Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hal S. Beilan"'
Synthetic Erythropoietic Proteins: Tuning Biological Performance by Site-Specific Polymer Attachment
Autor:
E. Neil Cagle, Maia Carnevali, John W. Adamson, Vincent Gueriguian, Carlos E. Bozzini, Gerd G. Kochendoerfer, Sonya Cressman, James A. Bradburne, Ada Kung, M. Con Wiedeke, Heather Porter, Laura Savatski, Stephen M. Stratton, Feng Mao, Haiyan Shao, Donald W. Low, Stephen B. H. Kent, Shiah-Yun Chen, Peter J. Keogh, Hal S. Beilan
Publikováno v:
Chemistry & Biology. 12(3):371-383
SummaryChemical synthesis in combination with precision polymer modification allows the systematic exploration of the effect of protein properties, such as charge and hydrodynamic radius, on potency using defined, homogeneous conjugates. A series of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9455f5c2578524928fd3f5cbf800ce2c
Publikováno v:
Bioorganic Chemistry. 15:109-114
Cystine labeled in the 3-position with both 13C and two deuteriums was prepared in 17% overall yield from Ba13CO3 by an aminomalonate condensation with D2CO-13C. The labeled formaldehyde precursor was prepared by catalytic oxidation of 13CD3OH, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21fea4a64cfed46a481f04dd11837d63
https://doi.org/10.1016/0045-2068(87)90012-5
https://doi.org/10.1016/0045-2068(87)90012-5
Publikováno v:
The Journal of Organic Chemistry. 39:2148-2152
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbb24c5ccff887ae3344937da4a05057
https://doi.org/10.1021/jo00929a003
https://doi.org/10.1021/jo00929a003
Publikováno v:
Analytical biochemistry. 128(1)
Protein obtained from several strains of Escherichia coli grown in the presence of [3,3′- 14 C]cystine contained the radiolabel in nearly all the other amino acids, suggesting catabolism of cysteine to pyruvic acid. Utilization in amino acid synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b40a1efdbf5d8cfe9d302e181cde664c
https://pubmed.ncbi.nlm.nih.gov/6342463
https://pubmed.ncbi.nlm.nih.gov/6342463
Publikováno v:
Peptides ISBN: 9789401095976
Peptides
Peptides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4cdbc5502931d6c587961bfa7e3c97f
https://doi.org/10.1007/978-94-010-9595-2_57
https://doi.org/10.1007/978-94-010-9595-2_57
