Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Haleema Shakur-Still"'
Autor:
Temitayo Shokunbi, Haleema Shakur-Still, Raoul Mansukhani, Antonio Belli, Rizwana Chaudhri, Sabariah Faizah Jamaluddin, Amy Brenner, Lauren Frimley, Rashid Jooma, Ian Roberts
Publikováno v:
Wellcome Open Research, Vol 6 (2024)
Background Each year world-wide about 65 million people sustain a mild traumatic brain injury (mTBI). Fatigue is a common and distressing symptom after mTBI. We examine the effect of tranexamic acid (TXA) on fatigue in patients with mTBI using data f
Externí odkaz:
https://doaj.org/article/b272c6112961459fbff68fbb6102378b
Autor:
Amy Brenner, Haleema Shakur-Still, Rizwana Chaudhri, Projestine Muganyizi, Oladapo Olayemi, Monica Arribas, Aasia Kayani, Kiran Javid, Adenike Bello, Ian Roberts, on behalf of the I’M WOMAN Trial Collaborative Group
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-17 (2023)
Abstract Background Postpartum haemorrhage (PPH) causes about 70,000 maternal deaths every year. Tranexamic acid (TXA) is a life-saving treatment for women with PPH. Intravenous (IV) TXA reduces deaths due to PPH by one-third when given within 3 h of
Externí odkaz:
https://doaj.org/article/8dc484fb80c14b22aacb1f64c1b81f67
Autor:
Ian Roberts, Projestine Muganyizi, Oladapo Olayemi, Folasade Adenike Bello, Haleema Shakur-Still, Eni Balogun, Rizwana Chaudhri, Tim Collier
Publikováno v:
Gates Open Research, Vol 7 (2023)
Background: Postpartum haemorrhage (PPH) is responsible for over 50,000 maternal deaths every year. Most of these deaths are in low- and middle-income countries. Tranexamic acid (TXA) reduces bleeding by inhibiting the enzymatic breakdown of fibrin b
Externí odkaz:
https://doaj.org/article/3d54a6ee026b47e5b151d811610e8099
Autor:
Ian Roberts, Oladapo Olayemi, Raoul Mansukhani, Haleema Shakur-Still, Katharine Ker, Luis D. Pacheco, Loïc Sentilhes, Catherine Deneux-Tharaux, George Saade, François-Xavier Ageron, Amy Brenner, Rizwana Chaudhri, Danielle Prowse
Publikováno v:
Gates Open Research, Vol 7 (2023)
Background: Tranexamic acid (TXA) reduces the risk of death and is recommended as a treatment for women with severe postpartum bleeding. There is hope that giving TXA shortly before or immediately after birth could prevent postpartum bleeding. Extend
Externí odkaz:
https://doaj.org/article/1db6e6bc9ace4e1c97397bd36dca8816
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-11 (2022)
Abstract Background Tranexamic acid reduces head injury deaths in patients with CT scan evidence of intracranial bleeding after mild traumatic brain injury (TBI). However, the cost-effectiveness of tranexamic acid for people with mild TBI in the pre-
Externí odkaz:
https://doaj.org/article/8c6b8bef37f047c7a29befa24e3ce66c
Autor:
Amy Brenner, Ian Roberts, Eni Balogun, Folasade Adenike Bello, Rizwana Chaudhri, Charlotte Fleming, Kiran Javaid, Aasia Kayani, Mwansa Ketty Lubeya, Raoul Mansukhani, Oladapo Olayemi, Danielle Prowse, Bellington Vwalika, Haleema Shakur-Still
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-8 (2022)
Abstract Background Postpartum haemorrhage (PPH) is a leading cause of maternal mortality worldwide. Maternal anaemia greatly increases the risk of PPH, and over a third of all pregnant women are anaemic. Because anaemia reduces the oxygen-carrying c
Externí odkaz:
https://doaj.org/article/3d3c8ecbb3664d0cb584240de43aee4e
Autor:
Ian Roberts, Haleema Shakur-Still, Danielle Beaumont, Katharine Ker, Raoul Mansukhani, Monica Arribas
Publikováno v:
BMJ Open, Vol 13, Iss 2 (2023)
Objectives HALT-IT was an international, randomised trial which assessed the effects of tranexamic acid (TXA) in 12 009 patients with gastrointestinal (GI) bleeding. The results found no evidence that TXA reduces death. It is widely accepted that res
Externí odkaz:
https://doaj.org/article/d9461c43fc2d41269f1fd404b578dc31
Publikováno v:
BMJ Open, Vol 12, Iss 7 (2022)
Objective To perform an economic evaluation of tranexamic acid (TXA) versus no-TXA, in addition to current clinical practice, for acute gastrointestinal bleeding, using the results of the HALT-IT trial (NCT01658124), a large randomised controlled tri
Externí odkaz:
https://doaj.org/article/ca3c1cc6336e4f728251472923eb16c8
Autor:
Amy Brenner, Antonio Belli, Rizwana Chaudhri, Timothy Coats, Lauren Frimley, Sabariah Faizah Jamaluddin, Rashid Jooma, Raoul Mansukhani, Peter Sandercock, Haleema Shakur-Still, Temitayo Shokunbi, Ian Roberts, On behalf of the CRASH-3 trial collaborators
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-10 (2020)
Abstract Background The CRASH-3 trial hypothesised that timely tranexamic acid (TXA) treatment might reduce deaths from intracranial bleeding after traumatic brain injury (TBI). To explore the mechanism of action of TXA in TBI, we examined the timing
Externí odkaz:
https://doaj.org/article/5e1fb95c036148cfb03f997289f2cd4e
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-8 (2020)
Abstract Background Early treatment with tranexamic acid may reduce deaths after traumatic brain injury (TBI). In mild and moderate TBI, there is a time to treatment interaction, with early treatment being most beneficial. Time to treatment was recor
Externí odkaz:
https://doaj.org/article/b0037ecf046b4bf4901beba59a32c440