Preoperative hemoglobin thresholds for survival equity in women and men

Autor: Florian Rumpf, Lotta Hof, Oliver Old, Patrick Friederich, Jens Friedrich, Josef Thoma, Maria Wittmann, Kai Zacharowski, Suma Choorapoikayil, Patrick Meybohm, German Patient Blood Management Network Collaborators, Olaf Baumhove, Samuel de Leeuw van Weenen, Markus Velten, Claudia Neumann, Andrea Kirfel, Nadine Straßberger-Nerschbach, Heidi Ehrentraut, Daniel Grigutsch, Vera Guttenthaler, Alma Puskarevic, Ghaith Mohssen, Jan Görtzen, Diana Narita, Lighvani Barbara, Michael Josef Huber, Valeska Lea Blum, Sabine Isik, Vanessa Neef, Florian Piekarski, Thomas Walther, Harald Keller, Andreas Schnitzbauer, Thomas Schmitz-Rixen, Kyriakos Oikonomou, Bjoern Steffen, Stefan Zeuzem, Marcus Czabanka, Felix Chun, Ingo Marzi, Timo Stöver, Shahram Ghanaati, Frank Louwen, M. Markus Mueller, Christoph Geisen, Erhard Seyfried, Eva Herrmann, Alexandra Bayer, Henry Weigt, Björn Lange, Ansgar Raadts, Christoph Haas, Johannes Duemmler, Ulf Lorenzen, Matthias Pagel, Thomas Puehler, Julius Pochhammer, Tim Klueter, Hajrullah Ahmeti, Dirk Bauerschlag, Henning Wieker, René Rusch, Gerd Molter, München Klinik, Janina Dana Jenke, Kira Kieserling, Dennie Scholle, U. Andrea Steinbicker, Alexander Zarbock, Sven Martens, Andres Schrader, G. R. Geissler, H. Hillmann, Georg Lenz, Klaus Schwendner, Viola Weber, Philipp Helmer, Sebastian Hottenrott, Peter Kranke, Daniel Roeder, Tobias Schlesinger, Magdalena Sitter, Jan Stumpner

Publikováno v: Frontiers in Medicine, Vol 11 (2024)

Anemia affects humans throughout life, and is linked to higher morbidity and mortality. Unclear is whether hemoglobin values are equivalent between women and men. This study evaluates the association of preoperative hemoglobin levels with in-hospital

Externí odkaz: https://doaj.org/article/2bb7ee9256ae4c87b8c1c3d7958cf0ac

Insights into Gene Regulation under Temozolomide-Promoted Cellular Dormancy and Its Connection to Stemness in Human Glioblastoma

Autor: Carolin Kubelt, Dana Hellmold, Daniela Esser, Hajrullah Ahmeti, Michael Synowitz, Janka Held-Feindt

Publikováno v: Cells, Vol 12, Iss 11, p 1491 (2023)

The aggressive features of glioblastoma (GBM) are associated with dormancy. Our previous transcriptome analysis revealed that several genes were regulated during temozolomide (TMZ)-promoted dormancy in GBM. Focusing on genes involved in cancer progre

Externí odkaz: https://doaj.org/article/b82fccb6be13481d82b94b41a4d9f8a4

Extensive Growth of an Anaplastic Meningioma

Autor: Hajrullah Ahmeti, Homajoun Maslehaty, Athanasios K. Petridis, Alexandros Doukas, Mehran Mahvash, Harald Barth, H. M. Mehdorn

Publikováno v: Case Reports in Neurological Medicine, Vol 2013 (2013)

We present the case of a 30-year-old male patient with an almost complete destruction of the calvarial bone through an anaplastic meningioma diagnosed in line with dizziness. Neuroimaging revealed an extensive growing, contrast enhancing lesion expan

Externí odkaz: https://doaj.org/article/4aebb9d9cb77474aa055fc4ab19b632c

Measurements of Functional Network Connectivity Using Resting State Arterial Spin Labeling During Neurosurgery

Autor: Santosh Kesari, Stephan Ulmer, Michael Synowitz, Michael Helle, Jens Fiehler, Olav Jansen, Lasse Dührsen, Thomas Lindner, Hajrullah Ahmeti

Publikováno v: World Neurosurgery. 157:152-158

In neurosurgery, an exact delineation of functional areas is of great interest to spare important regions to ensure the best possible outcome for the patient, i.e. maximum removal while maintaining the highest possible quality of life. Preoperative i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d13a19cee6f9de6d14f89654fa03190
https://doi.org/10.1016/j.wneu.2021.10.107

Intratumoral Distribution of Lactate and the Monocarboxylate Transporters 1 and 4 in Human Glioblastoma Multiforme and Their Relationships to Tumor Progression-Associated Markers

Autor: Sönke Peters, Michael Synowitz, Jan-Bernd Hövener, Lukas Huber, Janka Held-Feindt, Hajrullah Ahmeti, Carolin Kubelt, Monika Huhndorf, Olav Jansen, Gesa Cohrs

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 6254, p 6254 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 17

(1) Background: Metabolic reprogramming has been postulated to be one of the hallmarks of cancer, thus representing a promising therapeutic target also in glioblastoma multiforme (GBM). Hypoxic tumor cells produce lactate, and monocarboxylate transpo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5bd75f6685a15758b899de4c873f104
https://www.mdpi.com/1422-0067/21/17/6254