Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Halie Cook"'
Autor:
Subramanya Karanth, Rakesh Dixit, Patricia C. Ryan, William O. Iverson, Stacey Drabic, Terry O'Day, Simone M. Nicholson, Kerry A. Casey, Michele Gunsior, Stephen Scott, Halie Cook
Publikováno v:
Br J Pharmacol
Background and purpose Inhibition of the T- and B-cell interaction through the CD40/CD40 ligand (L) axis is a favourable approach for inflammatory disease treatment. Clinical studies of anti-CD40L molecules in autoimmune diseases have met challenges
Autor:
Stephen Weasel Scott, Rakesh Dixit, Gianluca Carlesso, Lily Cheng, Joel Leininger, Devon K. Taylor, Halie Cook, Molly Reed, Kathleen McKeever, Katie Streicher, Karma Dacosta, Raffaella Faggioni, Steve Eck, Ronald Herbst, Patricia C. Ryan, Simone M Nicholson
Publikováno v:
Reproductive Toxicology. 74:116-133
MEDI-570 is a fully human afucosylated monoclonal antibody (MAb) against Inducible T-cell costimulator (ICOS), highly expressed on CD4+ T follicular helper (TFH) cells. Effects of MEDI-570 were evaluated in an enhanced pre-postnatal development toxic