Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Haley M Scott"'
Autor:
Haley M. Scott, Mackenzie H. Smith, Aja K. Coleman, Kaitlyn S. Armijo, Morgan J. Chapman, Summer L. Apostalo, Allison R. Wagner, Robert O. Watson, Kristin L. Patrick
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113816- (2024)
Summary: Tight regulation of macrophage immune gene expression is required to fight infection without risking harmful inflammation. The contribution of RNA-binding proteins (RBPs) to shaping the macrophage response to pathogens remains poorly underst
Externí odkaz:
https://doaj.org/article/b8e107d3d69e4d6bae0a464021f10cb9
Autor:
Allison R Wagner, Chi G Weindel, Kelsi O West, Haley M Scott, Robert O Watson, Kristin L Patrick
Publikováno v:
eLife, Vol 11 (2022)
To mount a protective response to infection while preventing hyperinflammation, gene expression in innate immune cells must be tightly regulated. Despite the importance of pre-mRNA splicing in shaping the proteome, its role in balancing immune outcom
Externí odkaz:
https://doaj.org/article/6d3c3ed1193744ab8bd751412b25e522
Autor:
Allison R. Wagner, Haley M. Scott, Kelsi O. West, Krystal J. Vail, Timothy C. Fitzsimons, Aja K. Coleman, Kaitlyn E. Carter, Robert O. Watson, Kristin L. Patrick
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Pathogen sensing via pattern recognition receptors triggers massive reprogramming of macrophage gene expression. While the signaling cascades and transcription factors that activate these responses are well-known, the role of post-transcriptional RNA
Externí odkaz:
https://doaj.org/article/adf17969b3064de09dc3a7b71d0e7eb2
Publikováno v:
Pensar en Movimiento: Revista de Ciencias del Ejercicio y la Salud, Vol 14, Iss 2, Pp 22-43 (2016)
Conforme aumenta la prevalencia de la obesidad en todo el mundo, los investigadores buscan explicaciones para este fenómeno, en particular aquellas relevantes al gasto energético. Se ha identificado que la termogénesis no asociada al ejercicio, ab
Externí odkaz:
https://doaj.org/article/b3a5faeaedbf4465a4913048a8648eb5
Autor:
Kelsi O. West, Haley M. Scott, Sylvia Torres-Odio, A. Phillip West, Kristin L. Patrick, Robert O. Watson
Publikováno v:
Cell Reports, Vol 29, Iss 6, Pp 1594-1609.e5 (2019)
Summary: While transcriptional control of innate immune gene expression is well characterized, almost nothing is known about how pre-mRNA splicing decisions influence, or are influenced by, macrophage activation. Here, we demonstrate that the splicin
Externí odkaz:
https://doaj.org/article/d1e1fb54deb54b45b05c395f599674fb
Autor:
Haley M. Scott, Mackenzie H. Smith, Aja K. Coleman, Allison R. Wagner, Robert O. Watson, Kristin L. Patrick
While the signaling cascades and transcription factors that turn on expression of innate immune genes are well-characterized, the role of RNA binding proteins in activating and sustaining the innate immune response is poorly understood. Members of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::909fdaf0811bcf92952cabaa90184826
https://doi.org/10.1101/2023.05.09.540055
https://doi.org/10.1101/2023.05.09.540055
Publikováno v:
Pensar en Movimiento: Revista de Ciencias del Ejercicio y la Salud, Vol 14, Iss 2, Pp 1-21 (2016)
As the prevalence of obesity rises worldwide, researchers pursue explanations for the phenomenon, particularly those relevant to energy expenditure.Non-exercise activity thermogenesis, or NEAT, has been identified as an inconspicuousbut appreciable c
Externí odkaz:
https://doaj.org/article/013f789c6fbd4f859f76b6857bb0b0f7
Autor:
Chi G. Weindel, Eduardo L. Martinez, Xiao Zhao, Cory J. Mabry, Samantha L. Bell, Krystal J. Vail, Aja K. Coleman, Jordyn J. VanPortfliet, Baoyu Zhao, Allison R. Wagner, Sikandar Azam, Haley M. Scott, Pingwei Li, A. Phillip West, Jason Karpac, Kristin L. Patrick, Robert O. Watson
Publikováno v:
Cell. 185:3214-3231.e23
Although mutations in mitochondrial-associated genes are linked to inflammation and susceptibility to infection, their mechanistic contributions to immune outcomes remain ill-defined. We discovered that the disease-associated gain-of-function allele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa1c9c6f5595b9edba7b01127d4e15a6
https://doi.org/10.1016/j.cell.2022.06.038
https://doi.org/10.1016/j.cell.2022.06.038
Autor:
Kristin L. Patrick, Allison R Wagner, Robert O. Watson, Krystal J Vail, Haley M. Scott, Kelsi O West, Kaitlin Carter
Pathogen sensing via pattern recognition receptors triggers massive reprogramming of macro-phage gene expression. While the signaling cascades and transcription factors that activate these responses are well-known, the role of post-transcriptional RN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cca9f00999165dd60999801fda84f470
https://doi.org/10.1101/2020.12.06.413690
https://doi.org/10.1101/2020.12.06.413690