Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hala Zein-Sabatto"'
Autor:
Hala Zein-Sabatto, Dorothy A. Lerit
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Centrosomes are multifunctional organelles tasked with organizing the microtubule cytoskeleton required for genome stability, intracellular trafficking, and ciliogenesis. Contributing to the diversity of centrosome functions are cell cycle-dependent
Externí odkaz:
https://doaj.org/article/b90910a7f38a4a2db8e4ba75c5058b08
Publikováno v:
G3 Genes|Genomes|Genetics. 12
Centrosomes are microtubule-organizing centers that duplicate exactly once to organize the bipolar mitotic spindle required for error-free mitosis. Prior work indicated that Drosophila centrocortin (cen) is required for normal centrosome separation,
VAPB (VPR-1 inC. elegans) is a type-II ER transmembrane protein whose N-terminal Major Sperm Protein domain (MSPd) is cleaved and secreted. Mutations in the MSPd of human VAPB cause impaired secretion and are associated with Amyotrophic Lateral Scler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cffa132121ac1974f94a0f7f83c95719
https://doi.org/10.1101/2021.01.02.425092
https://doi.org/10.1101/2021.01.02.425092
Publikováno v:
Dev Biol
VAMP/synaptobrevin-associated protein B (VAP-B) is a type II ER membrane protein, but its N-terminal MSP domain (MSPd) can be cleaved and secreted. Mutations preventing the cleavage and secretion of MSPd have been implicated in cases of human neurode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e50da9a1f8b9af76099bf0efb37ee85
https://europepmc.org/articles/PMC7856274/
https://europepmc.org/articles/PMC7856274/
C. elegans is a free-living nematode species frequently used to study the molecular genetic pathways that regulate animal development, reproduction, immunity, and lifespan. This species, which consists of hermaphrodites and males, can reproduce by se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f73cb7328f0fabb30e046cb823394d0e
https://doi.org/10.1016/b978-0-12-809633-8.20615-8
https://doi.org/10.1016/b978-0-12-809633-8.20615-8
Autor:
Jeanne N. Jodoin, Poojitha Sitaram, Bruno Reversade, Laura A. Lee, Hala Zein-Sabatto, Ethan Lee, Mohammad Shboul
Publikováno v:
Molecular Biology of the Cell
Molecular biology of the cell, 23(24), 4713-4724. American Society for Cell Biology
Molecular biology of the cell, 23(24), 4713-4724. American Society for Cell Biology
Proper coupling of centrosomes to the nuclear surface at prophase is essential for fidelity of mitotic events. A pool of dynein motors anchored to the nuclear surface mediates this step. The protein Asunder is required in human cultured cells for dyn