomez, Alexander, Batyuk, Cornelius, Gati, Raymond G, Sierra, Mark S, Hunter, E Han, Dao, Halil I, Ciftci, Brandon, Hayes, Fredric, Poitevin, Po-Nan, Li, Manat, Kaur, Kensuke, Tono, David Adrian, Saez, Samuel, Deutsch, Yasuo, Yoshikuni, Helmut, Grubmüller, Tobias J, Erb, Esteban, Vöhringer-Martinez, Soichi, Wakatsuki
Publikováno v:
ACS central science. 8(8)
Enoyl-CoA carboxylases/reductases (ECRs) are some of the most efficient CO
Autor:
Hasan DeMirci, Yashas Rao, Gabriele M. Stoffel, Bastian Vögeli, Kristina Schell, Aharon Gomez, Alexander Batyuk, Cornelius Gati, Raymond G. Sierra, Mark S. Hunter, E. Han Dao, Halil I. Ciftci, Brandon Hayes, Fredric Poitevin, Po-Nan Li, Manat Kaur, Kensuke Tono, David Adrian Saez, Samuel Deutsch, Yasuo Yoshikuni, Helmut Grubmüller, Tobias J. Erb, Esteban Vöhringer-Martinez, Soichi Wakatsuki
Publikováno v:
ACS central science, vol 8, iss 8
ACS Central Science
ACS Central Science
Enoyl-CoA carboxylases/reductases (ECRs) are some of the most efficient CO2-fixing enzymes described to date. However, the molecular mechanisms underlying the extraordinary catalytic activity of ECRs on the level of the protein assembly remain elusiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05fa966255720bcfdf2395cc9e451cb7
https://escholarship.org/uc/item/9064b000
https://escholarship.org/uc/item/9064b000
Autor:
Mohamed O. Radwan, Halil I. Ciftci, Taha F. S. Ali, Doha E. Ellakwa, Ryoko Koga, Hiroshi Tateishi, Akiko Nakata, Akihiro Ito, Minoru Yoshida, Yoshinari Okamoto, Mikako Fujita, Masami Otsuka
Publikováno v:
Molecules, Vol 24, Iss 18, p 3295 (2019)
S-trityl-l-cysteine (STLC) is a well-recognized lead compound known for its anticancer activity owing to its potent inhibitory effect on human mitotic kinesin Eg5. STLC contains two free terminal amino and carboxyl groups that play pivotal roles in b
Externí odkaz:
https://doaj.org/article/2eaaf0241fad4ebb9a6b6d441047fb4e
Autor:
Halil I. Ciftci, Mohamed O. Radwan, Safiye E. Ozturk, N. Gokce Ulusoy, Ece Sozer, Doha E. Ellakwa, Zeynep Ocak, Mustafa Can, Taha F.S. Ali, Howaida I. Abd-Alla, Nurettin Yayli, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita
Publikováno v:
Molecules, Vol 24, Iss 19, p 3535 (2019)
Imatinib, an Abelson (ABL) tyrosine kinase inhibitor, is a lead molecular-targeted drug against chronic myelogenous leukemia (CML). To overcome its resistance and adverse effects, new inhibitors of ABL kinase are needed. Our previous study showed tha
Externí odkaz:
https://doaj.org/article/24998a7a866d47abbbec6170212f581a
Autor:
Halil I Ciftci, Raymond G Sierra, Chun Hong Yoon, Zhen Su, Hiroshi Tateishi, Ryoko Koga, Koiwai Kotaro, Fumiaki Yumoto, Toshiya Senda, Mengling Liang, Soichi Wakatsuki, Masami Otsuka, Mikako Fujita, Hasan DeMirci
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 7, p 1675 (2019)
The Human immunodeficiency virus-1 (HIV-1) matrix (MA) domain is involved in the highly regulated assembly process of the virus particles that occur at the host cell’s plasma membrane. High-resolution structures of the MA domain determined using cr
Externí odkaz:
https://doaj.org/article/db67ecf9967c4cb6be9ba3288569154d
Autor:
Halil I. Ciftci
Publikováno v:
Volume: 7, Issue: 2 290-300
Türk Tarım ve Doğa Bilimleri Dergisi
Türk Tarım ve Doğa Bilimleri Dergisi
α-tomatine is a glycoalkaloid derived from tomato varieties that has been reported to possess various anticancer properties. However, its inhibitory effects on epidermal growth factor receptor is still poorly understood. The aim of this study is to