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Autor:
Deepa Rungta, Deepak S. Lala, Kay Klausing, Rosemary Cesario, Haleh Razzaghi, Richard A. Heyman, Diane L. Crombie
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 15(8)
The RXR serves as a heterodimer partner for the PPARgamma and the dimer is a molecular target for insulin sensitizers such as the thiazolidinediones. Ligands for either receptor can activate PPAR-dependent pathways via PPAR response elements. Unlike