Synthesis, in silico ADME, molecular docking and in vitro cytotoxicity evaluation of stilbene linked 1,2,3-triazoles

Autor: Arnika Das, Sujeet Kumar, Leentje Persoons, Dirk Daelemans, Dominique Schols, Hakan Alici, Hakan Tahtaci, Subhas S. Karki

Publikováno v: Heliyon, Vol 7, Iss 1, Pp e05893- (2021)

Series of (E)-1-benzyl-4-((4-styrylphenoxy)methyl)-1H-1,2,3-triazoles 7a-x were obtained by Wittig reaction between 4-((1-benzyl-1H-1,2,3-triazol-4-yl)methoxy)benzaldehydes 5a-d and benzyl triphenylphosphonium halides 6a-f in benzene. The structures

Externí odkaz: https://doaj.org/article/5d3c28f2e0a5444abd5c18141ab3470d

Frontotemporal Dementia-Related V57E Mutation Impairs Mitochondrial Function and Alters the Structural Properties of CHCHD10

Autor: Hakan Alici, Vladimir N. Uversky, Tian Liu, David E. Kang, Junga Alexa Woo, Orkid Coskuner-Weber

Publikováno v: ACS Chemical Neuroscience.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0a2991fdda59523fa9141cd073bf641c
https://doi.org/10.1021/acschemneuro.3c00125

Structures of the Wild-Type and S59L Mutant CHCHD10 Proteins Important in Amyotrophic Lateral Sclerosis–Frontotemporal Dementia

Autor: Hakan Alici, Vladimir N. Uversky, David E. Kang, Junga Alexa Woo, Orkid Coskuner-Weber

Publikováno v: ACS Chemical Neuroscience. 13:1273-1280

The S59L genetic mutation of the mitochondrial coiled-coil-helix-coiled-coil-helix domain-containing protein 10 (CHCHD10) is involved in the pathogenesis of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The wild-type and muta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdefd45f3f50513d604761ae1225acad
https://doi.org/10.1021/acschemneuro.2c00011

Novel Thioether-Bridged 2,6-Disubstituted and 2,5,6-Trisubstituted Imidazothiadiazole Analogues: Synthesis, Antiproliferative Activity, ADME, and Molecular Docking Studies

Autor: Ibrahim Ozcan, Senem Akkoc, Hakan Alici, Seval Capanlar, Onur Sahin, Hakan Tahtaci

Publikováno v: Chemistrybiodiversity.

© 2022 Wiley-VHCA AG, Zurich, Switzerland.In this study, starting from 2-amino-1,3,4-thiadiazole derivatives (3–5), a new series of 2,6-disubstituted (compounds 7–15) and 2,5,6-trisubstituted (compounds 16–33) imidazo[2,1-b][1,3,4]-thiadiazole

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c471d54a6e587fddbde7e172f3d660a
https://pubmed.ncbi.nlm.nih.gov/36445849

Contributors

Autor: Murali Aarthy, Bidisha Acharya, Priyanka Aggarwal, Nabeel Ahmad, Natarajan Aiswarya, Hakan Alici, Khattab Al-Khafaji, Anshul Assaiya, Saurabh Bansal, Suparna Bhar, Aparna Bhardwaj, Dhiraj Bhatia, Neel Sarovar Bhavesh, Joanna Bons, Krishnananda Chattopadhyay, Purna Bahadur Chetri, Orkid Coskuner-Weber, Soumya De, Veronica Isabel Dodero, Jack A. Elias, Agusti Emperador, Roberto Giambruno, Marco Giampà, Rajanish Giri, Steffen P. Graether, Akshita Gupta, Smita Gupta, Md Anzarul Haque, Orkun Hasekioglu, Md Imtaiyaz Hassan, Prajna N. Hebbar, A. Hema Naveena, Maria Georgina Herrera, Alexander-Maurice Illig, Asimul Islam, Matej Janežič, Jeyaraman Jeyakanthan, Suchitra Kamle, Kota Kasahara, Punit Kaur, Heena Khan, Janesh Kumar, Prateek Kumar, Ritesh Kumar, Saravanan Kumar, Vijay Kumar, Pooja Kumari, Varsha Kumari, Bishwajit Kundu, Chun Geun Lee, Dawei Li, Xubo Lin, Snigdha Maiti, Narattam Mandal, Anil Mhashal, Parul Mishra, Ajitha Mohan, Sandip Mukherjee, Sunandan Mukherjee, Niharika Nag, Koomity V. Nageswar, Fouzia Nasim, Santoshi Nayak, Siddharth Neog, Chandran Nithin, Amy O’Broin, Olujide O. Olubiyi, Laura Orellana, Aditya K. Padhi, Amrita Arpita Padhy, Dipak N. Patil, Vijay Kumar Prajapati, Insaf Ahmed Qureshi, Chandrashekar Narayanan Rahul, Anjali Rajwar, Kristijan Ramadan, S. Rashmi, Tadi Sai Ratnakar, Arun Kumar Rawat, Jacob Rose, Anwesha Roy, Jakob Rupert, Subhashree Sahoo, Nikita V. Saibo, Suman Samantray, Nikhil H. Samarth, Madhumathi Sanjeevi, Achinta Sannigrahi, Santanu Sasidharan, Prakash Saudagar, Birgit Schilling, Kanagaraj Sekar, Mansi Sharma, Pradeep Sharma, Sujata Sharma, Vinita Sharma, Kummari Shivani, Abhay Narayan Singh, Anamika Singh, Appu K. Singh, Meenakshi Singh, Sanjeev Kumar Singh, Satyendra Singh, Shailza Singh, Shalini Singh, Sudhir Kumar Singh, Tej P. Singh, Tugba Taskin-Tok, Arianne L. Theiss, Nicolo Tonali, Timir Tripathi, Vishal Trivedi, Vladimir N. Uversky, Payal Vaswani, K. Venuprasad, Elsa Zacco, Kam Y.J. Zhang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ebc2116dc18e4be848d6c848acde5d9
https://doi.org/10.1016/b978-0-323-90264-9.09988-8