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Nitric oxide, KATP channels and endothelin-1 modulate brain pericyte function, vascular tone and neurovascular coupling

Autor: Zambach, Stefan Andreas, Cai, Changsi, Helms, Hans Christian Cederberg, Hald, Bjørn Olav, Fordsmann, Jonas Christoffer, Nielsen, Reena Murmu, Lønstrup, Micael, Brodin, Birger, Lauritzen, Martin Johannes

Publikováno v: Zambach, S A, Cai, C, Helms, H C C, Hald, B O, Fordsmann, J C, Nielsen, R M, Lønstrup, M, Brodin, B & Lauritzen, M J 2020 ' Nitric oxide, KATP channels and endothelin-1 modulate brain pericyte function, vascular tone and neurovascular coupling ' bioRxiv . https://doi.org/10.1101/2020.06.07.138875

Neurotransmitter-mediated signaling correlates strongly to changes in cerebral blood flow (CBF), and functional neuroimaging relies on the robust coupling between activity and CBF, i.e. neurovascular coupling (NVC). We here reveal that key endothelia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2751::b698a49633bfe1ef2d3b9c6e4aed1f68
https://curis.ku.dk/portal/da/publications/nitric-oxide-katp-channels-and-endothelin1-modulate-brain-pericyte-function-vascular-tone-and-neurovascular-coupling(e58f8884-6520-4afa-96d4-d75ef7965712).html

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Conceptualizing conduction as a pliant vasomotor response: impact of Ca²⁺ fluxes and Ca²⁺ sensitization.

Autor: Hald, Bjørn Olav, Welsh, Donald G.

Publikováno v: American Journal of Physiology: Heart & Circulatory Physiology; Dec2020, Vol. 319 Issue 6, p1190-1201, 12p

Less is more: minimal expression of myoendothelial gap junctions optimizes cell–cell communication in virtual arterioles

Autor: Hald, Bjørn Olav, Jacobsen, Jens Christian Brings, Sandow, Shaun L, Holstein-Rathlou, Niels-Henrik, Welsh, Donald G

Dysfunctional electrical signalling within the arteriolar wall is a major cause of cardiovascular disease. The endothelial cell layer constitutes the primary electrical pathway, co-ordinating contraction of the overlying smooth muscle cell (SMC) laye

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6650eb568c1a48e88e70f95072cd86dd
https://europepmc.org/articles/PMC4146373/