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pro vyhledávání: '"Hakdo Kim"'
Autor:
Hayoung Hwang, Hyukjoon Choi, Kyung-Hee Kim, Woo-Sik Kim, Hakdo Kim, Jayhyuk Myung, Geumwoo Lee, Kyungjin Jung, Wonken Choung, Jungwook Chin, Jeongmin Joo, Min Park, Seong Heon Kim, Su Min Jang, Jae Soo Lim, Tae-ho Jang, Eunmi Hong, Boram Lee, Deokmo Yang
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:2275-2282
As a potential treatment of type 2 diabetes, a novel PPARγ non-TZD full agonist, compound 18 (BR102375) was identified from the original lead BR101549 by the SAR efforts of the labile metabolite control through bioisosteres approach. In vitro assess