Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Hala Harony‐Nicolas"'
Autor:
Shai Netser, Guy Nahardiya, Gili Weiss-Dicker, Roei Dadush, Yizhaq Goussha, Shanah Rachel John, Mor Taub, Yuval Werber, Nir Sapir, Yossi Yovel, Hala Harony-Nicolas, Joseph D. Buxbaum, Lior Cohen, Koby Crammer, Shlomo Wagner
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-20 (2022)
Abstract Background Various mammalian species emit ultrasonic vocalizations (USVs), which reflect their emotional state and mediate social interactions. USVs are usually analyzed by manual or semi-automated methodologies that categorize discrete USVs
Externí odkaz:
https://doaj.org/article/27d47b317c6a421bac834d8a41f40079
Autor:
Keerthi Thirtamara Rajamani, Amanda B. Leithead, Michelle Kim, Marie Barbier, Michael Peruggia, Kristi Niblo, Lara Barteczko, Arthur Lefevre, Valery Grinevich, Hala Harony-Nicolas
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Hypothalamic oxytocin (OXT) and arginine-vasopressin (AVP) neurons have been at the center of several physiological and behavioral studies. Advances in viral vector biology and the development of transgenic rodent models have allowed for tar
Externí odkaz:
https://doaj.org/article/bdc99ed306914c47bc827e82cdc68a64
Autor:
Sarah Jacot-Descombes, Neha U. Keshav, Dara L. Dickstein, Bridget Wicinski, William G. M. Janssen, Liam L. Hiester, Edward K. Sarfo, Tahia Warda, Matthew M. Fam, Hala Harony-Nicolas, Joseph D. Buxbaum, Patrick R. Hof, Merina Varghese
Publikováno v:
Molecular Autism, Vol 11, Iss 1, Pp 1-17 (2020)
Abstract Background Deletion or mutations of SHANK3 lead to Phelan–McDermid syndrome and monogenic forms of autism spectrum disorder (ASD). SHANK3 encodes its eponymous scaffolding protein at excitatory glutamatergic synapses. Altered morphology of
Externí odkaz:
https://doaj.org/article/76fed77b88154180aa37dd19e6edee68
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 10 (2018)
The neuropeptide oxytocin (OXT) is a crucial mediator of parturition and milk ejection and a major modulator of various social behaviors, including social recognition, aggression and parenting. In the past decade, there has been significant excitemen
Externí odkaz:
https://doaj.org/article/07d30e40ebca4ecaafec13463bd9fd22
Autor:
Hala Harony-Nicolas, Maya Kay, Johann du Hoffmann, Matthew E Klein, Ozlem Bozdagi-Gunal, Mohammed Riad, Nikolaos P Daskalakis, Sankalp Sonar, Pablo E Castillo, Patrick R Hof, Matthew L Shapiro, Mark G Baxter, Shlomo Wagner, Joseph D Buxbaum
Publikováno v:
eLife, Vol 6 (2017)
Mutations in the synaptic gene SHANK3 lead to a neurodevelopmental disorder known as Phelan-McDermid syndrome (PMS). PMS is a relatively common monogenic and highly penetrant cause of autism spectrum disorder (ASD) and intellectual disability (ID), a
Externí odkaz:
https://doaj.org/article/15f3de3779bb415499c0098f7ef83e2d
Publikováno v:
Neuron. 111:755-756
Autor:
Keerthi Thirtamara Rajamani, Marie Barbier, Arthur Lefevre, Kristi Niblo, Nicholas Cordero, Shai Netser, Valery Grinevich, Shlomo Wagner, Hala Harony-Nicolas
SUMMARYOxytocin plays an important role in modulating social recognition memory. However, the direct implication of oxytocin neurons of the paraventricular nucleus of the hypothalamus (PVH) and their downstream hypothalamic targets in regulating shor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c02e587afa55ac70ca36d6f76f35cb0
https://doi.org/10.1101/2022.05.23.493099
https://doi.org/10.1101/2022.05.23.493099
Autor:
Hala Harony-Nicolas, Carla E. M. Golden, Patrick R. Hof, Victoria X. Wang, Joseph D. Buxbaum, Jason P. Lerch, Yohan Yee
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-14 (2020)
Translational Psychiatry
Translational Psychiatry
Fragile X syndrome (FXS) is a neurodevelopmental disorder that is caused by mutations in the FMR1 gene. Neuroanatomical alterations have been reported in both male and female individuals with FXS, yet the morphological underpinnings of these alterati
Autor:
Jill L. Silverman, Audrey Thurm, Sarah B. Ethridge, Makayla M. Soller, Stela P. Petkova, Ted Abel, Melissa D. Bauman, Edward S. Brodkin, Hala Harony‐Nicolas, Markus Wöhr, Alycia Halladay
Publikováno v:
Genes, brain, and behavior, vol 21, iss 5
Neurodevelopmental disorders (NDDs), including autism spectrum disorder (ASD) and intellectual disability (ID), are pervasive, often lifelong disorders, lacking evidence-based interventions for core symptoms. With no established biological markers, d
Publikováno v:
J Neuroendocrinol
Oxytocin (OXT) neurons of the hypothalamus are at the center of several physiological functions, including milk ejection, uterus contraction, and maternal and social behavior. In lactating females, OXT neurons show a pattern of burst firing and inter