Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Hak-Zoo Kim"'
Autor:
Ismaïl Hendaoui, Elise Lavergne, Heun-Sik Lee, Seong Hyun Hong, Hak-Zoo Kim, Christelle Parent, Nathalie Heuzé-Vourc'h, Bruno Clément, Orlando Musso
Publikováno v:
PLoS ONE, Vol 7, Iss 3 (2012)
Externí odkaz:
https://doaj.org/article/1565769d45c34d9e98d888626da79978
Autor:
Ismaïl Hendaoui, Elise Lavergne, Heun-Sik Lee, Seong Hyun Hong, Hak-Zoo Kim, Christelle Parent, Nathalie Heuzé-Vourc'h, Bruno Clément, Orlando Musso
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30601 (2012)
The Wnt/β-catenin pathway controls cell proliferation, death and differentiation. Several families of extracellular proteins can antagonize Wnt/β-catenin signaling, including the decoy receptors known as secreted frizzled related proteins (SFRPs),
Externí odkaz:
https://doaj.org/article/0eab4dd16f904b48abb0ffd56bd94a62
Autor:
Keehoon Jung, Jung-Eun Lee, Hak-Zoo Kim, Ho Min Kim, Beom Seok Park, Seong-Ik Hwang, Jie-Oh Lee, Sun Chang Kim, Gou Young Koh
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7403 (2009)
Lipopolysaccharide (LPS), the Gram-negative bacterial outer membrane glycolipid, induces sepsis through its interaction with myeloid differentiation protein-2 (MD-2) and Toll-like receptor 4 (TLR4). To block interaction between LPS/MD-2 complex and T
Externí odkaz:
https://doaj.org/article/3ecc6ccb36eb48d9b76b5905c6e30110
Autor:
Hail Kim, Shinae Kang, Gou Young Koh, Chul Woo Ahn, Yoshikazu Nakaoka, Ho Seon Park, Jong Suk Park, Junyeop Lee, Seung Pyo Lee, Hak Zoo Kim
Publikováno v:
Diabetes. 68:774-786
Islets are highly vascularized for prompt insulin secretion. Although angiopoietin-1 (Ang1) is a well-known angiogenic factor, its role in glucose homeostasis remains largely unknown. The objective of this study was to investigate whether and how Ang
Autor:
Shinae Kang, Arim Choi, Sung Jin Moon, Eui-Cheol Shin, Young Woo Park, Ji Yoon Ha, Chul Woo Ahn, Min Young Lee, Ho Seon Park, Jong Suk Park, Min Yeong Choi, Hak Zoo Kim
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 1394, p 1394 (2020)
Journal of Clinical Medicine
Volume 9
Issue 5
Journal of Clinical Medicine
Volume 9
Issue 5
Cluster of differentiation 93 (CD93) is a glycoprotein expressed in activated endothelial cells. The extracellular portion of CD93 can be secreted as a soluble form (sCD93) under inflammatory conditions. As diabetic nephropathy (DN) is a well-known i
Autor:
Nam Kyu Lim, Jeung Eun Lee, Hoon Ki Sung, Gou Young Koh, Byeong Hwa Jeon, Kyung Eun Kim, Ho Min Kim, Minah Kim, Young Jun Koh, Seong Ik Hwang, Do-Hyun Nam, Keehoon Jung, Ook Joon Yoo, Choon Ju Jeon, Nuri Oh, Hak Zoo Kim, Andras Nagy, Gyun Min Lee
Publikováno v:
Cancer Cell. 18(2):171-184
SummaryTwo vascular growth factor families, VEGF and the angiopoietins, play critical and coordinate roles in tumor progression and metastasis. A single inhibitor targeting both VEGF and angiopoietins is not available. Here, we developed a chimeric d
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1793:772-780
Despite that angiopoietin-2 (Ang2) produces more versatile and dynamic functions than angiopoietin-1 (Ang1) in angiogenesis and inflammation, the molecular mechanism that underlies this difference is still unknown. To define the role of oligomerizati
Publikováno v:
The Protein Journal. 27:319-326
A designed angiopoietin-1 (Ang1) chimeric protein with nonleaky angiogenic activity, COMP-Ang1, is an effective alternative to native Ang1 for therapeutic angiogenesis in vivo. Recombinant Chinese hamster ovary (rCHO) cell lines expressing a high lev
Autor:
Kazuomi Noda, Tatsuhiko Kodama, Hak Zoo Kim, Gou Young Koh, Keisuke Sako, Takashi Minami, Shigetomo Fukuhara, Naoki Mochizuki, Masabumi Shibuya, Nobuyuki Takakura
Publikováno v:
Nature Cell Biology. 10:513-526
Tie2 belongs to the receptor tyrosine kinase family and functions as a receptor for Angiopoietin-1 (Ang1). Gene-targeting analyses of either Ang1 or Tie2 in mice reveal a critical role of Ang1-Tie2 signalling in developmental vascular formation. It r
Autor:
Koung Li Kim, Duk-Kyung Kim, Hak-Zoo Kim, Wonhee Suh, Jung-Sun Lee, Eun-Seok Jeon, Sun-Hwa Song, Yeon-Lim Suh, In-Soon Shin, Gou Young Koh, Jeong-Min Kim, Jonghoe Byun
Publikováno v:
Cardiovascular Research
Aims The endothelium has emerged recently as a therapeutic target in the treatment of hypertension because endothelial dysfunction and subsequent vascular rarefaction cause target organ damage and further elevate blood pressure (BP). It led us to hyp