Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Haley Hauck"'
Autor:
Roderick Bronson, Arjun Bhutkar, Peter MK Westcott, Francesc Muyas, Haley Hauck, Olivia C Smith, Nathan Sacks, Zack Ely, Alex M Jaeger, William Rideout, Daniel D Zhang, Mary Clare Beytagh, David Canner, Santiago Naranjo, Abbey Jin, Justin Patten, Amanda M Cruz, Sean-Luc Shanahan, Isidro Cortes-Ciriano, Tyler Jacks
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/f7ec3338903e4e67abbdc5790810ff7e
Autor:
Alex M. Jaeger, JJ Patten, Olivia Smith, Haley Hauck, Ömer H. Yilmaz, Tyler Jacks, George Eng, Peter M. K. Westcott, Jason M. Schenkel, Coralie Backlund, Ryan Elbashir, Darrell J. Irvine, Zackery A. Ely, Daniel Zhang, Nathan J. Sacks, Mary Clare Beytagh
Publikováno v:
Nature Cancer. 2:1071-1085
Immune evasion is a hallmark of cancer and therapies that restore immune surveillance have proven highly effective in cancers with high tumor mutation burden (TMB) (for example, those with microsatellite instability). Whether low TMB cancers, which a
Autor:
Alex M. Jaeger, David Canner, Mary Clare Beytagh, JJ Patten, William M. Rideout, Haley Hauck, Isidro Cortes-Ciriano, Santiago Naranjo, Abbey Jin, Zackery A. Ely, Tyler Jacks, Nathan J. Sacks, Roderick T. Bronson, Peter M. K. Westcott, Francesc Muyas, Arjun Bhutkar, Olivia Smith, Daniel Zhang, Amanda M. Cruz
DNA mismatch repair deficiency (MMRd) is associated with high tumor mutational burden (TMB), increased T cell infiltration, and remarkable responsiveness to immune checkpoint blockade (ICB) therapy1. Nevertheless, about half of MMRd tumors do not res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f615eadc4d03bce6cde32dfce858f582
https://doi.org/10.21203/rs.3.rs-879464/v1
https://doi.org/10.21203/rs.3.rs-879464/v1
Autor:
Alex M. Jaeger, Zackery A. Ely, Peter M. K. Westcott, Amanda M. Cruz, David Canner, Francesc Muyas, Mary Clare Beytagh, JJ Patten, Isidro Cortes-Ciriano, Haley Hauck, Abbey Jin, Roderick T. Bronson, Santiago Naranjo, Daniel Zhang, William M. Rideout, Tyler Jacks, Arjun Bhutkar, Nathan J. Sacks, Olivia Smith
DNA mismatch repair deficiency (MMRd) in human cancer is associated with high tumor mutational burden (TMB), frameshift mutation-derived neoantigens, increased T cell infiltration, and remarkable responsiveness to immune checkpoint blockade (ICB) the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa7b8c8cec8f49449a9abd0ac0e96334
https://doi.org/10.1101/2021.08.24.457572
https://doi.org/10.1101/2021.08.24.457572
Autor:
Daniel Zhang, Peter Westcott, Santiago Naranjo, Haley Hauck, William Rideout, Nate Sacks, Arjun Bhutkar, Justin Patten, Norihiro Goto, Joseph Sedlak, Tyler Jacks
Publikováno v:
Cancer Research. 82:2194-2194
Colorectal cancer (CRC) is the second leading cause of cancer-related deaths worldwide, with a five-year survival rate of only 63% with current treatment regimens. While genetically engineered mouse models (GEMMs) have contributed widely to our under
Autor:
Lindsay M. LaFave, Kevin Meli, Tyler Jacks, Zachary Chiang, Jason D. Buenrostro, Annalisa Okimoto, Fabiana M. Duarte, Peter M. K. Westcott, Aviv Regev, Caleb A. Lareau, Alison Brack, Vinay K. Kartha, Sai Ma, Santiago Naranjo, Haley Hauck, Travis Law, Venkat Sankar, Isabella Del Priore
Publikováno v:
PMC
Regulatory networks that maintain functional, differentiated cell states are often dysregulated in tumor development. Here, we use single-cell epigenomics to profile chromatin state transitions in a mouse model of lung adenocarcinoma (LUAD). We ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09834a7bed67d28152c608f2c4a15859
https://hdl.handle.net/1721.1/133249
https://hdl.handle.net/1721.1/133249
Autor:
Peter M. K. Westcott, Francesc M. Remolar, Olivia Smith, Haley Hauck, Nathan J. Sacks, Zackery A. Ely, Alex M. Jaeger, William M. Rideout, Arjun Bhutkar, Daniel Zhang, Mary C. Beytagh, Roderick T. Bronson, David A. Canner, Santiago Naranjo, Abbey Jin, J. J. Patten, Amanda M. Cruz, Isidro Cortes-Ciriano, Tyler Jacks
Publikováno v:
Cancer Immunology Research. 10:P023-P023
Deficient DNA mismatch repair (dMMR) in human cancer is associated with high tumor mutation burden (TMB), frameshift mutation-derived neoantigens, increased T cell infiltration, and remarkable responsiveness to immune checkpoint blockade (ICB) therap