Injury to Cone Synapses by Retinal Detachment: Differences from Rod Synapses and Protection by ROCK Inhibition.

Autor: Townes-Anderson E; Department of Pharmacology, Physiology and Neuroscience, Rutgers New Jersey Medical School, 185 South Orange Avenue, Newark, NJ 07103, USA., Halász É; Department of Pharmacology, Physiology and Neuroscience, Rutgers New Jersey Medical School, 185 South Orange Avenue, Newark, NJ 07103, USA., Sugino I; Institute of Ophthalmology and Visual Science, Rutgers New Jersey Medical School, 90 Bergen Street, Newark, NJ 07103, USA., Davidow AL; Department of Biostatistics, New York University School of Global Public Health, 708 Broadway, New York, NY 10003, USA., Frishman LJ; Department of Vision Sciences, College of Optometry, University of Houston, Martin Luther King Blvd, Houston, TX 77204, USA., Fritzky L; Cellular Imaging and Histology Core, Rutgers New Jersey Medical School, 205 South Orange Avenue, Newark, NJ 07103, USA., Yousufzai FAK; Cellular Imaging and Histology Core, Rutgers New Jersey Medical School, 205 South Orange Avenue, Newark, NJ 07103, USA., Zarbin M; Institute of Ophthalmology and Visual Science, Rutgers New Jersey Medical School, 90 Bergen Street, Newark, NJ 07103, USA.

Publikováno v: Cells [Cells] 2023 May 27; Vol. 12 (11). Date of Electronic Publication: 2023 May 27.

ROCK inhibition reduces morphological and functional damage to rod synapses after retinal injury.

Autor: Halász É; Department of Pharmacology, Physiology and Neuroscience, Rutgers New Jersey Medical School, 185 South Orange Avenue, Newark, NJ, 07103, USA., Zarbin MA; Institute of Ophthalmology and Visual Science, Rutgers New Jersey Medical School, 90 Bergen Street, Newark, NJ, 07103, USA., Davidow AL; Department of Biostatistics and Epidemiology, Rutgers School of Public Health, 683 Hoes Lane West, Piscataway, NJ, 08854, USA., Frishman LJ; College of Optometry, University of Houston, 3507 Cullen Blvd, Houston, TX, 77204, USA., Gombkoto P; Center for Molecular and Behavioral Neuroscience, Rutgers University, 197 University Avenue, Newark, NJ, 07102, USA., Townes-Anderson E; Department of Pharmacology, Physiology and Neuroscience, Rutgers New Jersey Medical School, 185 South Orange Avenue, Newark, NJ, 07103, USA. andersel@njms.rutgers.edu.; Institute of Ophthalmology and Visual Science, Rutgers New Jersey Medical School, 90 Bergen Street, Newark, NJ, 07103, USA. andersel@njms.rutgers.edu.

Publikováno v: Scientific reports [Sci Rep] 2021 Jan 12; Vol. 11 (1), pp. 692. Date of Electronic Publication: 2021 Jan 12.

Retinal damage extends beyond the border of the detached retina in fovea-on retinal detachment.

Autor: Ng HJ; The Rotterdam Eye Hospital, Rotterdam Ophthalmic Institute, Rotterdam, The Netherlands., Vermeer KA; The Rotterdam Eye Hospital, Rotterdam Ophthalmic Institute, Rotterdam, The Netherlands., La Heij EC; The Rotterdam Eye Hospital, Vitreoretinal Surgery, Rotterdam, The Netherlands., Kuip CP; The Rotterdam Eye Hospital, Rotterdam Ophthalmic Institute, Rotterdam, The Netherlands., van Meurs JC; The Rotterdam Eye Hospital, Vitreoretinal Surgery, Rotterdam, The Netherlands.; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands.

Publikováno v: Acta ophthalmologica [Acta Ophthalmol] 2024 May; Vol. 102 (3), pp. 285-295. Date of Electronic Publication: 2023 May 23.

Small-Molecule-Directed Endogenous Regeneration of Visual Function in a Mammalian Retinal Degeneration Model.

Autor: Mokady, Daphna¹ (AUTHOR) daphna@endogena.com, Charish, Jason¹ (AUTHOR), Barretto-Burns, Patrick¹ (AUTHOR), Grisé, Kenneth N.² (AUTHOR), Coles, Brenda L. K.² (AUTHOR), Raab, Susanne³ (AUTHOR), Ortin-Martinez, Arturo¹ (AUTHOR), Müller, Alex³ (AUTHOR), Fasching, Bernhard³ (AUTHOR), Jain, Payal¹ (AUTHOR), Drukker, Micha³ (AUTHOR), van der Kooy, Derek² (AUTHOR), Steger, Matthias³ (AUTHOR) daphna@endogena.com

Publikováno v: International Journal of Molecular Sciences. Feb2024, Vol. 25 Issue 3, p1521. 19p.

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