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pro vyhledávání: '"Haley A. Klitzing"'
Autor:
Haley A. Klitzing, Mary L. Kraft
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1841:1108-1119
This review discusses the application of time-of-flight secondary ion mass spectrometry (TOF-SIMS) and magnetic sector SIMS with high lateral resolution performed on a Cameca NanoSIMS 50(L) to imaging lipids. The similarities between the two SIMS app
Autor:
Kaiyan Lou, Mary L. Kraft, Haley A. Klitzing, Jessica F. Frisz, Ian D. Hutcheon, Peter K. Weber, Joshua Zimmerberg
Publikováno v:
The Journal of Biological Chemistry
Background: Although cholesterol abundance affects cell function, its distribution within the plasma membrane is not established. Results: Cholesterol is uniformly distributed throughout the plasma membrane and is not enriched within sphingolipid dom
Autor:
Ashley N. Yeager, Robert A. Wilson, Joshua Zimmerberg, Jessica F. Frisz, Mary L. Kraft, Peter K. Weber, Haley A. Klitzing
Publikováno v:
Microscopy and Microanalysis. 21:2397-2398
The plasma membrane is a selectively permeable lipid bilayer that separates cells from their surroundings. Numerous different lipid species, cholesterol, and a variety of different proteins form the plasma membranes of mammalian cells. One class of l
Autor:
Kaiyan Kou, Peter K. Weber, Jessica F. Frisz, Joshua Zimmerberg, Haley A. Klitzing, Mary L. Kraft
Publikováno v:
The FASEB Journal. 27
Autor:
Jessica F. Frisz, Kaiyan Lou, Mary L. Kraft, Vladimir A. Lizunov, Raehyun Kim, Haley A. Klitzing, William P. Hanafin, Kevin J. Carpenter, Ian D. Hutcheon, Joshua Zimmerberg, Robert L. Wilson, Peter K. Weber
Publikováno v:
Proceedings of the National Academy of Sciences. 110
Sphingolipids play important roles in plasma membrane structure and cell signaling. However, their lateral distribution in the plasma membrane is poorly understood. Here we quantitatively analyzed the sphingolipid organization on the entire dorsal su
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 950
Characterization of the distributions of specific proteins and lipids within cellular membranes is currently a major challenge. Advances in secondary ion mass spectrometry (SIMS) now enable the distributions of isotopically labeled lipids within cell
Autor:
Haley A. Klitzing, Vladimir A. Lizunov, Kaiyan Lou, Peter K. Weber, Joshua Zimmerberg, Jessica F. Frisz, Mary L. Kraft
Publikováno v:
The FASEB Journal. 26
Publikováno v:
The FASEB Journal. 26
Autor:
Haley A. Klitzing, William P. Hanafin, Jessica F. Frisz, Mary L. Kraft, Joshua Zimmerberg, Kaiyan Lou, Peter K. Weber
Publikováno v:
Biophysical Journal. 102:26a
Domains enriched with cholesterol and sphingolipids, often referred to as lipid rafts, are believed to be present in the plasma membranes of eukaryotic cells and mediate important cellular functions, including cell signaling and virus budding. Change
Autor:
Haley A. Klitzing, Jessica F. Frisz, Mary L. Kraft, Joshua Zimmerberg, Robert L. Wilson, Peter K. Weber
Publikováno v:
Biophysical Journal. (7):1652-1659
The clusters of the influenza envelope protein, hemagglutinin, within the plasma membrane are hypothesized to be enriched with cholesterol and sphingolipids. Here, we directly tested this hypothesis by using high-resolution secondary ion mass spectro