Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Autor: Ehret, Georg B., Munroe, Patricia B., Rice, Kenneth M., Bochud, Murielle, Johnson, Andrew D., Chasman, Daniel I., Smith, Albert V., Tobin, Martin D., Verwoert, Germaine C., Hwang, Shih-Jen, Pihur, Vasyl, Vollenweider, Peter, O'Reilly, Paul F., Amin, Najaf, Bragg-Gresham, Jennifer L., Teumer, Alexander, Glazer, Nicole L., Launer, Lenore, Zhao, Jing Hua, Aulchenko, Yurii, Heath, Simon, Sober, Siim, Parsa, Afshin, Luan, Jian'an, Arora, Pankaj, Dehghan, Abbas, Zhang, Feng, Lucas, Gavin, Hicks, Andrew A., Jackson, Anne U., Peden, John F., Tanaka, Toshiko, Wild, Sarah H., Rudan, Igor, Igl, Wilmar, Milaneschi, Yuri, Parker, Alex N., Fava, Cristiano, Chambers, John C., Fox, Ervin R., Kumari, Meena, Go, Min Jin, van der Harst, Pim, Kao, Wen Hong Linda, Sjögren, Marketa, Vinay, D. G., Alexander, Myriam, Tabara, Yasuharu, Shaw-Hawkins, Sue, Whincup, Peter H., Liu, Yongmei, Shi, Gang, Kuusisto, Johanna, Tayo, Bamidele, Seielstad, Mark, Sim, Xueling, Hoang Nguyen, Khanh-Dung, Lehtimäki, Terho, Matullo, Giuseppe, Wu, Ying, Gaunt, Tom R., Charlotte Onland-Moret, N., Cooper, Matthew N., Platou, Carl G. P., Org, Elin, Hardy, Rebecca, Dahgam, Santosh, Palmen, Jutta, Vitart, Veronique, Braund, Peter S., Kuznetsova, Tatiana, Uiterwaal, Cuno S. P. M., Adeyemo, Adebowale, Palmas, Walter, Campbell, Harry, Ludwig, Barbara, Tomaszewski, Maciej, Tzoulaki, Ioanna, Palmer, Nicholette D., Aspelund, Thor, Garcia, Melissa, Chang, Yen-Pei C., O'Connell, Jeffrey R., Steinle, Nanette I., Grobbee, Diederick E., Arking, Dan E., Kardia, Sharon L., Morrison, Alanna C., Hernandez, Dena, Najjar, Samer, McArdle, Wendy L., Hadley, David, Brown, Morris J., Connell, John M., Hingorani, Aroon D., Day, Ian N. M., Lawlor, Debbie A., Beilby, John P., Lawrence, Robert W., Clarke, Robert, Hopewell, Jemma C., Ongen, Halit, Dreisbach, Albert W., Li, Yali, Hunter Young, J., Bis, Joshua C., Kähönen, Mika, Viikari, Jorma, Adair, Linda S., Lee, Nanette R., Chen, Ming-Huei, Olden, Matthias, Pattaro, Cristian, Bolton, Judith A Hoffman, Köttgen, Anna, Bergmann, Sven, Mooser, Vincent, Chaturvedi, Nish, Frayling, Timothy M., Islam, Muhammad, Jafar, Tazeen H., Erdmann, Jeanette, Kulkarni, Smita R., Bornstein, Stefan R., Grässler, Jürgen, Groop, Leif, Voight, Benjamin F., Kettunen, Johannes, Howard, Philip, Taylor, Andrew, Guarrera, Simonetta, Ricceri, Fulvio, Emilsson, Valur, Plump, Andrew, Barroso, Inês, Khaw, Kay-Tee, Weder, Alan B., Hunt, Steven C., Sun, Yan V., Bergman, Richard N., Collins, Francis S., Bonnycastle, Lori L., Scott, Laura J., Stringham, Heather M., Peltonen, Leena, Perola, Markus, Vartiainen, Erkki, Brand, Stefan-Martin, Staessen, Jan A., Wang, Thomas J., Burton, Paul R., Artigas, Maria Soler, Dong, Yanbin, Snieder, Harold, Wang, Xiaoling, Zhu, Haidong, Lohman, Kurt K., Rudock, Megan E., Heckbert, Susan R., Smith, Nicholas L., Wiggins, Kerri L., Doumatey, Ayo, Shriner, Daniel, Veldre, Gudrun, Viigimaa, Margus, Kinra, Sanjay, Prabhakaran, Dorairaj, Tripathy, Vikal, Langefeld, Carl D., Rosengren, Annika, Thelle, Dag S., Corsi, Anna Maria, Singleton, Andrew, Forrester, Terrence, Hilton, Gina, McKenzie, Colin A., Salako, Tunde, Iwai, Naoharu, Kita, Yoshikuni, Ogihara, Toshio, Ohkubo, Takayoshi, Okamura, Tomonori, Ueshima, Hirotsugu, Umemura, Satoshi, Eyheramendy, Susana, Meitinger, Thomas, Wichmann, H. -Erich, Cho, Yoon Shin, Kim, Hyung-Lae, Lee, Jong-Young, Scott, James, Sehmi, Joban S., Zhang, Weihua, Hedblad, Bo, Nilsson, Peter, Smith, George Davey, Wong, Andrew, Narisu, Narisu, Stančáková, Alena, Raffel, Leslie J., Yao, Jie, Kathiresan, Sekar, O'Donnell, Christopher J., Schwartz, Stephen M., Arfan Ikram, M., Longstreth Jr. , W. T., Mosley, Thomas H., Seshadri, Sudha, Shrine, Nick R. G., Wain, Louise V., Morken, Mario A., Swift, Amy J., Laitinen, Jaana, Prokopenko, Inga, Zitting, Paavo, Cooper, Jackie A., Humphries, Steve E., Danesh, John, Rasheed, Asif, Goel, Anuj, Hamsten, Anders, Watkins, Hugh, Bakker, Stephan J. L., van Gilst, Wiek H., Janipalli, Charles S., Radha Mani, K., Yajnik, Chittaranjan S., Hofman, Albert, Mattace-Raso, Francesco U. S., Oostra, Ben A., Demirkan, Ayse, Isaacs, Aaron, Rivadeneira, Fernando, Lakatta, Edward G., Orru, Marco, Scuteri, Angelo, Ala-Korpela, Mika, Kangas, Antti J., Lyytikäinen, Leo-Pekka, Soininen, Pasi, Tukiainen, Taru, Würtz, Peter, Twee-HeeOng, Rick, Dörr, Marcus, Kroemer, Heyo K., Völker, Uwe, Völzke, Henry, Galan, Pilar, Hercberg, Serge, Lathrop, Mark, Zelenika, Diana, Deloukas, Panos, Mangino, Massimo, Spector, Tim D., Zhai, Guangju, Meschia, James F., Nalls, Michael A., Sharma, Pankaj, Terzic, Janos, Kranthi Kumar, M. V., Denniff, Matthew, Zukowska-Szczechowska, Ewa, Wagenknecht, Lynne E., Fowkes, F. Gerald R., Charchar, Fadi J., Schwarz, Peter E. H., Hayward, Caroline, Guo, Xiuqing, Rotimi, Charles, Bots, Michiel L., Brand, Eva, Samani, Nilesh J., Polasek, Ozren, Talmud, Philippa J., Nyberg, Fredrik, Kuh, Diana, Laan, Maris, Hveem, Kristian, Palmer, Lyle J., van der Schouw, Yvonne T., Casas, Juan P., Mohlke, Karen L., Vineis, Paolo, Raitakari, Olli, Ganesh, Santhi K., Wong, Tien Y., Shyong Tai, E., Cooper, Richard S., Laakso, Markku, Rao, Dabeeru C., Harris, Tamara B., Morris, Richard W., Dominiczak, Anna F., Kivimaki, Mika, Marmot, Michael G., Miki, Tetsuro, Saleheen, Danish, Chandak, Giriraj R., Coresh, Josef, Navis, Gerjan, Salomaa, Veikko, Han, Bok-Ghee, Zhu, Xiaofeng, Kooner, Jaspal S., Melander, Olle, Ridker, Paul M., Bandinelli, Stefania, Gyllensten, Ulf B., Wright, Alan F., Wilson, James F., Ferrucci, Luigi, Farrall, Martin, Tuomilehto, Jaakko, Pramstaller, Peter P., Elosua, Roberto, Soranzo, Nicole, Sijbrands, Eric J. G., Altshuler, David, Loos, Ruth J. F., Shuldiner, Alan R., Gieger, Christian, Meneton, Pierre, Uitterlinden, Andre G., Wareham, Nicholas J., Gudnason, Vilmundur, Rotter, Jerome I., Rettig, Rainer, Uda, Manuela, Strachan, David P., Witteman, Jacqueline C. M., Hartikainen, Anna-Liisa, Beckmann, Jacques S., Boerwinkle, Eric, Vasan, Ramachandran S., Boehnke, Michael, Larson, Martin G., Järvelin, Marjo-Riitta, Psaty, Bruce M., Abecasis, Gonçalo R., Chakravarti, Aravinda, Elliott, Paul, van Duijn, Cornelia M., Newton-Cheh, Christopher, Levy, Daniel, Caulfield, Mark J., Johnson, Toby, Tang H, Knowles J, Hlatky M, Fortmann S, Assimes TL, Quertermous T, Go A, Iribarren C, Absher D, Risch N, Meyers R, Sidney S, Ziegler A, Schillert A, Bickel C, Sinning C, Rupprecht HJ, Lackner K, Wild P, Schnabel R, Blankenberg S, Zeller T, Münzel T, Perret C, Cambien F, Tiret L, Nicaud V, Proust C, Dehghan A, Hofman A, Uitterlinden A, van Duijn C, Levy D, Whitteman J, Cupples LA, Demissie-Banjaw S, Ramachandran V, Smith A, Gudnason V, Boerwinkle E, Folsom A, Morrison A, Psaty BM, Chen IY, Rotter JI, Bis J, Volcik K, Rice K, Taylor KD, Marciante K, Smith N, Glazer N, Heckbert S, Harris T, Lumley T, Kong A, Thorleifsson G, Thorgeirsson G, Holm H, Gulcher JR, Stefansson K, Andersen K, Gretarsdottir S, Thorsteinsdottir U, Preuss M, Schreiber S, Meitinger T, König IR, Lieb W, Hengstenberg C, Schunkert H, Erdmann J, Fisher M, Grosshennig A, Medack A, Stark K, Linsel-Nitschke P, Bruse P, Aherrahrou Z, Peters A, Loley C, Willenborg C, Nahrstedt J, Freyer J, Gulde S, Doering A, Meisinger C, Wichmann HE, Klopp N, Illig T, Meinitzer A, Tomaschitz A, Halperin E, Dobnig H, Scharnagl H, Kleber M, Laaksonen R, Pilz S, Grammer TB, Stojakovic T, Renner W, März W, Böhm BO, Winkelmann BR, Winkler K, Hoffmann M, O'Donnell CJ, Voight BF, Altshuler D, Siscovick DS, Musunuru K, Peltonen L, Barbalic M, Melander O, Elosua R, Kathiresan S, Schwartz SM, Salomaa V, Guiducci C, Burtt N, Gabriel SB, Stewart AF, Wells GA, Chen L, Jarinova O, Roberts R, McPherson R, Dandona S, Pichard AD, Rader DJ, Devaney J, Lindsay JM, Kent KM, Qu L, Satler L, Burnett MS, Li M, Reilly MP, Wilensky R, Waksman R, Epstein S, Mattha W, Knouf CW, Waterworth DM, Hakonarson HH, Walker M, Mooser V, Hall AS, Balmforth AJ, Wright BJ, Nelson C, Thompson JR, Samani NJ, Braund PS, Ball SG, Smith NL, Felix JF, Morrison AC, Demissie S, Glazer NL, Loehr LR, Rosamond WD, Rivadeneira F, Bis JC, Folsom AR, Benjamin E, Aulchenko YS, Haritunians T, Couper D, Murabito J, Wang YA, Stricker B, Gottdiener JS, Chang PP, Wang TJ, Rice KM, Heckbert SR, Fox ER, Uitterlinden AG, Willerson JT, van Duijn CM, Witteman JC, Vasan RS, Köttgen A, Pattaro C, Böger CA, Fuchsberger C, Olden M, Parsa A, Gao X, Yang Q, Smith AV, O'Connell JR, Schmidt H, Tanaka T, Isaacs A, Ketkar S, Hwang SJ, Johnson A, Teumer A, Paré G, Atkinson EJ, Lohman K, Cornelis MC, Probst-Hensch NM, Kronenberg F, Tönjes A, Hayward C, Aspelund T, Eiriksdottir G, Launer LJ, Harris TB, Rampersaud E, Mitchell BD, Arking DE, Struchalin M, Cavalieri M, Singleton A, Giallauria, Francesco, Metter J, de Boer J, Siscovick D, Zillikens MC, Oostra BA, Feitosa M, Province M, de Andrade M, Turne ST, Wild PS, Schnabel RB, Wilde S, Munzel TF, Leak TS, Koenig W, Zgaga L, Zemunik T, Kolcic I, Minelli C, Hu FB, Johansson A, Igl W, Zaboli G, Wild SH, Wright AF, Campbell H, Ellinghaus D, Imboden M, Nitsch D, Brandstätter A, Kollerits B, Kedenko L, Mägi R, Stumvoll M, Kovacs P, Boban M, Campbell S, Endlich K, Völzke H, Kroemer HK, Nauck M, Völker U, Polasek O, Vitart V, Badola S, Parker AN, Ridker PM, Kardia SL, Liu Y, Curhan GC, Franke A, Rochat T, Paulweber B, Prokopenko I, Wang W, Shuldiner AR, Coresh J, Schmidt R, Ferrucci L, Shlipak MG, Borecki I, Krämer BK, Rudan I, Gyllensten U, Wilson JF, Pramstaller PP, Rettig R, Hastie N, Chasman DI, Kao WH, Heid IM, Fox CS, Vasan R, Felix SB, Watzinger N, Larson MG, Homuth G, Aragam J, Dörr M, Zweiker R, Lind L, Rodeheffer RJ, Greiser KH, Deckers JW, Stritzke J, Lackner KJ, Ingelsson E, Kullo I, Haerting J, Stricker BH, Reffelmann T, Redfield MM, Werdan K, Mitchell GF, Arnett D, Blettner M, Friedrich N, Benjamin EJ, Chambers JC, Zhang W, Lord GM, van der Harst P, Lawlor DA, Sehmi JS, Gale DP, Wass MN, Ahmadi KR, Bakker SJ, Beckmann J, Bilo HJ, Bochud M, Brown MJ, Caulfield MJ, Connell JM, Cook HT, Cotlarciuc I, Davey Smith G, de Silva R, Deng G, Devuyst O, Dikkeschei LD, Dimkovic T, Dockrell M, Dominiczak A, Ebrahim S, Eggermann T, Farrall M, Floege J, Forouhi NG, Gansevoort RT, Han X, Hedblad B, Homan van der Heide JJ, Hepkema BG, Hernandez-Fuentes M, Hypponen E, Johnson T, de Jong PE, Kleefstra N, Lagou V, Lapsley M, Li Y, Loos RJ, Luan J, Luttropp K, Maréchal C, Munroe PB, Nordfors L, Penninx BW, Perucha E, Pouta A, Roderick PJ, Ruokonen A, Sanna S, Schalling M, Schlessinger D, Schlieper G, Seelen MA, Sjögren M, Smit JH, Snieder H, Soranzo N, Spector TD, Stenvinkel P, Sternberg MJ, Swaminathan R, Ubink-Veltmaat LJ, Uda M, Vollenweider P, Wallace C, Waterworth D, Zerres K, Waeber G, Wareham NJ, Maxwell PH, McCarthy MI, Jarvelin MR, Abecasis GR, Lightstone L, Scott J, Navis G, Elliot P, Kooner JS.

Publikováno v: Nature, Vol. 11 (2011) P. 103
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Nature, 2011, 478 (7367), pp.103-109. ⟨10.1038/nature10405⟩
Ehret, G B, Munroe, P B, Rice, K M, Bochud, M, Johnson, A D, Chasman, D I, Smith, A V, Tobin, M D, Verwoert, G C, Hwang, S-J, Pihur, V, Vollenweider, P, O'Reilly, P F, Amin, N, Bragg-Gresham, J L, Teumer, A, Glazer, N L, Launer, L, Zhao, J H, Aulchenko, Y, Heath, S, Sõber, S, Parsa, A, Luan, J, Arora, P, Dehghan, A, Zhang, F, Lucas, G, Hicks, A A, Jackson, A U, Peden, J F, Tanaka, T, Wild, S H, Rudan, I, Igl, W, Milaneschi, Y, Parker, A N, Fava, C, Chambers, J C, Fox, E R, Kumari, M, Go, M J, van der Harst, P, Kao, W H L, Sjögren, M, Vitart, V, Campbell, H, Hayward, C & Wright, A F & Wilson, J F 2011, ' Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk ', Nature, vol. 478, no. 7367, pp. 103-109 . https://doi.org/10.1038/nature10405

Blood pressure is a heritable trait influenced by several biological pathways and responsive to environmental stimuli. Over one billion people worldwide have hypertension (≥140 mm Hg systolic blood pressure or ≥90 mm Hg diastolic blood pressure).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc0ab267e1ba56e2795eb10b55d87539
https://doi.org/10.1038/nature10405

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies

Autor: Reilly MP, Li M, He J, Ferguson JF, Stylianou IM, Mehta NN, Burnett MS, Devaney JM, Knouff CW, Thompson JR, Horne BD, Stewart AF, Assimes TL, Wild PS, Allayee H, Nitschke PL, Patel RS, Myocardial Infarction Genetics Consortium, Wellcome Trust Case Control Consortium, Martinelli N, Girelli D, Quyyumi AA, Anderson JL, Erdmann J, Hall AS, Schunkert H, Quertermous T, Blankenberg S, Hazen SL, Roberts R, Kathiresan S, Samani NJ, Epstein SE, Rader DJ, Qasim AN, DerOhannessian SL, Qu L, Cappola TP, Chen Z, Matthai W, Hakonarson HH, Wilensky R, Kent KM, Lindsay JM, Pichard AD, Satler L, Waksman R, Knoupf CW, Walker MC, Waterworth DM, Mosser V, Braund PS, Wright B, Balmforth AJ, Ball SG, Chen L, Wells GA, McPherson R, Lackner K, Munzel TF, Schillert A, Schnabel R, Zeller T, Ziegler A, Absher D, Hlatky MA, Iribaren C, Knowles JW, Linsel Nitschke P, König IR, Hengstenberg C, Nahrstaedt J, Peters A, Schreiber S, Wichmann E, Willenborg C, Su S, Bouzyk M, Vaccarino V, Zafari AM, Carlquist JF, Muhlestein JB, Olivieri O, Barnard J, Hartiala J, Tang WH, Burton PR, Clayton DG, Cardon LR, Craddock N, Deloukas P, Duncanson A, Kwiatkowski DP, McCarthy MI, Ouwehand WH, Todd JA, Donnelly P, Barrett JC, Davison D, Easton D, Evans DM, Leung HT, Marchini JL, Morris AP, Spencer CC, Tobin MD, Attwood AP, Boorman JP, Cant B, Everson U, Hussey JM, Jolley JD, Knight AS, Koch K, Meech E, Nutland S, Prowse CV, Stevens HE, Taylor NC, Walters GR, Walker NM, Watkins NA, Winzer T, Jones RW, McArdle WL, Ring SM, Strachan DP, Pembrey M, Breen G, St Clair D, Caesar S, Gordon Smith K, Jones L, Fraser C, Green EK, Grozeva D, Hamshere ML, Holmans PA, Jones IR, Kirov G, Moskvina V, Nikolov I, O'Donovan MC, Owen MJ, Collier DA, Elkin A, Farmer A, Williamson R, McGuffin P, Young AH, Ferrier IN, Barrett JH, Bishop DT, Iles MM, Maqbool A, Yuldasheva N, Dixon RJ, Mangino M, Stevens S, Bredin F, Tremelling M, Parkes M, Drummond H, Lees CW, Nimmo ER, Satsangi J, Fisher SA, Forbes A, Lewis CM, Onnie CM, Prescott NJ, Sanderson J, Mathew CG, Barbour J, Mohiuddin MK, Todhunter CE, Mansfield JC, Ahmad T, Cummings FR, Jewell DP, Webster J, Brown MJ, Lathrop M, Connell J, Dominiczak A, Marcano CA, Burke B, Dobson R, Gungadoo J, Lee KL, Munroe PB, Newhouse SJ, Onipinla A, Wallace C, Xue M, Caulfield M, Farrall M, Barton A, Bruce IN, Donovan H, Eyre S, Gilbert PD, Hider SL, Hinks AM, John SL, Potter C, Silman AJ, Symmons DP, Thomson W, Worthington J, Dunger DB, Widmer B, Frayling TM, Freathy RM, Lango H, Perry JR, Shields BM, Weedon MN, Hattersley AT, Hitman GA, Walker M, Elliott KS, Groves CJ, Lindgren CM, Rayner NW, Timpson NJ, Zeggini E, Newport M, Sirugo G, Lyons E, Vannberg F, Hill AV, Bradbury LA, Farrar C, Pointon JJ, Wordsworth P, Brown MA, Franklyn JA, Heward JM, Simmonds MJ, Gough SC, Seal S, Stratton MR, Rahman N, Ban M, Goris A, Sawcer SJ, Compston A, Conway D, Jallow M, Rockett KA, Bumpstead SJ, Chaney A, Downes K, Ghori MJ, Gwilliam R, Hunt SE, Inouye M, Keniry A, King E, McGinnis R, Potter S, Ravindrarajah R, Whittaker P, Widden C, Withers D, Cardin NJ, Ferreira T, Pereira Gale J, Hallgrimsdóttir IB, Bowie BN, Su Z, Teo YY, Vukcevic D, Bentley D, Meigs JB, Williams G, Nathan DM, MacRae CA, O'Donnell CJ, Ardissino D, Merlini PA, Berzuini C, Bernardinelli L, Peyvandi F, Tubaro M, Celli P, Ferrario M, Fetiveau R, Marziliano N, Galli M, Ribichini F, Rossi M, Bernardi F, Zonzin P, Piazza A, Mannucci PM, Schwartz SM, Siscovick DS, Yee J, Friedlander Y, Elosua R, Marrugat J, Lucas G, Subirana I, Sala J, Ramos R, Salomaa V, Havulinna AS, Peltonen L, Melander O, Berglund G, Voight BF, Hirschhorn JN, Asselta R, Duga S, Spreafico M, Musunuru K, Daly MJ, Purcell S, Surti A, Guiducci C, Gianniny L, Mirel D, Parkin M, Burtt N, Gabriel SB, CASARI , GIORGIO NEVIO

BACKGROUND: We tested whether genetic factors distinctly contribute to either development of coronary atherosclerosis or, specifically, to myocardial infarction in existing coronary atherosclerosis. METHODS: We did two genome-wide association studies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51ce2b0c437bbc1bd43bd9fc77d063fa
http://hdl.handle.net/11562/1028982

Common Variants at 10 Genomic Loci Influence Hemoglobin A(1C) Levels via Glycemic and Nonglycemic Pathways

Autor: Soranzo, N, Sanna, S, Wheeler, E, Gieger, C, Radke, D, Dupuis, J, Bouatia-Naji, N, Langenberg, C, Prokopenko, I, Stolerman, E, Sandhu, MS, Heeney, MM, Devaney, JM, Reilly, MP, Ricketts, SL, Stewart, AF, Voight, BF, Willenborg, C, Wright, B, Altshuler, D, Arking, D, Balkau, B, Barnes, D, Boerwinkle, E, Böhm, B, Bonnefond, A, Bonnycastle, LL, Boomsma, DI, Bornstein, SR, Böttcher, Y, Bumpstead, S, Burnett-Miller, MS, Campbell, H, Cao, A, Chambers, J, Clark, R, Collins, FS, Coresh, J, de Geus, EJ, Dei, M, Deloukas, P, Döring, A, Egan, JM, Elosua, R, Ferrucci, L, Forouhi, N, Fox, CS, Franklin, C, Franzosi, MG, Gallina, S, Goel, A, Graessler, J, Grallert, H, Greinacher, A, Hadley, D, Hall, A, Hamsten, A, Hayward, C, Heath, S, Herder, C, Homuth, G, Hottenga, JJ, Hunter-Merrill, R, Illig, T, Jackson, AU, Jula, A, Kleber, M, Knouff, CW, Kong, A, Kooner, J, Köttgen, A, Kovacs, P, Krohn, K, Kühnel, B, Kuusisto, J, Laakso, M, Lathrop, M, Lecoeur, C, Li, M, Loos, RJ, Luan, J, Lyssenko, V, Mägi, R, Magnusson, PK, Mälarstig, A, Mangino, M, Martínez-Larrad, MT, März, W, McArdle, WL, McPherson, R, Meisinger, C, Meitinger, T, Melander, O, Mohlke, KL, Mooser, VE, Morken, MA, Narisu, N, Nathan, DM, Nauck, M, O'Donnell, C, Oexle, K, Olla, N, Pankow, JS, Payne, F, Peden, JF, Pedersen, NL, Peltonen, L, Perola, M, Polasek, O, Porcu, E, Rader, DJ, Rathmann, W, Ripatti, S, Rocheleau, G, Roden, M, Rudan, I, Salomaa, V, Saxena, R, Schlessinger, D, Schunkert, H, Schwarz, P, Seedorf, U, Selvin, E, Serrano-Ríos, M, Shrader, P, Silveira, A, Siscovick, D, Song, K, Spector, TD, Stefansson, K, Steinthorsdottir, V, Strachan, DP, Strawbridge, R, Stumvoll, M, Surakka, I, Swift, AJ, Tanaka, T, Teumer, A, Thorleifsson, G, Thorsteinsdottir, U, Tönjes, A, Usala, G, Vitart, V, Völzke, H, Wallaschofski, H, Waterworth, DM, Watkins, H, Wichmann, HE, Wild, SH, Willemsen, G, Williams, GH, Wilson, JF, Winkelmann, J, Wright, AF, WTCCC, Zabena, C, Zhao, JH, Epstein, SE, Erdmann, J, Hakonarson, HH, Kathiresan, S, Khaw, KT, Roberts, R, Samani, NJ, Fleming, MD, Sladek, R, Abecasis, G, Boehnke, M, Froguel, P, Groop, L, McCarthy, MI, Kao, WH, Florez, JC, Uda, M, Wareham, NJ, Barroso, I, Meigs, JB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::d6eab3f0deff8334a67cb7c237efaf7c
https://openaccess.sgul.ac.uk/id/eprint/390/1/zdb3229.pdf

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Autor: Peter Kovacs, Alan F. Wright, Stephen Turner, Michèle M. Sale, Siim Sõber, Janoš Terzić, Elin Org, Richard S. Cooper, Alena Stančáková, Jerome I. Rotter, W. H. Linda Kao, Albert Hofman, Andrew B. Singleton, Florian Kronenberg, Jianjun Liu, Nicole L. Glazer, Christopher W. Knouff, Jennifer L. Bragg-Gresham, Juha Karjalainen, Li Ching Chang, Benjamin J. Wright, Jacqueline C.M. Witteman, Martin G. Larson, Klaus Stark, Richard J. Rodeheffer, Sharon L.R. Kardia, Douglas M. Ruderfer, Sheila Ulivi, Madhumathi Rao, Andrew A. Hicks, Eva Brand, Viviane Nicaud, Stephen G. Ball, Anna Köttgen, Germaine C. Verwoert, Anders Hamsten, Nick Shrine, Uwe Völker, Stefan Kloiber, Stephen Hancock, Emelia J. Benjamin, Bok Ghee Han, Kenneth Rice, Mark Woodward, Veronique Vitart, Karl Andersen, Nicholas J. Wareham, Robert Roberts, Maja Barbalić, David Couper, Yukinori Okada, André G. Uitterlinden, Sekar Kathiresan, Leo-Pekka Lyytikäinen, Pankaj Arora, Tatijana Zemunik, David S. Siscovick, Simonetta Guarrera, Dawn M. Waterworth, Tatjana Stojakovic, Braxton D. Mitchell, Devin Absher, Carmen A. Peralta, Mika Kivimäki, Xueling Sim, Norihiro Kato, Philippe Froguel, Keith L. Keene, Donna K. Arnett, Naoyuki Kamatani, Tazeen H. Jafar, Idris Guessous, Gunnar Jacobs, Michael M. Hoffmann, Kari Stefansson, Christian Hengstenberg, Tomonori Okamura, Inga Prokopenko, Christina Willenborg, Peter S. Braund, Rainer Rettig, Francesco U.S. Mattace-Raso, Vikal Tripathy, F. Gerald R. Fowkes, Laura R. Loehr, Harry Campbell, Margherita Cavalieri, Olle Melander, Hao Mei, I. Mateo Leach, Nicholette D. Palmer, Eva Albrecht, Naoharu Iwai, Stefan Martin Brand, Toshiko Tanaka, Jackie A. Cooper, Omri Gottesman, Manuela Uda, Angelo Scuteri, Aroon D. Hingorani, Cristiano Fava, Yusuke Nakamura, Jiang He, Min Jin Go, Serge Hercberg, Wendy L. McArdle, Philipp S. Wild, Florian Ernst, Paul Mitchell, Wolfgang Koenig, Caroline S. Fox, S. J.Cathy Fann, Janine F. Felix, Anna F. Dominiczak, Mike A. Nalls, Erik Ingelsson, Mario A. Morken, Susana Eyheramendy, Christopher Newton-Cheh, Igor Rudan, D. G. Vinay, Christopher P. Nelson, Ervin R. Fox, Xiuqing Guo, Jing Hua Zhao, Rick Twee-Hee Ong, Margaret M. Redfield, Oscar H. Franco, Yongmei Liu, Fulvio Ricceri, Mark A. Hlatky, Bernhard Paulweber, Mingyao Li, Themistocles L. Assimes, Karl Winkler, Inês Barroso, Sylvia E. Rosas, M Walker, Richard W Morris, Bo Hedblad, Hakon Hakonarson, Sonny Dandona, Peter H. Whincup, Martin Adam, Vilmundur Gudnason, Daniel Ackermann, Qiong Yang, Cuno S. P. M. Uiterwaal, Paul M. Ridker, George Davey Smith, Li Chen, C. Sinning, Terri L. Young, Jer-Yuarn Wu, Walter Palmas, Will Longstreth, Joe Devaney, Pavel Hamet, Xiaofeng Zhu, Fredrik Nyberg, Wilfried Renner, Anuj Goel, L. Adrienne Cupples, Nish Chaturvedi, Iftikhar J. Kullo, Nicholas D. Hastie, Aude Saint-Pierre, Panos Deloukas, Smita R. Kulkarni, Eric Boerwinkle, Wolfram Goessling, Gian Andri Thun, Eric J.G. Sijbrands, Shih-Jen Hwang, Carole Proust, Hirotsugu Ueshima, Kristian Hveem, Pierre Meneton, Joshua C. Denny, Olivier Devuyst, Kerri L. Wiggins, Ming-Huei Chen, Robert W. Lawrence, Robert L. Wilensky, Andre Franke, Nicole Soranzo, Simon Heath, Margot Haun, Karlhans Endlich, David Altshuler, Harald Grallert, Laurence Tiret, Luigi Ferrucci, Caroline Hayward, Sudha Seshadri, Bénédicte Stengel, Lynne E. Wagenknecht, John Attia, Andreas Ziegler, Renate B. Schnabel, Stefan Schreiber, Santosh Dahgam, Kurt Lohman, Christian M. Shaffer, Barbara Ludwig, Katalin Susztak, Chien-Hsiun Chen, Michele K. Evans, Paolo Vineis, Guo Li, Thomas J. Wang, Meena Kumari, Heather M. Stringham, Bruce M. Psaty, Norman Klopp, Halit Ongen, Ben A. Oostra, Stefan Coassin, Petra Bruse, Wei-Min Chen, Unnur Thorsteinsdottir, Charles N. Rotimi, Robert J. Carroll, Muredach P. Reilly, Niek Verweij, Dena G. Hernandez, Amy J. Swift, Barbara Kollerits, Hyung Lae Kim, Cristian Pattaro, Ivana Kolcic, Ronit Katz, John M. C. Connell, Dan E. Arking, Albert W. Dreisbach, Peter Vollenweider, C. S. Janipalli, Jian'an Luan, Erkki Vartiainen, James T. Willerson, John R. Thompson, Daniela Toniolo, Lyle J. Palmer, Alexander Teumer, Serkalem Demissie-Banjaw, Stella Trompet, James E. Hixson, Sue Shaw-Hawkins, Rossella Sorice, Bernhard R. Winkelmann, John Danesh, Anthony J. Balmforth, Toshio Ogihara, Jyotika K. Fernandes, Ulf Gyllensten, Ville Aalto, Åsa Johansson, Andres Metspalu, John F. Peden, Diana Kuh, Medea Imboden, Antonio Lupo, Su Chi Lim, Young-Jin Kim, Giovanni Malerba, Yurii S. Aulchenko, Satoshi Umemura, Ioanna Tzoulaki, Alan B. Weder, Helena Schmidt, Gerjan Navis, Susan R. Heckbert, Hans J. Rupprecht, Edward G. Lakatta, Christian Gieger, Najaf Amin, Paul Muntner, Lenore J. Launer, Ivana Persico, Hugh Watkins, Ian Ford, K. Radha Mani, Sylvia Stracke, Johanna Kuusisto, John Chalmers, Muhammad Islam, Lars Lind, Stefan R. Bornstein, Marjo-Riitta Järvelin, J. H. Young, Reiner Biffar, Santhi K. Ganesh, Kazuhiko Yamamoto, Annette Peters, Linda S. Adair, Tõnu Esko, Rebecca Hardy, Olga Jarinova, Antonietta Robino, Ruth McPherson, Benjamin F. Voight, Anne U. Jackson, Gang Shi, Stefania Bandinelli, Peter J. van der Most, John S. Gottdiener, Ying A. Wang, Mariza de Andrade, Joshua C. Bis, Leslie J. Raffel, Man Li, Jemma C. Hopewell, Bernhard O. Böhm, Aaron R. Folsom, Noël P. Burtt, S. Sidney, Diana Zelenika, Yuri Milaneschi, Pilar Galan, Iris M. Heid, Bernhard K. Krämer, Jean-Michel Gaspoz, Lynda M. Rose, Massimiliano Cocca, Jaap W. Deckers, Martin Farrall, Kent D. Taylor, Albert V. Smith, Candace Guiducci, Alan R. Shuldiner, Shiro Maeda, Liming Qu, Marilyn C. Cornelis, Xiaoling Wang, Daniel Shriner, Jutta Palmen, Yingchang Lu, Heyo K. Kroemer, Pio D'Adamo, Stephan J. L. Bakker, Tamara B. Harris, Myriam Rheinberger, Tetsuro Miki, Audrey Y. Chu, Ramachandran S. Vasan, Fuu Jen Tsai, Jan A. Staessen, Daniel I. Chasman, Jan Stritzke, Jasmin Divers, Meredith C. Foster, Jeanette M. Stafford, Maksim Struchalin, Arne Schillert, Jacques S. Beckmann, Mark E. Cooper, Jean-Charles Lambert, Mario Pirastu, Katja Butterbach, Carl G. P. Platou, Yan V. Sun, Marcus Fischer, Maciej Tomaszewski, Karl Werdan, Peng Chen, Daniel J. Rader, Thomas Münzel, Lowell F. Satler, Tom R. Gaunt, Brenda W.J.H. Penninx, William H. Matthai, John Whitfield, Rita P.S. Middelberg, Margus Viigimaa, Toshihiro Tanaka, Ida Yii Der Chen, Morris J. Brown, Valur Emilsson, J. Viikari, Wolfgang Lieb, Stephen E. Epstein, Harald Dobnig, Aravinda Chakravarti, Patrick Linsel-Nitschke, Stefan Pilz, Angela Doering, Sarah H. Wild, Patricia B. Munroe, Megan E. Rudock, Nicole Probst-Hensch, Danish Saleheen, Diederick E. Grobbee, Anke Tönjes, Narisu Narisu, Annika Rosengren, Masato Isono, Catherine Helmer, M. J.Kranthi Kumar, Alanna C. Morrison, Kay-Tee Khaw, Tanja Zeller, Jeffrey R. O'Connell, Christian Müller, Georg Homuth, Giriraj R. Chandak, Pankaj Sharma, Marcus Dörr, Veikko Salomaa, Paul F. O'Reilly, David Hadley, Hermann Brenner, Paolo Gasparini, Nanette R. Lee, Bamidele O. Tayo, Robert Clarke, Henri Wallaschofski, Marketa Sjögren, Abbas Dehghan, Melanie Waldenberger, Neil Risch, Vasyl Pihur, Jessica D. Faul, François Cambien, Christian Fuchsberger, Nicholas G. Martin, John C. Chambers, Zouhair Aherrahrou, Karl J. Lackner, Leif Groop, Matthias Olden, Wiek H. van Gilst, Mathias Gorski, Yvonne T. van der Schouw, Patrick Diemert, Christoph Bickel, Yik Ying Teo, Giorgio Pistis, Ruth J. F. Loos, Gudrun Veldre, Thorsten Reffelmann, Lude Franke, Karen L. Mohlke, Stefan Blankenberg, Massimo Mangino, Ian N. M. Day, Atsushi Takahashi, Alan B. Zonderman, Hua Tang, Reijo Laaksonen, Holly Kramer, Gary C. Curhan, Adrienne Tin, Talin Haritunians, Loic Yengo, Philip Howard, Arnika Kathleen Wagner, Anna Maria Corsi, Yen Pei C. Chang, Karin Halina Greiser, Jeanette Erdmann, Solveig Gretarsdottir, Sanjay Kinra, Alex Parker, Belen Ponte, Marina Ciullo, Michael Preuss, Tin Aung, Nicholas L. Smith, Michiaki Kubo, Richard N. Bergman, Alan S. Go, Patricia P. Chang, Gudmundur Thorgeirsson, Christa Meisinger, Gonçalo R. Abecasis, Maria Blettner, Jaana Laitinen, Daniel Taliun, Carlos Iribarren, Paavo Zitting, Thomas Lumley, Andreas Meinitzer, Wayne D. Rosamond, Daehee Kang, Johanne Tremblay, Stephan B. Felix, Colin A. McKenzie, Yuan-Tsong Chen, Lyudmyla Kedenko, Mladen Boban, Fadi J. Charchar, Adebowale Adeyemo, Brendan M. Buckley, Jennifer A. Smith, Reinhold Schmidt, Jaspal S. Kooner, Gavin Lucas, Paul Elliott, Dorairajan Prabhakaran, Tune H. Pers, Tunde Salako, Terrence Forrester, Paul Burton, Jeffrey R. Gulcher, Kelly A. Volcik, Richard M. Myers, Andreas Tomaschitz, H.-Erich Wichmann, Jie Yao, Giuseppe Matullo, Carsten A. Böger, Henry Völzke, Daniela Ruggiero, Federico Murgia, Yoshikuni Kita, Augustine Kong, Giovanni Gambaro, Cinzia Sala, Peter P. Pramstaller, James Scott, Maris Laan, Laura J. Scott, Alistair S. Hall, Sanaz Sedaghat, James F. Wilson, Joanne M. Murabito, Yi-An Ko, Honghuang Lin, Mark Seielstad, Leena Peltonen, Sven Bergmann, Thomas Meitinger, Matthias Nauck, María Soler Artigas, Thomas Illig, Nanette I. Steinle, Samer S. Najjar, Christina Loley, Debbie A Lawlor, Steven C. Hunt, Yali Li, Weihua Zhang, Jie Jin Wang, Daniele Cusi, Marco Orrù, Stephen P. Fortmann, Melissa Garcia, Barry I. Freedman, Joseph M. Lindsay, Juan P. Casas, Tomohiro Katsuya, Grant W. Montgomery, Hubert Scharnagl, Khanh-Dung H. Nguyen, Steven M. Schwartz, Afshin Parsa, Elizabeth G. Holliday, Murielle Bochud, Kiran Musunuru, Bruno H. Stricker, Lori L. Bonnycastle, Ilja M. Nolte, Timothy M. Frayling, Stefan Enroth, Michiel L. Bots, Mark J. Caulfield, Laura Portas, Vincent Chouraki, Carl D. Langefeld, Eran Halperin, Shufeng Chen, Philippa J. Talmud, Terho Lehtimäki, Steve E. Humphries, Gudmar Thorleifsson, Anika Grosshennig, Norbert Watzinger, Fumihiko Takeuchi, Pim van der Harst, Takayoshi Ohkubo, Nabila Bouatia-Naji, Erwin P. Bottinger, Roberto Elosua, Andrew Wong, Vladan Mijatovic, Maija K. Garnaas, Robert Zweiker, Joel N. Hirschhorn, Winfried März, Nilesh J. Samani, Inke R. König, Frank B. Hu, Marcus E. Kleber, Francis S. Collins, Elena Rochtchina, Ewa Zukowska-Szczechowska, Yong Li, Ayse Demirkan, Gina Hilton, G. Ehret, Thomas H. Mosley, Markus Perola, Alexandre F.R. Stewart, Josef Coresh, Olli T. Raitakari, Feng Zhang, Mark Lathrop, Michael Marmot, Yanbin Dong, Christopher J. O'Donnell, Kristin D. Marciante, Asif Rasheed, Mary F. Feitosa, Mary Susan Burnett, Rory Collins, J. Wouter Jukema, Nele Friedrich, Aida Karina Dieffenbach, Ying Wu, Yoon Shin Cho, Aaron Isaacs, Haidong Zhu, Marie Metzger, Myriam Alexander, Tanja B. Grammer, Tatiana Kuznetsova, Dabeeru C. Rao, Jayashri Aragam, Augusto D. Pichard, Jaakko Tuomilehto, Louise V. Wain, Elizabeth J. Atkinson, Tim D. Spector, Reedik Mägi, Tiit Nikopensius, Kenneth M. Kent, Guangju Zhai, Andrew D. Johnson, Menno Pruijm, David P. Strachan, Martin D. Tobin, Joban Sehmi, Janja Nahrstedt, E. Shyong Tai, Thor Aspelund, Jürgen Grässler, Hilma Holm, Matthew Denniff, Joshua W. Knowles, Tien Yin Wong, Erika Salvi, James F. Meschia, Dongfeng Gu, Ron Waksman, Stacey Gabriel, Judith A. Hoffman Bolton, Michael Boehnke, Johannes Haerting, Darina Czamara, Heribert Schunkert, Thomas Quertermous, Peter M. Nilsson, Jong-Young Lee, Yasuharu Tabara, Chittaranjan S. Yajnik, Daniel Levy, John Beilby, Fernando Rivadeneira, Claire Perret, Gudny Eiriksdottir, Jingzhong Ding, George A. Wells, Harold Snieder, Ayo P. Doumatey, Dag S. Thelle, Anja Medack, N. Charlotte Onland-Moret, Michael Stumvoll, David Ellinghaus, Ingrid B. Borecki, Tatsuhiko Tsunoda, Ian H. de Boer, M. Arfan Ikram, Andrew M. Taylor, Johannes H. Smit, Gary F. Mitchell, Anna-Liisa Hartikainen, Markku Laakso, Mark McEvoy, Andrew S. Plump, Toby Johnson, Cornelia M. van Duijn, Ozren Polasek, Wilmar Igl, Vincent Mooser, Rodney J. Scott, Mika Kähönen, Peter Schwarz

Publikováno v: Nat Commun
NATURE COMMUNICATIONS
Pattaro, C, Teumer, A, Gorski, M, Chu, A Y, Li, M, Mijatovic, V, Garnaas, M, Tin, A, Sorice, R, Li, Y, Taliun, D, Olden, M, Foster, M, Yang, Q, Chen, M-H, Pers, T H, Johnson, A D, Ko, Y-A, Fuchsberger, C, Tayo, B, Nalls, M, Feitosa, M F, Isaacs, A, Dehghan, A, d'Adamo, P, Adeyemo, A, Dieffenbach, A K, Zonderman, A B, Nolte, I M, van der Most, P J, Wright, A F, Shuldiner, A R, Morrison, A C, Hofman, A, Smith, A V, Dreisbach, A W, Franke, A, Uitterlinden, A G, Metspalu, A, Tonjes, A, Hayward, C, Campbell, H, Rudan, I, Wilson, J F, Martin, N G, Hastie, N, Polasek, O, Mitchell, P & Wild, S H & Vitart, V 2016, ' Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function ', Nature Communications, vol. 7, 10023 . https://doi.org/10.1038/ncomms10023
Nature Communications, 7
Nature Communications, 7. Nature Publishing Group
Nature communications 7 (2016): 10023. doi:10.1038/ncomms10023
info:cnr-pdr/source/autori:Cristian Pattaro 1, Alexander Teumer 2 3, Mathias Gorski 4 5, Audrey Y Chu 6, Man Li 7, Vladan Mijatovic 8, Maija Garnaas 9, Adrienne Tin 7, Rossella Sorice 10, Yong Li 11, Daniel Taliun 1, Matthias Olden 4 5, Meredith Foster 12, Qiong Yang 13, Ming-Huei Chen 13 14, Tune H Pers 15 16, Andrew D Johnson 17, Yi-An Ko 18, Christian Fuchsberger 1, Bamidele Tayo 19, Michael Nalls 20, Mary F Feitosa 21, Aaron Isaacs 22 23, Abbas Dehghan 24, Pio d'Adamo 25, Adebowale Adeyemo 26, Aida Karina Dieffenbach 27 28, Alan B Zonderman 29, Ilja M Nolte 30, Peter J van der Most 30, Alan F Wright 31, Alan R Shuldiner 32 33, Alanna C Morrison 34, Albert Hofman 24, Albert V Smith 35 36, Albert W Dreisbach 37, Andre Franke 38, Andre G Uitterlinden 39, Andres Metspalu 40 41, Anke Tonjes 42, Antonio Lupo 43, Antonietta Robino 25, Åsa Johansson 44, Ayse Demirkan 22, Barbara Kollerits 45, Barry I Freedman 46, Belen Ponte 47, Ben A Oostra 48, Bernhard Paulweber 49, Bernhard K Krämer 50, Braxton D Mitchell 32 33, Brendan M Buckley 51, Carmen A Peralta 52, Caroline Hayward 31, Catherine Helmer 53 54, Charles N Rotimi 26, Christian M Shaffer 55, Christian Müller 56 57, Cinzia Sala 58, Cornelia M van Duijn 22, Aude Saint-Pierre 1 59, Daniel Ackermann 47, Daniel Shriner 26, Daniela Ruggiero 10, Daniela Toniolo 58 60, Yingchang Lu 61, Daniele Cusi 62, Darina Czamara 63, David Ellinghaus 38, David S Siscovick 64, Douglas Ruderfer 65, Christian Gieger 66, Harald Grallert 67 68 69, Elena Rochtchina 70, Elizabeth J Atkinson 71, Elizabeth G Holliday 72 73, Eric Boerwinkle 34, Erika Salvi 62, Erwin P Bottinger 61, Federico Murgia 74, Fernando Rivadeneira 39, Florian Ernst 2, Florian Kronenberg 45, Frank B Hu 75, Gerjan J Navis 76, Gary C Curhan 77, George B Ehret 78, Georg Homuth 2, Stefan Coassin 45, Gian-Andri Thun 79 80, Giorgio Pistis 58, Giovanni Gambaro 81, Giovanni Malerba 8, Grant W Montgomery 82, Gudny Eiriksdottir 35, Gunnar Jacobs 83, Guo Li 64, H-Erich Wichmann 84 85 86, Harry Campbell 87, Helena Schmidt 88, Henri Wallaschofski 89 90, Henry Völzke 3 90, Hermann Brenner 27 28, Heyo K Kroemer 91, Holly Kramer 19, Honghuang Lin 92, I Mateo Leach 93, Ian Ford 94, Idris Guessous 95 96 97, Igor Rudan 87, Inga Prokopenko 98, Ingrid Borecki 21, Iris M Heid 4 66, Ivana Kolcic 99, Ivana Persico 74, J Wouter Jukema 100 101 102 103, James F Wilson 87, Janine F Felix 24, Jasmin Divers 104, Jean-Charles Lambert 105, Jeanette M Stafford 104, Jean-Michel Gaspoz 95, Jennifer A Smith 106, Jessica D Faul 107, Jie Jin Wang 108, Jingzhong Ding 109, Joel N Hirschhorn 15 16 110, John Attia 71 72, John B Whitfield 82, John Chalmers 111, Jorma Viikari 112, Josef Coresh 7 113, Joshua C Denny 114, Juha Karjalainen 115, Jyotika K Fernandes 116, Karlhans Endlich 117, Katja Butterbach 27, Keith L Keene 118, Kurt Lohman 46, Laura Portas 74, Lenore J Launer 119, Leo-Pekka Lyytikäinen 120, Loic Yengo 121 122 123, Lude Franke 115, Luigi Ferrucci 124, Lynda M Rose 6, Lyudmyla Kedenko 49, Madhumathi Rao 12, Maksim Struchalin 125 126, Marcus E Kleber 127, Margherita Cavalieri 128, Margot Haun 45, Marilyn C Cornelis 75, Marina Ciullo 10, Mario Pirastu 74, Mariza de Andrade 71, Mark A McEvoy 129, Mark Woodward 7 111 112 130, Martin Adam 79 80, Massimiliano Cocca 58, Matthias Nauck 89 90, Medea Imboden 79 80, Melanie Waldenberger 67, Menno Pruijm 131, Marie Metzger 132, Michael Stumvoll 42, Michele K Evans 133, Michele M Sale 134, Mika Kähönen 135, Mladen Boban 99, Murielle Bochud 136, Myriam Rheinberger 5, Niek Verweij 93, Nabila Bouatia-Naji 137 138, Nicholas G Martin 82 139, Nick Hastie 31, Nicole Probst-Hensch 79 80, Nicole Soranzo 140, Olivier Devuyst 141, Olli Raitakari 142, Omri Gottesman 61, Oscar H Franco 24, Ozren Polasek 99, Paolo Gasparini 25, Patricia B Munroe 143 144, Paul M Ridker 145, Paul Mitchell 108, Paul Muntner 146 147, Christa Meisinger 68, Johannes H Smit 148, ICBP Consortium; AGEN Consortium; CARDIOGRAM; CHARGe-Heart Failure Group; ECHOGen Consortium; Peter Kovacs 149, Philipp S Wild 150, Philippe Froguel 121 122 123, Rainer Rettig 151, Reedik Mägi 40, Reiner Biffar 152, Reinhold Schmidt 128, Rita P S Middelberg 82, Robert J Carroll 114, Brenda W Penninx 148, Rodney J Scott 153, Ronit Katz 154, Sanaz Sedaghat 24, Sarah H Wild 87, Sharon L R Kardia 106, Sheila Ulivi 155, Shih-Jen Hwang 17, Stefan Enroth 44, Stefan Kloiber 63, Stella Trompet 100, Benedicte Stengel 132, Stephen J Hancock 72 73, Stephen T Turner 156, Sylvia E Rosas 18, Sylvia Stracke 105 157, Tamara B Harris 119, Tanja Zeller 56 57, Tatijana Zemunik 99, Terho Lehtimäki 120, Thomas Illig 68, Thor Aspelund 35 36, Tiit Nikopensius 40 41, Tonu Esko 15 40 41, Toshiko Tanaka 124, Ulf Gyllensten 44, Uwe Völker 2 90, Valur Emilsson 35 158, Veronique Vitart 31, Ville Aalto 159, Vilmundur Gudnason 35 36, Vincent Chouraki 105, Wei-Min Chen 134, Wilmar Igl 44, Winfried März 160, Wolfgang Koenig 161, Wolfgang Lieb 83, Ruth J F Loos 61 162, Yongmei Liu 46, Harold Snieder 30, Peter P Pramstaller 1 163 164, Afshin Parsa 165, Jeffrey R O'Connell 32, Katalin Susztak 18, Pavel Hamet 166, Johanne Tremblay 166, Ian H de Boer 154, Carsten A Böger 5, Wolfram Goessling 9, Daniel I Chasman 6 145, Anna Köttgen 7 11, W H Linda Kao 7 113, Caroline S Fox 17 167. Collaborators: Goncalo R Abecasis, Linda S Adair, Myriam Alexander, David Altshuler, Najaf Amin, Dan E Arking, Pankaj Arora, Yurii Aulchenko, Stephan J L Bakker, Stefania Bandinelli, Ines Barroso, Jacques S Beckmann, John P Beilby, Richard N Bergman, Sven Bergmann, Joshua C Bis, Michael Boehnke, Lori L Bonnycastle, Stefan R Bornstein, Michiel L Bots, Jennifer L Bragg-Gresham, Stefan-Martin Brand, Eva Brand, Peter S Braund, Morris J Brown, Paul R Burton, Juan P Casas, Mark J Caulfield, Aravinda Chakravarti, John C Chambers, Giriraj R Chandak, Yen-Pei C Chang, Fadi J Charchar, Nish Chaturvedi, Yoon Shin Cho, Robert Clarke, Francis S Collins, Rory Collins, John M Connell, Jackie A Cooper, Matthew N Cooper, Richard S Cooper, Anna Maria Corsi, Marcus Dörr, Santosh Dahgam, John Danesh, George Davey Smith, Ian N M Day, Panos Deloukas, Matthew Denniff, Anna F Dominiczak, Yanbin Dong, Ayo Doumatey, Paul Elliott, Roberto Elosua, Jeanette Erdmann, Susana Eyheramendy, Martin Farrall, Cristiano Fava, Terrence Forrester, F Gerald R Fowkes, Ervin R Fox, Timothy M Frayling, Pilar Galan, Santhi K Ganesh, Melissa Garcia, Tom R Gaunt, Nicole L Glazer, Min Jin Go, Anuj Goel, Jürgen Grässler, Diederick E Grobbee, Leif Groop, Simonetta Guarrera, Xiuqing Guo, David Hadley, Anders Hamsten, Bok-Ghee Han, Rebecca Hardy, Anna-Liisa Hartikainen, Simon Heath, Susan R Heckbert, Bo Hedblad, Serge Hercberg, Dena Hernandez, Andrew A Hicks, Gina Hilton, Aroon D Hingorani, Judith A Hoffman Bolton, Jemma C Hopewell, Philip Howard, Steve E Humphries, Steven C Hunt, Kristian Hveem, M Arfan Ikram, Muhammad Islam, Naoharu Iwai, Marjo-Riitta Jarvelin, Anne U Jackson, Tazeen H Jafar, Charles S Janipalli, Toby Johnson, Sekar Kathiresan, Kay-Tee Khaw, Hyung-Lae Kim, Sanjay Kinra, Yoshikuni Kita, Mika Kivimaki, Jaspal S Kooner, M J Kranthi Kumar, Diana Kuh, Smita R Kulkarni, Meena Kumari, Johanna Kuusisto, Tatiana Kuznetsova, Markku Laakso, Maris Laan, Jaana Laitinen, Edward G Lakatta, Carl D Langefeld, Martin G Larson, Mark Lathrop, Debbie A Lawlor, Robert W Lawrence, Jong-Young Lee, Nanette R Lee, Daniel Levy, Yali Li, Will T Longstreth, Jian'an Luan, Gavin Lucas, Barbara Ludwig, Massimo Mangino, K Radha Mani, Michael G Marmot, Francesco U S Mattace-Raso, Giuseppe Matullo, Wendy L McArdle, Colin A McKenzie, Thomas Meitinger, Olle Melander, Pierre Meneton, James F Meschia, Tetsuro Miki, Yuri Milaneschi, Karen L Mohlke, Vincent Mooser, Mario A Morken, Richard W Morris, Thomas H Mosley, Samer Najjar, Narisu Narisu, Christopher Newton-Cheh, Khanh-Dung Hoang Nguyen, Peter Nilsson, Fredrik Nyberg, Christopher J O'Donnell, Toshio Ogihara, Takayoshi Ohkubo, Tomonori Okamura, Rick Twee-Hee Ong, Halit Ongen, N Charlotte Onland-Moret, Paul F O'Reilly, Elin Org, Marco Orru, Walter Palmas, Jutta Palmen, Lyle J Palmer, Nicholette D Palmer, Alex N Parker, John F Peden, Leena Peltonen, Markus Perola, Vasyl Pihur, Carl G P Platou, Andrew Plump, Dorairajan Prabhakaran, Bruce M Psaty, Leslie J Raffel, Dabeeru C Rao, Asif Rasheed, Fulvio Ricceri, Kenneth M Rice, Annika Rosengren, Jerome I Rotter, Megan E Rudock, Siim Sõber, Tunde Salako, Danish Saleheen, Veikko Salomaa, Nilesh J Samani, Steven M Schwartz, Peter E H Schwarz, Laura J Scott, James Scott, Angelo Scuteri, Joban S Sehmi, Mark Seielstad, Sudha Seshadri, Pankaj Sharma, Sue Shaw-Hawkins, Gang Shi, Nick R G Shrine, Eric J G Sijbrands, Xueling Sim, Andrew Singleton, Marketa Sjögren, Nicholas L Smith, Maria Soler Artigas, Tim D Spector, Jan A Staessen, Alena Stancakova, Nanette I Steinle, David P Strachan, Heather M Stringham, Yan V Sun, Amy J Swift, Yasuharu Tabara, E-Shyong Tai, Philippa J Talmud, Andrew Taylor, Janos Terzic, Dag S Thelle, Martin D Tobin, Maciej Tomaszewski, Vikal Tripathy, Jaakko Tuomilehto, Ioanna Tzoulaki, Manuela Uda, Hirotsugu Ueshima, Cuno S P M Uiterwaal, Satoshi Umemura, Pim van der Harst, Yvonne T van der Schouw, Wiek H van Gilst, Erkki Vartiainen, Ramachandran S Vasan, Gudrun Veldre, Germaine C Verwoert, Margus Viigimaa, D G Vinay, Paolo Vineis, Benjamin F Voight, Peter Vollenweider, Lynne E Wagenknecht, Louise V Wain, Xiaoling Wang, Thomas J Wang, Nicholas J Wareham, Hugh Watkins, Alan B Weder, Peter H Whincup, Kerri L Wiggins, Jacqueline C M Witteman, Andrew Wong, Ying Wu, Chittaranjan S Yajnik, Jie Yao, J H Young, Diana Zelenika, Guangju Zhai, Weihua Zhang, Feng Zhang, Jing Hua Zhao, Haidong Zhu, Xiaofeng Zhu, Paavo Zitting, Ewa Zukowska-Szczechowska, Yukinori Okada, Jer-Yuarn Wu, Dongfeng Gu, Fumihiko Takeuchi, Atsushi Takahashi, Shiro Maeda, Tatsuhiko Tsunoda, Peng Chen, Su-Chi Lim, Tien-Yin Wong, Jianjun Liu, Terri L Young, Tin Aung, Yik-Ying Teo, Young Jin Kim, Daehee Kang, Chien-Hsiun Chen, Fuu-Jen Tsai, Li-Ching Chang, S-J Cathy Fann, Hao Mei, James E Hixson, Shufeng Chen, Tomohiro Katsuya, Masato Isono, Eva Albrecht, Kazuhiko Yamamoto, Michiaki Kubo, Yusuke Nakamura, Naoyuki Kamatani, Norihiro Kato, Jiang He, Yuan-Tsong Chen, Toshihiro Tanaka, Muredach P Reilly, Heribert Schunkert, Themistocles L Assimes, Alistair Hall, Christian Hengstenberg, Inke R König, Reijo Laaksonen, Ruth McPherson, John R Thompson, Unnur Thorsteinsdottir, Andreas Ziegler, Devin Absher, Li Chen, L Adrienne Cupples, Eran Halperin, Mingyao Li, Kiran Musunuru, Michael Preuss, Arne Schillert, Gudmar Thorleifsson, George A Wells, Hilma Holm, Robert Roberts, Alexandre F R Stewart, Stephen Fortmann, Alan Go, Mark Hlatky, Carlos Iribarren, Joshua Knowles, Richard Myers, Thomas Quertermous, Steven Sidney, Neil Risch, Hua Tang, Stefan Blankenberg, Renate Schnabel, Christoph Sinning, Karl J Lackner, Laurence Tiret, Viviane Nicaud, Francois Cambien, Christoph Bickel, Hans J Rupprecht, Claire Perret, Carole Proust, Thomas F Münzel, Maja Barbalic, Ida Yii-Der Chen, Serkalem Demissie-Banjaw, Aaron Folsom, Thomas Lumley, Kristin Marciante, Kent D Taylor, Kelly Volcik, Solveig Gretarsdottir, Jeffrey R Gulcher, Augustine Kong, Kari Stefansson, Gudmundur Thorgeirsson, Karl Andersen, Marcus Fischer, Anika Grosshennig, Patrick Linsel-Nitschke, Klaus Stark, Stefan Schreiber, Zouhair Aherrahrou, Petra Bruse, Angela Doering, Norman Klopp, Patrick Diemert, Christina Loley, Anja Medack, Janja Nahrstedt, Annette Peters, Arnika K Wagner, Christina Willenborg, Bernhard O Böhm, Harald Dobnig, Tanja B Grammer, Michael M Hoffmann, Andreas Meinitzer, Bernhard R Winkelmann, Stefan Pilz, Wilfried Renner, Hubert Scharnagl, Tatjana Stojakovic, Andreas Tomaschitz, Karl Winkler, Candace Guiducci, Noel Burtt, Stacey B Gabriel, Sonny Dandona, Olga Jarinova, Liming Qu, Robert Wilensky, William Matthai, Hakon H Hakonarson, Joe Devaney, Mary Susan Burnett, Augusto D Pichard, Kenneth M Kent, Lowell Satler, Joseph M Lindsay, Ron Waksman, Christopher W Knouff, Dawn M Waterworth, Max C Walker, Stephen E Epstein, Daniel J Rader, Christopher P Nelson, Benjamin J Wright, Anthony J Balmforth, Stephen G Ball, Laura R Loehr, Wayne D Rosamond, Emelia Benjamin, Talin Haritunians, David Couper, Joanne Murabito, Ying A Wang, Bruno H Stricker, Patricia P Chang, James T Willerson, Stephan B Felix, Norbert Watzinger, Jayashri Aragam, Robert Zweiker, Lars Lind, Richard J Rodeheffer, Karin Halina Greiser, Jaap W Deckers, Jan Stritzke, Erik Ingelsson, Iftikhar Kullo, Johannes Haerting, Thorsten Reffelmann, Margaret M Redfield, Karl Werdan, Gary F Mitchell, Donna K Arnett, John S Gottdiener, Maria Blettner, Nele Friedrich/titolo:Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function./doi:10.1038%2Fncomms10023/rivista:Nature communications/anno:2016/pagina_da:10023/pagina_a:/intervallo_pagine:10023/volume:7
Nature Communications
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Nature Communications [E], 7. Nature Publishing Group
Nature Communications, Vol. 7 (2016) P. 10023
Nature Communications, 7:10023. Nature Publishing Group
Nature Communications, 7(10023). Nature Publishing Group
Pattaro, Cristian; Teumer, Alexander; Gorski, Mathias; Chu, Audrey Y; Li, Man; Mijatovic, Vladan; Garnaas, Maija; Tin, Adrienne; Sorice, Rossella; Li, Yong; Taliun, Daniel; Olden, Matthias; Foster, Meredith; Yang, Qiong; Chen, Ming-Huei; Pers, Tune H; Johnson, Andrew D; Ko, Yi-An; Fuchsberger, Christian; Tayo, Bamidele; ... (2016). Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nature communications, 7, p. 10023. Nature Publishing Group 10.1038/ncomms10023
Nature Communications, Vol 7, Iss 1, Pp 1-19 (2016)
Nature Communications, vol. 7, pp. 10023

Reduced glomerular filtration rate defines chronic kidney disease and is associated with cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide association studies for estimated glomerular filtration rate (eGFR), combinin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::392dcabbb8f3da3321c1b9ee79fbcba8
https://doi.org/10.1038/ncomms10023

RANTES/CCL5 and risk for coronary events: results from the MONICA/KORA Augsburg case-cohort, Athero-Express and CARDIoGRAM studies

Autor: Herder, C., Peeters, W., Illig, T., Baumert, J., Kleijn, D. P., Moll, F. L., Poschen, U., Klopp, N., Müller-Nurasyid, M., Roden, M., Preuss, M., CARDIoGRAM Consortium, Karakas, M., Christa Meisinger, Thorand, B., Pasterkamp, G., Koenig, W., Assimes, T. L., Deloukas, P., Erdmann, J., Holm, H., Kathiresan, S., König, I. R., Mcpherson, R., Reilly, M. P., Roberts, R., Samani, N. J., Schunkert, H., Stewart, A. F.

Publikováno v: PloS one, vol 6, iss 12
Scopus-Elsevier
PLoS ONE, Vol 6, Iss 12, p e25734 (2011)
PLoS ONE
PLoS ONE 6:e25734 (2011)
Plos One, vol. 6, no. 12, pp. e25734

BACKGROUND: The chemokine RANTES (regulated on activation, normal T-cell expressed and secreted)/CCL5 is involved in the pathogenesis of cardiovascular disease in mice, whereas less is known in humans. We hypothesised that its relevance for atheroscl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c95ee6e71d3a3c20a3a7ab79be7a7ad
https://escholarship.org/uc/item/50r7s80q