Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Hakim Hocini"'
Critical contribution of mitochondria in the development of cardiomyopathy linked to desmin mutation
Autor:
Yeranuhi Hovhannisyan, Zhenlin Li, Domitille Callon, Rodolphe Suspène, Vivien Batoumeni, Alexis Canette, Jocelyne Blanc, Hakim Hocini, Cécile Lefebvre, Nora El-Jahrani, Maria Kitsara, Aurore L’honoré, Ekaterini Kordeli, Paul Fornes, Jean-Paul Concordet, Gérard Tachdjian, Anne-Marie Rodriguez, Jean-Pierre Vartanian, Anthony Béhin, Karim Wahbi, Pierre Joanne, Onnik Agbulut
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Background Beyond the observed alterations in cellular structure and mitochondria, the mechanisms linking rare genetic mutations to the development of heart failure in patients affected by desmin mutations remain unclear due in part, to the
Externí odkaz:
https://doaj.org/article/0f03334029de42209d19c57d3d283372
Autor:
Fabiola Blengio, Hakim Hocini, Laura Richert, Cécile Lefebvre, Mélany Durand, Boris Hejblum, Pascaline Tisserand, Chelsea McLean, Kerstin Luhn, Rodolphe Thiebaut, Yves Levy
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113101- (2023)
Summary: Ebola virus disease is a severe hemorrhagic fever with a high fatality rate. We investigate transcriptome profiles at 3 h, 1 day, and 7 days after vaccination with Ad26.ZEBOV and MVA-BN-Filo. 3 h after Ad26.ZEBOV injection, we observe an inc
Externí odkaz:
https://doaj.org/article/5b22ee762b5744dbb4e4be1ccb253909
Autor:
Emilie Boissady, Yara Abi Zeid Daou, Estelle Faucher, Matthias Kohlhauer, Fanny Lidouren, Cynthia El Hedjaj, Sophie Chateau‐Joubert, Hakim Hocini, Sophie Hue, Bijan Ghaleh, Renaud Tissier
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 3 (2023)
Background High‐mobility group box 1 (HMGB1) is a major promotor of ischemic injuries and aseptic inflammatory responses. We tested its inhibition on neurological outcome and systemic immune response after cardiac arrest (CA) in rabbits. Methods an
Externí odkaz:
https://doaj.org/article/d5d67af310f04df087e7bb1445eccb45
Autor:
Yves Lévy, Aurélie Wiedemann, Boris P. Hejblum, Mélany Durand, Cécile Lefebvre, Mathieu Surénaud, Christine Lacabaratz, Matthieu Perreau, Emile Foucat, Marie Déchenaud, Pascaline Tisserand, Fabiola Blengio, Benjamin Hivert, Marine Gauthier, Minerva Cervantes-Gonzalez, Delphine Bachelet, Cédric Laouénan, Lila Bouadma, Jean-François Timsit, Yazdan Yazdanpanah, Giuseppe Pantaleo, Hakim Hocini, Rodolphe Thiébaut
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105715- (2023)
Externí odkaz:
https://doaj.org/article/32e1ea9f7f5d46c1957c649d8f43315b
Autor:
Mariangela Cavarelli, Stéphane Hua, Naima Hantour, Sabine Tricot, Nicolas Tchitchek, Céline Gommet, Hakim Hocini, Catherine Chapon, Nathalie Dereuddre-Bosquet, Roger Le Grand
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Mariangela Cavarelli et al. utilize cynomolgus macaque colorectal tissue explants to explore the effect of leukocytospermic seminal plasma (LSP) on SIVmac251 infection. Their results suggest that mucosal SIV infection is influenced by the inflammator
Externí odkaz:
https://doaj.org/article/e148333ddf904b1ea51de80c040200ca
Autor:
Aurélie Wiedemann, Emile Foucat, Hakim Hocini, Cécile Lefebvre, Boris P. Hejblum, Mélany Durand, Miriam Krüger, Alpha Kabinet Keita, Ahidjo Ayouba, Stéphane Mély, José-Carlos Fernandez, Abdoulaye Touré, Slim Fourati, Claire Lévy-Marchal, Hervé Raoul, Eric Delaporte, Lamine Koivogui, Rodolphe Thiébaut, Christine Lacabaratz, Yves Lévy, PostEboGui Study Group
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Patients who have recovered from Ebola virus can have ongoing health problems. Here, the authors show that 35 Guinean survivors of the last West African Ebola epidemic have a chronic disease with high inflammatory cytokine expression and other marker
Externí odkaz:
https://doaj.org/article/525bc83b567f4212a1ba8e49aa100061
Autor:
Yves Lévy, Aurélie Wiedemann, Boris P. Hejblum, Mélany Durand, Cécile Lefebvre, Mathieu Surénaud, Christine Lacabaratz, Matthieu Perreau, Emile Foucat, Marie Déchenaud, Pascaline Tisserand, Fabiola Blengio, Benjamin Hivert, Marine Gauthier, Minerva Cervantes-Gonzalez, Delphine Bachelet, Cédric Laouénan, Lila Bouadma, Jean-François Timsit, Yazdan Yazdanpanah, Giuseppe Pantaleo, Hakim Hocini, Rodolphe Thiébaut
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102711- (2021)
Summary: The identification of patients with coronavirus disease 2019 and high risk of severe disease is a challenge in routine care. We performed cell phenotypic, serum, and RNA sequencing gene expression analyses in severe hospitalized patients (n
Externí odkaz:
https://doaj.org/article/61e089ec34614597aa6b9bb37427c685
Autor:
Jérôme Kervevan, Aurélie Bouteau, Juliane S Lanza, Adele Hammoudi, Sandra Zurawski, Mathieu Surenaud, Lydie Dieudonné, Marion Bonnet, Cécile Lefebvre, Hakim Hocini, Romain Marlin, Aurélie Guguin, Barbara Hersant, Oana Hermeziu, Elisabeth Menu, Christine Lacabaratz, Jean-Daniel Lelièvre, Gerard Zurawski, Véronique Godot, Sandrine Henri, Botond Z Igyártó, Yves Levy, Sylvain Cardinaud
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009749 (2021)
The main avenue for the development of an HIV-1 vaccine remains the induction of protective antibodies. A rationale approach is to target antigen to specific receptors on dendritic cells (DC) via fused monoclonal antibodies (mAb). In mouse and non-hu
Externí odkaz:
https://doaj.org/article/d8ccad982f5d4146b6cb7179328b5e87
Vaccine Inoculation Route Modulates Early Immunity and Consequently Antigen-Specific Immune Response
Autor:
Pierre Rosenbaum, Nicolas Tchitchek, Candie Joly, André Rodriguez Pozo, Lev Stimmer, Sébastien Langlois, Hakim Hocini, Leslie Gosse, David Pejoski, Antonio Cosma, Anne-Sophie Beignon, Nathalie Dereuddre-Bosquet, Yves Levy, Roger Le Grand, Frédéric Martinon
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Vaccination is one of the most efficient public healthcare measures to fight infectious diseases. Nevertheless, the immune mechanisms induced in vivo by vaccination are still unclear. The route of administration, an important vaccination parameter, c
Externí odkaz:
https://doaj.org/article/3a103ecb80fc4060981474719f13c5bd
Autor:
Emilie Boissady, Matthias Kohlhauer, Fanny Lidouren, Hakim Hocini, Cécile Lefebvre, Sophie Chateau‐Jouber, Nicolas Mongardon, Nicolas Deye, Alain Cariou, Philippe Micheau, Bijan Ghaleh, Renaud Tissier
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 23 (2020)
Background Total liquid ventilation (TLV) has been shown to prevent neurological damage though ultrafast cooling in animal models of cardiac arrest. We investigated whether its neuroprotective effect could be explained by mitigation of early inflamma
Externí odkaz:
https://doaj.org/article/a8256e4436864b33ad902914c7347c05