Targeting Endoglin Expressing Cells in the Tumor Microenvironment Does Not Inhibit Tumor Growth in a Pancreatic Cancer Mouse Model

Autor: Schoonderwoerd MJ, Hakuno SK, Sassen M, Kuhlemaijer EB, Paauwe M, Slingerland M, Fransen MF, Hawinkels LJ

Publikováno v: OncoTargets and Therapy, Vol Volume 14, Pp 5205-5220 (2021)

Mark JA Schoonderwoerd,1,* Sarah K Hakuno,1,* Martijn Sassen,1 Eleonore B Kuhlemaijer,1 Madelon Paauwe,1 Marije Slingerland,2 Marieke F Fransen,3 Lukas JAC Hawinkels1 1Department of Gastroenterology-Hepatology, Leiden University Medical Cente

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doajarticles::b2238ab009cd3f2d78fe550252b1352d
https://www.dovepress.com/targeting-endoglin-expressing-cells-in-the-tumor-microenvironment-does-peer-reviewed-fulltext-article-OTT

Dynamic Visualization of TGF-β/SMAD3 Transcriptional Responses in Single Living Cells.

Autor: Marvin DL; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands., You L; Oncode Institute and Department of Molecular Genetics, Erasmus University Medical Center, Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands., Bornes L; Oncode Institute and Department of Molecular Pathology, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands., van Dinther M; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands., Peters N; UMC Utrecht Cancer Center, University Medical Center Utrecht, Utrecht University, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands., Dang H; Department of Gastroenterology and Hepatology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands., Hakuno SK; Department of Gastroenterology and Hepatology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands., Hornsveld M; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.; Department of Gastroenterology and Hepatology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands., Kranenburg O; UMC Utrecht Cancer Center, University Medical Center Utrecht, Utrecht University, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands., van Rheenen J; Oncode Institute and Department of Molecular Pathology, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands., Rohling JHT; Department of Cell and Chemical Biology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands., Chien MP; Oncode Institute and Department of Molecular Genetics, Erasmus University Medical Center, Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands., Ten Dijke P; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands., Ritsma L; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.

Publikováno v: Cancers [Cancers (Basel)] 2022 May 19; Vol. 14 (10). Date of Electronic Publication: 2022 May 19.

Stromal Cells in the Pathogenesis of Inflammatory Bowel Disease.

Autor: Barnhoorn MC; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands., Hakuno SK; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands., Bruckner RS; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland., Rogler G; Department of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland., Hawinkels LJAC; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands., Scharl M; Department of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland.

Publikováno v: Journal of Crohn's & colitis [J Crohns Colitis] 2020 Jul 30; Vol. 14 (7), pp. 995-1009.

Unravelling the role of intratumoral bacteria in digestive system cancers: current insights and future perspectives.

Autor: Lu, Weiqin¹ (AUTHOR), Aihaiti, Aihemaitijiang² (AUTHOR), Abudukeranmu, Paziliya² (AUTHOR), Liu, Yajun² (AUTHOR), Gao, Huihui³ (AUTHOR) huihui_gao@126.com

Publikováno v: Journal of Translational Medicine. 6/7/2024, Vol. 22 Issue 1, p1-18. 18p.

Inflammatory tissue priming: novel insights and therapeutic opportunities for inflammatory rheumatic diseases.

Autor: Hoffmann, Markus H., Kirchner, Henriette, Krönke, Gerhard, Riemekasten, Gabriela, Bonelli, Michael

Publikováno v: Annals of the Rheumatic Diseases; Oct2024, Vol. 83 Issue 10, p1233-1253, 21p