Nikki Haley: JD Vance's Childless Women Comments 'Not Helpful'.

Autor: Lazarus, Lily Mae

Publikováno v: Daily Beast (New York); 9/8/2024, pN.PAG-N.PAG, 1p

Podocyte-specific KLF6 primes proximal tubule CaMK1D signaling to attenuate diabetic kidney disease.

Autor: Gujarati NA; Division of Nephrology and Hypertension, Department of Medicine, Stony Brook University, Stony Brook, NY, USA., Frimpong BO; Division of Nephrology and Hypertension, Department of Medicine, Stony Brook University, Stony Brook, NY, USA., Zaidi M; Division of Nephrology and Hypertension, Department of Medicine, Stony Brook University, Stony Brook, NY, USA., Bronstein R; Division of Nephrology and Hypertension, Department of Medicine, Stony Brook University, Stony Brook, NY, USA., Revelo MP; Department of Pathology, University of Utah, Salt Lake City, UT, USA., Haley JD; Department of Pharmacology, Stony Brook University, Stony Brook, NY, USA., Kravets I; Division of Endocrinology, Department of Medicine, Stony Brook University, Stony Brook, NY, USA., Guo Y; Division of Nephrology and Hypertension, Department of Medicine, Stony Brook University, Stony Brook, NY, USA., Mallipattu SK; Division of Nephrology and Hypertension, Department of Medicine, Stony Brook University, Stony Brook, NY, USA. sandeep.mallipattu@stonybrookmedicine.edu.; Renal Section, Northport VA Medical Center, Northport, NY, USA. sandeep.mallipattu@stonybrookmedicine.edu.

Publikováno v: Nature communications [Nat Commun] 2024 Sep 13; Vol. 15 (1), pp. 8038. Date of Electronic Publication: 2024 Sep 13.

Neutral ceramidase-active site inhibitor chemotypes and binding modes.

Autor: Coant N; Stony Brook University Cancer Center, Stony Brook University, Stony Brook, NY 11794, USA., Bickel JD; Department of Applied Mathematics, Stony Brook University, Stony Brook, NY 11794, USA., Rahaim R; The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, FL 33458, USA., Otsuka Y; The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, FL 33458, USA., Choi YM; Department of Biochemistry, Stony Brook University, Stony Brook, NY 11794, USA., Xu R; Stony Brook University Cancer Center, Stony Brook University, Stony Brook, NY 11794, USA., Simoes M; Renaissance School of Medicine, Department of Pathology, Stony Brook University, Stony Brook, NY 11794, USA., Cariello C; Renaissance School of Medicine, Department of Pathology, Stony Brook University, Stony Brook, NY 11794, USA., Mao C; Stony Brook University Cancer Center, Stony Brook University, Stony Brook, NY 11794, USA., Saied EM; Chemistry Department, Faculty of Science, Suez Canal University, Ismailia, Egypt., Arenz C; Institute for Chemistry, Humboldt Universität zu Berlin, Brook-Taylor-Str. 2, 12489 Berlin, Germany., Spicer TP; The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, FL 33458, USA., Bannister TD; The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, FL 33458, USA., Tonge PJ; Department of Chemistry, Stony Brook University, Stony Brook, NY 11794, USA., Airola MV; Department of Biochemistry, Stony Brook University, Stony Brook, NY 11794, USA., Scampavia L; The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, FL 33458, USA., Hannun YA; Stony Brook University Cancer Center, Stony Brook University, Stony Brook, NY 11794, USA. Electronic address: yusuf.hannun@stonybrookmedicine.edu., Rizzo RC; Department of Applied Mathematics, Stony Brook University, Stony Brook, NY 11794, USA. Electronic address: robert.rizzo@stonybrook.edu., Haley JD; Stony Brook University Cancer Center, Stony Brook University, Stony Brook, NY 11794, USA; Renaissance School of Medicine, Department of Pathology, Stony Brook University, Stony Brook, NY 11794, USA. Electronic address: john.haley@stonybrookmedicine.edu.

Publikováno v: Bioorganic chemistry [Bioorg Chem] 2023 Oct; Vol. 139, pp. 106747. Date of Electronic Publication: 2023 Jul 27.

Discovery of Novel Bruton's Tyrosine Kinase PROTACs with Enhanced Selectivity and Cellular Efficacy.

Autor: Li YQ; Center for Advanced Study of Drug Action, Stony Brook University, John S. Toll Drive, Stony Brook, New York 11794-3400, United States.; Department of Chemistry, Stony Brook University, John S. Toll Drive, Stony Brook, New York 11794-3400, United States., Lannigan WG; Department of Chemistry, Stony Brook University, John S. Toll Drive, Stony Brook, New York 11794-3400, United States., Davoodi S; Center for Advanced Study of Drug Action, Stony Brook University, John S. Toll Drive, Stony Brook, New York 11794-3400, United States.; Department of Chemistry, Stony Brook University, John S. Toll Drive, Stony Brook, New York 11794-3400, United States., Daryaee F; Center for Advanced Study of Drug Action, Stony Brook University, John S. Toll Drive, Stony Brook, New York 11794-3400, United States.; Department of Chemistry, Stony Brook University, John S. Toll Drive, Stony Brook, New York 11794-3400, United States., Corrionero A; Enzymlogic S.L., QUBE Technology Park, C/ Santiago Grisolía, 2, Madrid 28760, Spain., Alfonso P; Enzymlogic S.L., QUBE Technology Park, C/ Santiago Grisolía, 2, Madrid 28760, Spain., Rodriguez-Santamaria JA; Enzymlogic S.L., QUBE Technology Park, C/ Santiago Grisolía, 2, Madrid 28760, Spain., Wang N; Center for Advanced Study of Drug Action, Stony Brook University, John S. Toll Drive, Stony Brook, New York 11794-3400, United States.; Department of Chemistry, Stony Brook University, John S. Toll Drive, Stony Brook, New York 11794-3400, United States., Haley JD; Department of Pathology, Stony Brook University, John S. Toll Drive, Stony Brook, New York 11794-8691, United States., Tonge PJ; Center for Advanced Study of Drug Action, Stony Brook University, John S. Toll Drive, Stony Brook, New York 11794-3400, United States.; Department of Chemistry, Stony Brook University, John S. Toll Drive, Stony Brook, New York 11794-3400, United States.; Department of Radiology, Stony Brook University, John S. Toll Drive, Stony Brook, New York 11794-3400, United States.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2023 Jun 08; Vol. 66 (11), pp. 7454-7474. Date of Electronic Publication: 2023 May 17.

Development of a 5-FU modified miR-129 mimic as a therapeutic for non-small cell lung cancer.

Autor: Hwang GR; Department of Pathology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794, USA.; Molecular and Cell Biology Graduate Program, Stony Brook University, Stony Brook, NY 11794, USA., Yuen JG; Department of Pathology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794, USA.; Graduate Program in Genetics, Stony Brook University, Stony Brook, NY 11794, USA.; Medical Scientist Training Program, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794, USA., Fesler A; Curamir Therapeutics Inc., Woburn, MA 01801, USA., Farley H; Department of Pathology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794, USA., Haley JD; Department of Pathology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794, USA., Ju J; Department of Pathology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794, USA.; The Northport Veteran's Administration Medical Center, Northport, NY 11768, USA.

Publikováno v: Molecular therapy oncolytics [Mol Ther Oncolytics] 2023 Feb 17; Vol. 28, pp. 277-292. Date of Electronic Publication: 2023 Feb 17 (Print Publication: 2023).