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Abstract P3-06-07: ADGRF1 overexpression inhibits tumor growth in vivo by inducing cell cycle arrest in HER2+ breast cancer

Autor: Resel Pereira, Hariprasad Thangavel, Martin Shea, Tamika Mitchell, Carmine De Angelis, Jennifer Torres, Vidyalakshmi Sethunath, Sarmistha Nanda, Raksha Bhat, Rachel Schiff, Lanfang Qin, Hala Yasser, Noor Mazin Abdulkareem, Meghana V. Trivedi

Publikováno v: Cancer Research. 80:P3-06

Background: Adhesion G protein-coupled receptors (GPCRs) form the second largest GPCR subfamily and control many cellular processes involved in cancer. ADGRF1 is an adhesion GPCR overexpressed and gene amplified in HER2+ and triple-negative breast ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::db387f2ead6b636234c0f409fb842df5
https://doi.org/10.1158/1538-7445.sabcs19-p3-06-07

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Abstract 5148: ADGRG1 promotes tumorigenesis, invasion/migration, and cell-cell adhesion in triple-negative breast cancer cells

Autor: Noor Mazin Abdulkareem, Hariprasad Thangavel, Hala Yasser, Meghana V. Trivedi, Raksha Bhat

Publikováno v: Cancer Research. 80:5148-5148

Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer with the highest risk of metastatic recurrence and shortest survival in patients. Chemotherapy, the current standard of treatment for systemic therapy in TNBC, has s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::48e53d65e49d36f0e51c7b4d872ecab8
https://doi.org/10.1158/1538-7445.am2020-5148

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