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of 4
pro vyhledávání: '"Haley A Partlow"'
Autor:
Karthik Siram, Stephanie K. Lathrop, Walid M. Abdelwahab, Rebekah Tee, Clara J. Davison, Haley A. Partlow, Jay T. Evans, David J. Burkhart
Publikováno v:
Vaccines, Vol 12, Iss 1, p 21 (2023)
Despite the availability of effective vaccines against COVID-19, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread worldwide, pressing the need for new vaccines with improved breadth and durability. We developed an adju
Externí odkaz:
https://doaj.org/article/5588703beb6d4da48c23ab455bcdd91b
Autor:
Kristopher K. Short, Stephanie K. Lathrop, Clara J. Davison, Haley A. Partlow, Johnathan A. Kaiser, Rebekah D. Tee, Elizabeth B. Lorentz, Jay T. Evans, David J. Burkhart
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1455 (2022)
A diversity of vaccines is necessary to reduce the mortality and morbidity of SARS-CoV-2. Vaccines must be efficacious, easy to manufacture, and stable within the existing cold chain to improve their availability around the world. Recombinant protein
Externí odkaz:
https://doaj.org/article/dc040770076e4fe8bccc69c38335ffb0
Autor:
Stephanie K Lathrop, Hardik H Amin, Clara J Davison, Haley A Partlow, Elizabeth K Lorentz, David J Burkhart, Jay T Evans
Publikováno v:
The Journal of Immunology. 208:65.32-65.32
Subunit vaccines require an adjuvant, as protein antigens alone provoke a very poor immune response. Liposomes can be used to deliver an adjuvant, particularly when it is an amphipathic molecule such as a toll-like receptor (TLR) 4 agonist. TLR4 enga
Publikováno v:
The Journal of Immunology. 206:30.06-30.06
Adjuvanted subunit vaccines offer improved safety and efficacy over whole inactivated or live attenuated vaccines by incorporating recombinant proteins with highly selective innate immune activators. Selection of an antigen in subunit vaccines can al