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pro vyhledávání: '"Haley A. Perlick"'
Autor:
Haley A. Perlick, Harry C. Dietz, Stuart W. Peltz, Maria J. Ruiz-Echevarria, Xia Han, Youmin Weng, Michael D. Ter-Avanesyan, Sergey Paushkin, Kevin Czaplinski
The nonsense-mediated mRNA decay pathway is an example of an evolutionarily conserved surveillance pathway that rids the cell of transcripts that contain nonsense mutations. The product of theUPF1 gene is a necessary component of the putative surveil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41ca7129666c66726a01afc34fb06a46
https://europepmc.org/articles/PMC316864/
https://europepmc.org/articles/PMC316864/
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 93(20)
All eukaryotes that have been studied to date possess the ability to detect and degrade transcripts that contain a premature signal for the termination of translation. This process of nonsense-mediated RNA decay has been most comprehensively studied