Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Hakwoo Lee"'
Autor:
Farhia Kabeer, Hoa Tran, Mirela Andronescu, Gurdeep Singh, Hakwoo Lee, Sohrab Salehi, Beixi Wang, Justina Biele, Jazmine Brimhall, David Gee, Viviana Cerda, Ciara O’Flanagan, Teresa Algara, Takako Kono, Sean Beatty, Elena Zaikova, Daniel Lai, Eric Lee, Richard Moore, Andrew J. Mungall, IMAXT Consortium, Marc J. Williams, Andrew Roth, Kieran R. Campbell, Sohrab P. Shah, Samuel Aparicio
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-32 (2024)
Abstract Background The encoding of cell intrinsic drug resistance states in breast cancer reflects the contributions of genomic and non-genomic variations and requires accurate estimation of clonal fitness from co-measurement of transcriptomic and g
Externí odkaz:
https://doaj.org/article/49d08f6904d04bb2b5f01bd4a5faa66b
Autor:
Nicholas Ceglia, Diljot Grewal, Justina Biele, Weiner Ac, Brimhall J, Peter Eirew, Samuel Aparicio, Ciara H. O'Flanagan, Havasov E, Masud T, Hakwoo Lee, Beatty S, Samantha Leung, Florian Uhlitz, Abrams D, Ignacio Vázquez-García, Marc J Williams, Damian Yap, Daniel Lai, Salehi S, Sohrab P. Shah, Ting J, Wang B, Farhia Kabeer, Nicole Rusk, Bojilova, Tyler Funnell, Jenifer Pham, Andrew McPherson
Cancer genomes exhibit extensive chromosomal copy number changes and structural variation, yet how allele specific alterations drive cancer genome evolution remains unclear. Here, through application of a new computational approach we report allele s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfe906a55569752a1cc9c03c621e85ce
https://doi.org/10.1101/2021.06.04.447031
https://doi.org/10.1101/2021.06.04.447031
Autor:
Beatty S, Britta Weigelt, Havasov E, Douglas Jm, Beixi Wang, Samuel Aparicio, Steven McKinney, Samantha Leung, Hakwoo Lee, Brimhall J, Marc J Williams, Yang Li, Sohrab P. Shah, Justina Biele, Jamie L. P. Lim, Funnell T, Da Cruz Paula A, Ciara H. O'Flanagan, Andrew McPherson, Damian Yap, Nicholas Ceglia, Diljot Grewal, Weiner Ac, Sarah H. Kim, Allen Zhang, Ruiz de Algara T, Lee, Cerda Llanos, Liu Yf, Peter Eirew, Jorge S. Reis-Filho, Dmitriy Zamarin, Abrams D, Tehmina Masud, Daniel Lai, Bojilova, Richard A. Moore, Xu H, Farhia Kabeer, Nicole Rusk, Florian Uhlitz, Jerome Ting, Jenifer Pham
Structural genome alterations are determinants of cancer ontogeny and therapeutic response. While bulk genome sequencing has enabled delineation of structural variation (SV) mutational processes which generate patterns of DNA damage, we have little u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbca175098a6792741c75961dca47af5
https://doi.org/10.1101/2021.06.03.446999
https://doi.org/10.1101/2021.06.03.446999
Autor:
Tyler, Funnell, Ciara H, O'Flanagan, Marc J, Williams, Andrew, McPherson, Steven, McKinney, Farhia, Kabeer, Hakwoo, Lee, Sohrab, Salehi, Ignacio, Vázquez-García, Hongyu, Shi, Emily, Leventhal, Tehmina, Masud, Peter, Eirew, Damian, Yap, Allen W, Zhang, Jamie L P, Lim, Beixi, Wang, Jazmine, Brimhall, Justina, Biele, Jerome, Ting, Vinci, Au, Michael, Van Vliet, Yi Fei, Liu, Sean, Beatty, Daniel, Lai, Jenifer, Pham, Diljot, Grewal, Douglas, Abrams, Eliyahu, Havasov, Samantha, Leung, Viktoria, Bojilova, Richard A, Moore, Nicole, Rusk, Florian, Uhlitz, Nicholas, Ceglia, Adam C, Weiner, Elena, Zaikova, J Maxwell, Douglas, Dmitriy, Zamarin, Britta, Weigelt, Sarah H, Kim, Arnaud, Da Cruz Paula, Jorge S, Reis-Filho, Spencer D, Martin, Yangguang, Li, Hong, Xu, Teresa Ruiz, de Algara, So Ra, Lee, Viviana Cerda, Llanos, David G, Huntsman, Jessica N, McAlpine, Sohrab P, Shah, Pu, Zheng
Publikováno v:
Nature. 612(7938)
How cell-to-cell copy number alterations that underpin genomic instability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::baaf3b0746b71635075b84546a6965ab
https://pubmed.ncbi.nlm.nih.gov/36289342
https://pubmed.ncbi.nlm.nih.gov/36289342
Autor:
Tomo, Osako, Hakwoo, Lee, Gulisa, Turashvili, Derek, Chiu, Steven, McKinney, Stacey E P, Joosten, Darcy, Wilkinson, Torsten O, Nielsen, Wilbert, Zwart, Joanne T, Emerman, Connie J, Eaves, Carlos, Caldas, Samuel, Aparicio
Publikováno v:
Nature cancer. 1(5)
The magnitude and scope of intrinsic age-correlated and host endocrine age-correlated gene expression in breast cancer is not well understood. From age-correlated gene expression in 3,071 breast cancer transcriptomes and epithelial protein expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4dab07a30d5065f4c64643d27fb5f1c2
https://pubmed.ncbi.nlm.nih.gov/35121983
https://pubmed.ncbi.nlm.nih.gov/35121983
Autor:
Richard D. Moore, Simong Song, Teresa Ruiz de Algara, Ciara H. O'Flanagan, Biexi Wang, So Ra Lee, Samuel Aparicio, Sohrab P. Shah, Andrew J. Mungall, Justina Biele, Hakwoo Lee, Patricia Ye, Michael Yuen, Jenifer Pham, Farhia Kabeer, Brimhall J, Daniel Lai
Publikováno v:
Cancer Research. 80:PD8-05
Introduction Breast cancer is the most common cancer in female and triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer which shows high rate of recurrence and metastasis. Malignant cells that comprise primary tumor ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11de601fd22ccfc405f72595604e42ef
https://doi.org/10.1158/1538-7445.sabcs19-pd8-05
https://doi.org/10.1158/1538-7445.sabcs19-pd8-05
Autor:
Hakwoo Lee, Duane G. Wombolt, Keith H. Johnson, Melville Williams, Norman Ende, Charles B. Currier
Publikováno v:
Human Pathology. 13:272-278
Of 189 unsuccessful renal transplant cases, eight were selected for retrospective analysis because they had been classified histologically as “chronic rejection with marked vascular changes” even though they had been removed less than 60 days aft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e57fd30bb883b478b1f01ced1738a70
https://doi.org/10.1016/s0046-8177(82)80184-6
https://doi.org/10.1016/s0046-8177(82)80184-6