Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Hak Zoo Kim"'
Autor:
Hail Kim, Shinae Kang, Gou Young Koh, Chul Woo Ahn, Yoshikazu Nakaoka, Ho Seon Park, Jong Suk Park, Junyeop Lee, Seung Pyo Lee, Hak Zoo Kim
Publikováno v:
Diabetes. 68:774-786
Islets are highly vascularized for prompt insulin secretion. Although angiopoietin-1 (Ang1) is a well-known angiogenic factor, its role in glucose homeostasis remains largely unknown. The objective of this study was to investigate whether and how Ang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2153fb1eb9c3751b44b2932b232d9d8c
https://doi.org/10.2337/db18-0864
https://doi.org/10.2337/db18-0864
Autor:
Shinae Kang, Arim Choi, Sung Jin Moon, Eui-Cheol Shin, Young Woo Park, Ji Yoon Ha, Chul Woo Ahn, Min Young Lee, Ho Seon Park, Jong Suk Park, Min Yeong Choi, Hak Zoo Kim
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 1394, p 1394 (2020)
Journal of Clinical Medicine
Volume 9
Issue 5
Journal of Clinical Medicine
Volume 9
Issue 5
Cluster of differentiation 93 (CD93) is a glycoprotein expressed in activated endothelial cells. The extracellular portion of CD93 can be secreted as a soluble form (sCD93) under inflammatory conditions. As diabetic nephropathy (DN) is a well-known i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28bf9f8aa8e4260e69a0d9231b861dfc
https://www.mdpi.com/2077-0383/9/5/1394
https://www.mdpi.com/2077-0383/9/5/1394
Autor:
Ismaïl Hendaoui, Elise Lavergne, Heun-Sik Lee, Seong Hyun Hong, Hak-Zoo Kim, Christelle Parent, Nathalie Heuzé-Vourc'h, Bruno Clément, Orlando Musso
Publikováno v:
PLoS ONE, Vol 7, Iss 3 (2012)
Externí odkaz:
https://doaj.org/article/1565769d45c34d9e98d888626da79978
Autor:
Ismaïl Hendaoui, Elise Lavergne, Heun-Sik Lee, Seong Hyun Hong, Hak-Zoo Kim, Christelle Parent, Nathalie Heuzé-Vourc'h, Bruno Clément, Orlando Musso
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30601 (2012)
The Wnt/β-catenin pathway controls cell proliferation, death and differentiation. Several families of extracellular proteins can antagonize Wnt/β-catenin signaling, including the decoy receptors known as secreted frizzled related proteins (SFRPs),
Externí odkaz:
https://doaj.org/article/0eab4dd16f904b48abb0ffd56bd94a62
Autor:
Keehoon Jung, Jung-Eun Lee, Hak-Zoo Kim, Ho Min Kim, Beom Seok Park, Seong-Ik Hwang, Jie-Oh Lee, Sun Chang Kim, Gou Young Koh
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7403 (2009)
Lipopolysaccharide (LPS), the Gram-negative bacterial outer membrane glycolipid, induces sepsis through its interaction with myeloid differentiation protein-2 (MD-2) and Toll-like receptor 4 (TLR4). To block interaction between LPS/MD-2 complex and T
Externí odkaz:
https://doaj.org/article/3ecc6ccb36eb48d9b76b5905c6e30110
Autor:
Nam Kyu Lim, Jeung Eun Lee, Hoon Ki Sung, Gou Young Koh, Byeong Hwa Jeon, Kyung Eun Kim, Ho Min Kim, Minah Kim, Young Jun Koh, Seong Ik Hwang, Do-Hyun Nam, Keehoon Jung, Ook Joon Yoo, Choon Ju Jeon, Nuri Oh, Hak Zoo Kim, Andras Nagy, Gyun Min Lee
Publikováno v:
Cancer Cell. 18(2):171-184
SummaryTwo vascular growth factor families, VEGF and the angiopoietins, play critical and coordinate roles in tumor progression and metastasis. A single inhibitor targeting both VEGF and angiopoietins is not available. Here, we developed a chimeric d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70580e365c6789bd1d09fd8af59799bb
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1793:772-780
Despite that angiopoietin-2 (Ang2) produces more versatile and dynamic functions than angiopoietin-1 (Ang1) in angiogenesis and inflammation, the molecular mechanism that underlies this difference is still unknown. To define the role of oligomerizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24ea97b2347cababdee3a901ebe5551c
https://doi.org/10.1016/j.bbamcr.2009.01.018
https://doi.org/10.1016/j.bbamcr.2009.01.018
Publikováno v:
The Protein Journal. 27:319-326
A designed angiopoietin-1 (Ang1) chimeric protein with nonleaky angiogenic activity, COMP-Ang1, is an effective alternative to native Ang1 for therapeutic angiogenesis in vivo. Recombinant Chinese hamster ovary (rCHO) cell lines expressing a high lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd1ecb3cc4ff34652e8fcb4e656a614
https://doi.org/10.1007/s10930-008-9140-5
https://doi.org/10.1007/s10930-008-9140-5
Autor:
Kazuomi Noda, Tatsuhiko Kodama, Hak Zoo Kim, Gou Young Koh, Keisuke Sako, Takashi Minami, Shigetomo Fukuhara, Naoki Mochizuki, Masabumi Shibuya, Nobuyuki Takakura
Publikováno v:
Nature Cell Biology. 10:513-526
Tie2 belongs to the receptor tyrosine kinase family and functions as a receptor for Angiopoietin-1 (Ang1). Gene-targeting analyses of either Ang1 or Tie2 in mice reveal a critical role of Ang1-Tie2 signalling in developmental vascular formation. It r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb19f7e663602f8a877bb59c47a3d2ff
https://doi.org/10.1038/ncb1714
https://doi.org/10.1038/ncb1714
Autor:
Koung Li Kim, Duk-Kyung Kim, Hak-Zoo Kim, Wonhee Suh, Jung-Sun Lee, Eun-Seok Jeon, Sun-Hwa Song, Yeon-Lim Suh, In-Soon Shin, Gou Young Koh, Jeong-Min Kim, Jonghoe Byun
Publikováno v:
Cardiovascular Research
Aims The endothelium has emerged recently as a therapeutic target in the treatment of hypertension because endothelial dysfunction and subsequent vascular rarefaction cause target organ damage and further elevate blood pressure (BP). It led us to hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::797f8386a62111d212dc78c42a2abc4c
http://europepmc.org/articles/PMC5436684
http://europepmc.org/articles/PMC5436684